Human factors engineering is a key parameter in High-Performance Marine Craft (HPMC) design since the human tolerance to working conditions aboard, in fact, decides the operational limits. So far, the deficiency of the knowledge on how the crew is influenced by the working conditions in terms of health risk and work performance has lead the designing process to exit before incorporating the human element when determining these operational limits. Knowledge, on the relationship of the physical and perceived exposure conditions and on risk factors for health and work performance impairments, would open up possibilities for drawing the operational limits at the design stage and providing feedback to the crew during operations. This is investigated in a research program and the current study pilot test a set of High-Performance Marine Craft Personnel (HPMCP) in order to collect data on their work exposure, health and performance impairments. The study collects subjective and objective data and investigates their correlation and the potential risk factors. Although the amount of data collected is too limited to draw direct conclusions, the pilot test confirms the feasibility of the set-up and the method giving good inputs and experience to the research crew.