Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Imaging agent of a TRPA1 inhibitor
Novandi Chemistry AB, Sweden.
RISE, SP – Sveriges Tekniska Forskningsinstitut, SP Process Development, Analys och fastfas.ORCID iD: 0000-0002-8849-234x
AstraZeneca, Sweden; FOI Swedish Defence Research Agency, Sweden.
2013 (English)In: Journal of labelled compounds & radiopharmaceuticals, ISSN 0362-4803, E-ISSN 1099-1344, Vol. 56, no 9-10, p. 536-537Article in journal (Refereed) Published
Abstract [en]

A method for the preparation of [3'-3H]-4-(2'-chloro-6'- hydroxyphenyl)-2-thioxo-3,4-dihydro-1H-indeno[1,2-d]pyrimidin-5 (2H)-one (1), a TRPA1 inhibitor, was developed for the evaluation of imaging properties of a class of TRPA1 inhibitors. 1 was prepared via tritiation of a protected benzaldehyde followed by a tetrachlorosilane catalyzed multicomponent one-step fusion and was obtained at a specific activity of 0.9 TBq/mmol. A 3H-NMR spectrum on 13.5MBq at 75 μM was recorded.

Place, publisher, year, edition, pages
2013. Vol. 56, no 9-10, p. 536-537
Keywords [en]
3H, Isotopically labeled synthesis, NMR, TRPA1
National Category
Natural Sciences
Identifiers
URN: urn:nbn:se:ri:diva-6554DOI: 10.1002/jlcr.3030Scopus ID: 2-s2.0-84894342540Local ID: 23838OAI: oai:DiVA.org:ri-6554DiVA, id: diva2:964392
Available from: 2016-09-08 Created: 2016-09-08 Last updated: 2023-05-09Bibliographically approved

Open Access in DiVA

No full text in DiVA

Other links

Publisher's full textScopus

Authority records

Bernlind, Alexandra

Search in DiVA

By author/editor
Bernlind, Alexandra
By organisation
Analys och fastfas
In the same journal
Journal of labelled compounds & radiopharmaceuticals
Natural Sciences

Search outside of DiVA

GoogleGoogle Scholar

doi
urn-nbn

Altmetric score

doi
urn-nbn
Total: 136 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf