Change search
Refine search result
1 - 19 of 19
CiteExportLink to result list
Permanent link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Rows per page
  • 5
  • 10
  • 20
  • 50
  • 100
  • 250
Sort
  • Standard (Relevance)
  • Author A-Ö
  • Author Ö-A
  • Title A-Ö
  • Title Ö-A
  • Publication type A-Ö
  • Publication type Ö-A
  • Issued (Oldest first)
  • Issued (Newest first)
  • Created (Oldest first)
  • Created (Newest first)
  • Last updated (Oldest first)
  • Last updated (Newest first)
  • Disputation date (earliest first)
  • Disputation date (latest first)
  • Standard (Relevance)
  • Author A-Ö
  • Author Ö-A
  • Title A-Ö
  • Title Ö-A
  • Publication type A-Ö
  • Publication type Ö-A
  • Issued (Oldest first)
  • Issued (Newest first)
  • Created (Oldest first)
  • Created (Newest first)
  • Last updated (Oldest first)
  • Last updated (Newest first)
  • Disputation date (earliest first)
  • Disputation date (latest first)
Select
The maximal number of hits you can export is 250. When you want to export more records please use the Create feeds function.
  • 1.
    Berg, Robert
    et al.
    RISE, SP – Sveriges Tekniska Forskningsinstitut, SP Process Development, Katalys.
    Lee, Taegyo
    Wilson, Tyler W
    Ryberg, Per
    Hartwig, John F
    Rhodium-Catalyzed Enantioselective Silylation of Arene C–H Bonds: Desymmetrization of Diarylmethanols2015In: Journal of the American Chemical Society, ISSN 0002-7863, E-ISSN 1520-5126, Vol. 137, no 21, p. 6742-6745Article in journal (Refereed)
    Abstract [en]

    We report a Rh-catalyzed, enantioselective silylation of arene C–H bonds directed by a (hydrido)silyl group. (Hydrido)silyl ethers that are formed in situ by hydrosilylation of benzophenone or its derivatives undergo asymmetric C–H silylation in high yield with excellent enantioselectivity in the presence of [Rh(cod)Cl]2 and a chiral bisphosphine ligand. The stereoselectivity of this process also allows enantioenriched diarylmethanols to react with site selectivity at one aryl group over the other. Enantioenriched benzoxasiloles from the silylation process undergo a range of transformations to form C–C, C–O, C–I, or C–Br bonds.

  • 2.
    Bernlind, Alexandra
    RISE, SP – Sveriges Tekniska Forskningsinstitut, SP Process Development, Analys och fastfas.
    Imaging agent of a TRPA1 inhibitor2013In: Journal of labelled compounds & radiopharmaceuticals, ISSN 0362-4803, E-ISSN 1099-1344, Vol. 56, no 9-10, p. 536-537Article in journal (Refereed)
  • 3.
    Boge, Lukas
    et al.
    RISE, SP – Sveriges Tekniska Forskningsinstitut, SP Kemi Material och Ytor, Life Science. Department of Chemical and Chemical Engineering, Applied Chemistry, Chalmers University of Technology.
    Bysell, Helena
    RISE, SP – Sveriges Tekniska Forskningsinstitut, SP Kemi Material och Ytor, Life Science.
    Ringstad, Lovisa
    RISE, SP – Sveriges Tekniska Forskningsinstitut, SP Kemi Material och Ytor, Life Science.
    Wennman, David
    RISE, SP – Sveriges Tekniska Forskningsinstitut, SP Process Development, Analys och fastfas.
    Umerska, A.
    Cassisa, V.
    Eriksson, J.
    Joly-Guillou, M. -L
    Edwards, K.
    Andersson, M.
    Lipid-based liquid crystals as carriers for antimicrobial peptides: Phase behavior and antimicrobial effect2016In: Langmuir, ISSN 0743-7463, E-ISSN 1520-5827, Vol. 32, no 17, p. 4217-4228Article in journal (Refereed)
    Abstract [en]

    The number of antibiotic-resistant bacteria is increasing worldwide, and the demand for novel antimicrobials is constantly growing. Antimicrobial peptides (AMPs) could be an important part of future treatment strategies of various bacterial infection diseases. However, AMPs have relatively low stability, because of proteolytic and chemical degradation. As a consequence, carrier systems protecting the AMPs are greatly needed, to achieve efficient treatments. In addition, the carrier system also must administrate the peptide in a controlled manner to match the therapeutic dose window. In this work, lyotropic liquid crystalline (LC) structures consisting of cubic glycerol monooleate/water and hexagonal glycerol monooleate/oleic acid/water have been examined as carriers for AMPs. These LC structures have the capability of solubilizing both hydrophilic and hydrophobic substances, as well as being biocompatible and biodegradable. Both bulk gels and discrete dispersed structures (i.e., cubosomes and hexosomes) have been studied. Three AMPs have been investigated with respect to phase stability of the LC structures and antimicrobial effect: AP114, DPK-060, and LL-37. Characterization of the LC structures was performed using small-angle X-ray scattering (SAXS), dynamic light scattering, ζ-potential, and cryogenic transmission electron microscopy (Cryo-TEM) and peptide loading efficacy by ultra performance liquid chromatography. The antimicrobial effect of the LCNPs was investigated in vitro using minimum inhibitory concentration (MIC) and time-kill assay. The most hydrophobic peptide (AP114) was shown to induce an increase in negative curvature of the cubic LC system. The most polar peptide (DPK-060) induced a decrease in negative curvature while LL-37 did not change the LC phase at all. The hexagonal LC phase was not affected by any of the AMPs. Moreover, cubosomes loaded with peptides AP114 and DPK-060 showed preserved antimicrobial activity, whereas particles loaded with peptide LL-37 displayed a loss in its broad-spectrum bactericidal properties. AMP-loaded hexosomes showed a reduction in antimicrobial activity.

  • 4.
    Bollmark, Martin
    et al.
    RISE, SP – Sveriges Tekniska Forskningsinstitut, SP Process Development, Substans och formulering.
    Berg, Robert
    RISE, SP – Sveriges Tekniska Forskningsinstitut, SP Process Development, Katalys.
    A scalable route to 5-substituted 3-isoxazolol fibrinolysis inhibitor AZD65642014In: Organic Process Research & Development, ISSN 1083-6160, E-ISSN 1520-586X, Vol. 18, no 8, p. 952-959Article in journal (Refereed)
  • 5.
    Guiamba, I
    et al.
    Department of Biology and Biological Engineering, Food and Nutrition Science, Chalmers University of Technology; Departamento de Engenharia Química, Faculdade de Engenharia, Universidade Eduardo Mondlane.
    Ahrné, L
    RISE, SP – Sveriges Tekniska Forskningsinstitut, SP Process Development. Department of Biology and Biological Engineering, Food and Nutrition Science, Chalmers University of Technology.
    Khan, M.A.M.
    Departamento de Engenharia Química, Faculdade de Engenharia, Universidade Eduardo Mondlane.
    Svanberg, U
    Department of Biology and Biological Engineering, Food and Nutrition Science, Chalmers University of Technology.
    Retention of β-carotene and vitamin C in dried mango osmotically pretreated with osmotic solutions containing calcium or ascorbic acid2016In: Food and Bioproducts Processing, ISSN 0960-3085, E-ISSN 1744-3571, Vol. 98, p. 320-326Article in journal (Refereed)
    Abstract [en]

    The retention of vitamin C and carotenoids was studied in the cv. 'Tommy Atkins' mango as affected by osmotic dehydration prior to hot air drying. Osmotic dehydration (OD) was carried out over 15 h at 25°C using sucrose solutions of 45°BRIX with and without 1% (w/w) calcium chloride or 1% ascorbic acid with a fruit to solution ratio of 1:10 (w/w), and the OD-treated mango samples were then dried in an air convection oven at 50°C or 70°C. An osmotic pretreatment before drying significantly reduced the drying time and prevented colour change in dried mango. Addition of calcium in the OD solution significantly improved vitamin C retention, on average from 44% to 57%. However, the addition of ascorbic acid to the osmotic solution highly increased the retention of vitamin C content in the dried mango. The retention of all-trans-β-carotene was significantly lower in all OD treated mango samples dried at 50°C but remained unchanged in OD-treated mango samples with calcium or vitamin C dried at 70°C. Moreover, osmotic dehydration with and without additives reduced the ratio of 13-cis-β-carotene to all-trans-β-carotene. The results showed that the addition of calcium or vitamin C to the osmotic solution can improve the nutritional value of dried mango. © 2016 The Institution of Chemical Engineers.

  • 6. Karlsson, S.
    et al.
    Sörensen, H.
    Andersen, S. M.
    Cruz, A.
    Ryberg, P.
    RISE, SP – Sveriges Tekniska Forskningsinstitut, SP Process Development.
    An Enantioselective Hydrogenation of an Alkenoic Acid as a Key Step in the Synthesis of AZD27162016In: Organic Process Research & Development, ISSN 1083-6160, E-ISSN 1520-586X, Vol. 20, no 2, p. 262-269Article in journal (Refereed)
    Abstract [en]

    A classical resolution of a racemic carboxylic acid through salt formation and an asymmetric hydrogenation of an α,β-unsaturated carboxylic acid were investigated in parallel to prepare an enantiomerically pure alkanoic acid used as a key intermediate in the synthesis of an antiplaque candidate drug. After an extensive screening of rhodium- and ruthenium-based catalysts, we developed a rhodium-catalyzed hydrogenation that gave the alkanoic acid with 90% ee, and after a subsequent crystallization with (R)-1-phenylethanamine, the ee was enriched to 97%. The chiral acid was then used in sequential Negishi and Suzuki couplings followed by basic hydrolysis of a nitrile to an amide to give the active pharmaceutical ingredient in 22% overall yield. © 2016 American Chemical Society.

  • 7.
    Koch, D
    et al.
    Rönninge College, Rönninge, Sweden.
    Koch, E
    Karo Bio, Huddinge, Sweden.
    Desarbre, E
    Basilea Pharmaceutica Ltd., Basel, Switzerland.
    Stensland, B
    AstraZeneca, Södertälje, Sweden.
    Svensson, P.H.
    RISE, SP – Sveriges Tekniska Forskningsinstitut, SP Process Development, Analys och fastfas. Department of Applied Physical Chemistry, Royal Institute of Technology, Stockholm, Sweden.
    Bergman, J
    Department of Biosciences at Novum, Huddinge, Sweden.
    2,2′-Biindolyl Reactions with Aldehydes2016In: European Journal of Organic Chemistry, ISSN 1434-193X, E-ISSN 1099-0690, Vol. 2016, no 7, p. 1389-1396Article in journal (Refereed)
    Abstract [en]

    2,2′-Biindolyl has been condensed with aromatic and aliphatic aldehydes and products featuring 10-membered rings have been obtained. Thus, benzaldehyde gave compound 24a as the primary product, which readily underwent transannular oxidative coupling to 25a. The structures of both compounds were confirmed by X-ray crystallography. The product from 2,2′-biindolyl and formaldehyde under strongly acidic conditions was slightly different leading to compound 11, whose structure also was confirmed by X-ray crystallography. In this case, two molecules of 2,2′-biindolyl reacted with six molecules of formaldehyde. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  • 8.
    Leven, Lotta
    et al.
    RISE, SP – Sveriges Tekniska Forskningsinstitut, JTI Institutet för Jordbruks- och Miljöteknik.
    Eveborn, David
    RISE, SP – Sveriges Tekniska Forskningsinstitut, JTI Institutet för Jordbruks- och Miljöteknik.
    Ljung, Emelie
    RISE, SP – Sveriges Tekniska Forskningsinstitut, JTI Institutet för Jordbruks- och Miljöteknik.
    Gros Calvo, M
    Dalahmeh, Sahar
    Jönsson, Håkan
    Ahrens, Lutz
    Wiberg, Karin
    Lundin, Göran
    RISE, SP – Sveriges Tekniska Forskningsinstitut, SP Process Development.
    Läkemedel i källsorterat klosettvatten och latrin2016Report (Other academic)
  • 9.
    Minidis, Anna
    RISE, SP – Sveriges Tekniska Forskningsinstitut, SP Process Development, Substans och formulering.
    A novel scalable process to the GSK3β inhibitor AZD8926 based on a heterocyclic ziegler coupling2013In: Organic Process Research & Development, ISSN 1083-6160, E-ISSN 1520-586X, Vol. 17, no 4, p. 672-678Article in journal (Refereed)
  • 10.
    Odille, Fabrice
    et al.
    RISE, SP – Sveriges Tekniska Forskningsinstitut, SP Process Development, Processutveckling och kristallisation.
    Stenemyr, Anna
    RISE, SP – Sveriges Tekniska Forskningsinstitut, SP Process Development, Processutveckling och kristallisation.
    Development of a grignard-type reaction for manufacturing in a continuous-flow reactor2014In: International journal of thermophysics, ISSN 0195-928X, E-ISSN 1572-9567, Vol. 18, no 11, p. 1545-1549Article in journal (Refereed)
  • 11.
    Schipper, Nicolaas
    et al.
    RISE, SP – Sveriges Tekniska Forskningsinstitut, SP Process Development.
    Meijer, Thomas
    RISE, SP – Sveriges Tekniska Forskningsinstitut, SP Process Development.
    Nagpal, Vibhu
    RISE, SP – Sveriges Tekniska Forskningsinstitut, SP Process Development.
    Helleday, Thomas
    Scilife Laboratory, Karolinska institutet, Solna.
    Validation and development of MTH1 inhibitors for treatment of cancer2016In: Annals of Oncology, ISSN 0923-7534, E-ISSN 1569-8041Article in journal (Refereed)
    Abstract [en]

    Previously, we showed cancer cells rely on the MTH1 protein to prevent incorporation of otherwise deadly oxidised nucleotides into DNA and we developed MTH1 inhibitors which selectively kill cancer cells. Recently, several new and potent inhibitors of MTH1 were demonstrated to be non-toxic to cancer cells, challenging the utility of MTH1 inhibition as a target for cancer treatment.

  • 12.
    Svensson, Per H
    RISE, SP – Sveriges Tekniska Forskningsinstitut, SP Process Development, Analys och fastfas.
    De novo determination of the crystal structure of a large drug molecule by crystal structure prediction-based powder NMR crystallography2013In: Journal of the American Chemical Society, ISSN 0002-7863, E-ISSN 1520-5126, Vol. 135, no 46, p. 17501-17507Article in journal (Refereed)
    Abstract [en]

    The crystal structure of form 4 of the drug 4-[4-(2-adamantylcarbamoyl)-5-tert-butyl-pyrazol-1-yl]benzoic acid is determined using a protocol for NMR powder crystallography at natural isotopic abundance combining solid-state (1)H NMR spectroscopy, crystal structure prediction, and density functional theory chemical shift calculations. This is the first example of NMR crystal structure determination for a molecular compound of previously unknown structure, and at 422 g/mol this is the largest compound to which this method has been applied so far.

  • 13.
    Svensson, Per H
    RISE, SP – Sveriges Tekniska Forskningsinstitut, SP Process Development, Analys och fastfas.
    In silico solid state perturbation for solubility improvement2015In: ChemMedChem, ISSN 1860-7179, E-ISSN 1860-7187, Vol. 9, no 4, p. 724-726Article in journal (Refereed)
  • 14.
    Svensson, Per H
    RISE, SP – Sveriges Tekniska Forskningsinstitut, SP Process Development, Analys och fastfas.
    Oxidative ring expansion of spirocyclic oxindole derivatives2014In: Journal of Organic Chemistry, ISSN 0022-3263, E-ISSN 1520-6904, Vol. 79, no 19, p. 9065-9073Article in journal (Refereed)
  • 15.
    Svensson, Per H
    et al.
    RISE, SP – Sveriges Tekniska Forskningsinstitut, SP Process Development, Analys och fastfas.
    Cong, Jiayan
    Kinschel, Dominik
    Daniel, Quentin
    Safdari, Majid
    Gabrielsson, Erik
    Chen, Hong
    Sunce, Licheng
    Kloo, Lars
    Bis(1,1-bis(2-pyridyl)ethane)copper(I/II) as an efficient redox couple for liquid dye-sensitized solar cells2016In: Journal of Materials Chemistry, ISSN 0959-9428, E-ISSN 1364-5501, Vol. 4, p. 14550-14554Article in journal (Refereed)
    Abstract [en]

    A new redox couple, [Cu(bpye)2]+/2+, has been synthesized, and applied in dye-sensitized solar cells (DSSCs). Overall efficiencies of 9.0% at 1 sun and 9.9% at 0.5 sun were obtained, which are considerably higher than those obtained for cells containing the reference redox couple, [Co(bpy)3]2+/3+. These results represent a record for copper-based complex redox systems in liquid DSSCs. Fast dye regeneration, sluggish recombination loss processes, faster electron self-exchange reactions and suitable redox potentials are the main reasons for the observed increase in efficiency. In particular, the main disadvantage of cobalt complex-based redox couples, charge-transport problems, appears to be resolved by a change to copper complex redox couples. The results make copper complex-based redox couples very promising for further development of highly efficient DSSCs.

  • 16.
    Svensson, Per H
    et al.
    RISE, SP – Sveriges Tekniska Forskningsinstitut, SP Process Development, Analys och fastfas.
    Gu, Chungang
    Lewis, Richard J
    Wells, Andrew S
    Hosagrahara, Vinayak P
    Johnsson, Eskil
    Hallström, Gösta
    Lipid Peroxide-Mediated Oxidative Rearrangement of the Pyrazinone Carboxamide Core of Neutrophil Elastase Inhibitor AZD9819 in Blood Plasma Samples.2015In: Drug Metabolism And Disposition, ISSN 0090-9556, E-ISSN 1521-009X, Vol. 43, p. 1441-1449Article in journal (Refereed)
    Abstract [en]

    This study focused on the mechanistic interpretation of ex vivo oxidation of a candidate drug in blood plasma samples. An unexpected lipid peroxide-mediated epoxidation followed by a dramatic rearrangement led to production of a five-membered oxazole derivative from the original six-membered pyrazinone-carboxamide core of a human neutrophil elastase inhibitor, 6-(1-(4-cyanophenyl)-1H-pyrazol-5-yl)-N-ethyl-5-methyl-3-oxo-4-(3-(trifluoromethyl)phenyl)-3,4-dihydropyrazine-2-carboxamide (AZD9819). The rearranged oxidation product 2-(1-(4-cyanophenyl)-1H-pyrazol-5-yl)-5-(N-ethylacetamido)-N-(3-(trifluoromethyl)phenyl)oxazole-4-carboxamide was characterized by accurate-mass tandem mass spectrometry fragmentations, by two-dimensional NMR and X-ray crystallography of an authentic standard, and by incorporation of an (18)O atom from molecular (18)O2 to the location predicted by our proposed mechanism. The lipid peroxide-mediated oxidation was demonstrated by using human low-density lipoprotein (LDL) in pH 7.4 phosphate buffer and by inhibiting the oxidation with ascorbic acid or l-glutathione, two antioxidants effective in both plasma and the LDL incubation. A nucleophilic mechanism for the epoxidation of AZD9819 by lipid hydroperoxides explains the prevention of its ex vivo oxidation by acidification of the plasma samples. The discovery of the lipid peroxide-dependent oxidation of an analyte and the means of prevention could provide valuable information for biotransformation and bioanalysis.

  • 17.
    Svensson, Per H
    et al.
    RISE, SP – Sveriges Tekniska Forskningsinstitut, SP Process Development, Analys och fastfas.
    Safdari, Majid
    Tam Hoang, Minh
    Oh, Ilwhan
    Kloo, Lars
    Gardner, James M
    Layered 2D alkyldiammonium lead iodide perovskites: synthesis, characterization, and use in solar cells2016In: Journal of Materials Chemistry, ISSN 0959-9428, E-ISSN 1364-5501, Vol. 8, no 4, p. 1627-1640Article in journal (Refereed)
    Abstract [en]

    The synthetic route and properties of three 2D hybrid organic/inorganic lead iodide perovskite materials are reported. The 2D perovskites were synthesized from the reaction between PbI2and the di-cations of 1,4-diaminobutane, 1,6-diaminohexane, and 1,8-diaminooctane. The resulting products were [NH3(CH2)4NH3]PbI4 (BdAPbI4), [NH3(CH2)6NH3]PbI4 (HdAPbI4), and [NH3(CH2)8NH3]PbI4 (OdAPbI4). Structural characterization shows that two dimensional perovskite structures were formed with inorganic structural planes separated by organic layers. Absorption spectra show band gaps of 2.37 eV (BdAPbI4), 2.44 eV (HdAPbI4), and 2.55 eV (OdAPbI4). The 2D perovskite materials were investigated as light absorbing materials in solid state solar cells. The best performing material under moist, ambient conditions was BdAPbI4(1.08% efficiency), which was comparable to methylammonium Pb(II) iodide (MAPbI3) solar cells (2.1% efficiency) manufactured and studied under analogous conditions. When compared to MAPbI3, the 2D materials have larger band gaps and lower photoconductivity, while BdAPbI4based solar cells shows a comparable absorbed photon-to-current efficiency as compared toMAPbI3 based ones.

  • 18.
    Svensson, Per H
    et al.
    RISE, SP – Sveriges Tekniska Forskningsinstitut, SP Process Development, Analys och fastfas.
    Wennman, David
    RISE, SP – Sveriges Tekniska Forskningsinstitut, SP Process Development, Analys och fastfas.
    Roddis, Ylva
    RISE, SP – Sveriges Tekniska Forskningsinstitut, SP Process Development, Analys och fastfas.
    Lundin, Göran
    RISE, SP – Sveriges Tekniska Forskningsinstitut, SP Process Development, Analys och fastfas.
    Bernlind, Alexandra
    RISE, SP – Sveriges Tekniska Forskningsinstitut, SP Process Development, Analys och fastfas.
    Hammarström, Lars G J
    Harmel, Robert K
    Granath, Mikael
    Ringom, Rune
    Gravenfors, Ylva
    Färnegårdh, Katarina
    Kitambi, Satish
    Lehmann, Fredrik
    Ernfors, Patrik
    The Oncolytic Efficacy and in Vivo Pharmacokinetics of [2-(4-Chlorophenyl)quinolin-4-yl](piperidine-2-yl)methanol (Vacquinol-1) Are Governed by Distinct Stereochemical Features2016In: Journal of Medicinal Chemistry, ISSN 0022-2623, E-ISSN 1520-4804, Vol. 59, no 18, p. 8577-8592Article in journal (Refereed)
    Abstract [en]

    Glioblastoma remains an incurable brain cancer. Drugs developed in the past 20 years have not improved the prognosis for patients, necessitating the development of new treatments. We have previously reported the therapeutic potential of the quinoline methanol Vacquinol-1 (1) that targets glioblastoma cells and induces cell death by catastrophic vacuolization. Compound 1 is a mixture of four stereoisomers due to the two adjacent stereogenic centers in the molecule, complicating further development in the preclinical setting. This work describes the isolation and characterization of the individual isomers of 1 and shows that these display stereospecific pharmacokinetic and pharmacodynamic features. In addition, we present a stereoselective synthesis of the active isomers, providing a basis for further development of this compound series into a novel experimental therapeutic for glioblastoma.

  • 19.
    Svärd, M
    et al.
    Synthesis and Solid State Pharmaceutical Centre, Department of Chemical and Environmental Science, Materials and Surface Science Institute, University of Limerick; Department of Chemical Engineering and Technology, KTH Royal Institute of Technology.
    Hjorth, T
    Department of Chemical Engineering and Technology, KTH Royal Institute of Technology.
    Bohlin, Martin
    RISE, SP – Sveriges Tekniska Forskningsinstitut, SP Process Development.
    Rasmuson, AC
    Synthesis and Solid State Pharmaceutical Centre, Department of Chemical and Environmental Science, Materials and Surface Science Institute, University of Limerick; Department of Chemical Engineering and Technology, KTH Royal Institute of Technology.
    Calorimetric Properties and Solubility in Five Pure Organic Solvents of N-Methyl- d -Glucamine (Meglumine)2016In: Journal of Chemical and Engineering Data, ISSN 0021-9568, E-ISSN 1520-5134, Vol. 61, no 3, p. 1199-1204Article in journal (Refereed)
    Abstract [en]

    The solid-liquid solubility of the title compound has been measured by a gravimetric method in five pure organic solvents over the temperature range (283 to 323) K. The melting temperature and associated enthalpy of fusion have been determined by differential scanning calorimetry (DSC), and the heat capacity of the solid and the melt have been determined over a range of temperatures by means of temperature-modulated DSC. Melting data and the extrapolated difference in heat capacity between the melt and the solid have been used to calculate the Gibbs energy, enthalpy, and entropy of fusion and the ideal solubility from below ambient temperature to the melting point. On the basis of estimated activity coefficients at equilibrium, solutions in all the five solvents are shown to exhibit positive deviation from Raoult's law. The highest mole fraction solubility is observed in methanol, and all van't Hoff solubility curves are nonlinear. Solubility data is well correlated by a recently proposed semiempirical regression model. © 2016 American Chemical Society.

1 - 19 of 19
CiteExportLink to result list
Permanent link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
v. 2.35.4