This study examined various source-separating sanitation systems to evaluate their environmental performance, providing decision-makers with insights for selecting an appropriate system for a newly developed neighborhood in Sweden. A full consequential LCA was conducted to account for resource recovery and substitution. The local wastewater treatment plant WWTP was modeled as a reference. Secondly, a urine recycling system was introduced to treat 75 % of the collected urine, with the remainder piped to the WWTP. Thirdly, a black and greywater (BW&GW) treatment system handling all generated wastewater was examined. Finally, a hybrid source-separating system combining urine, black, and greywater was investigated. The results indicated that the four scenarios exhibited global warming potentials (GWP) of 78, 62, 32, and 24 kg CO2-eq per PE/ y. Recycling urine as fertilizer led to a 20 % reduction in the GWP of the reference. It also reduced other impact categories, with a 55 %, 65 %, and 45 % reduction in eutrophication, ozone depletion, and acidification, respectively. The BW&GW system achieved a 60 % reduction over the reference GWP, mainly due to fertilizer, biogas, and cleanwater recovery. Integrating urine, black, and greywater recycling in the final scenario achieved a 25 % reduction compared to the BW&GW scenario, primarily due to lowering of the ammonia stripping GWP and the additional fertilizer recovery. Based on sensitivity analyses, switching citric acid for sulfuric acid reduced the GWP of the urine stabilization unit process by 101 %, from 15.47 to -0.14 kg CO2-eq per PE/ y. Ultimately, the findings suggest that the fully decentralized source-separating sanitation system incorporating urine, blackwater, and greywater recycling, particularly when combined with 70 % energy recovery at the urine concentrator, is most favorable. ©