To address grand societal challenges, united actions from multiple actors are required. Innovation management in mission-oriented, collaborative contexts is however a particularly tall order. In parallel, ISO standards for innovation management have become available. This paper has studied nine collaborative innovation initiatives (diverse domains/levels) to capture their experiences and challenges. These were analysed regarding the relevance of applying standard-based frameworks for innovation management in such settings. It is concluded that a standard-based framework for innovation management can be applied as a support for both planning and execution, making a relevant starting point to ensure crucial aspects are not overlooked. Thereto, this paper also presents a tentative methodology aiming to contribute to the planning and execution of such collaborative innovation initiatives. The methodology contains (1) a preparatory step of mapping the initiative, and (2) a second step utilising a set of guiding aspects in the form of questions and claims.