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  • 401.
    Almgren, K
    et al.
    RISE, SP – Sveriges Tekniska Forskningsinstitut, SP Sveriges tekniska forskningsinstitut, SIK – Svenska institutet för konserveringsforskning.
    Rappe, A
    Fredholm, L
    Inverkan av lagring och termostabilisering i olja på konsumtionsäggens kvalitet1959Report (Refereed)
  • 402.
    Almgren, Karin M.
    et al.
    RISE, STFI-Packforsk.
    Gamstedt, E. Kristofer
    RISE, STFI-Packforsk.
    Berthold, Fredrik
    RISE, STFI-Packforsk.
    Lindström, Mikael
    RISE, STFI-Packforsk.
    Moisture uptake and hygroexpansion of wood fiber composite materials with polylactide and polypropylene matrix materials2009In: Polymer Composites, ISSN 0272-8397, E-ISSN 1548-0569, Vol. 30, no 12, p. 1809-1816Article in journal (Refereed)
    Abstract [en]

    Effects of butantetracarboxylic acid (BTCA) modification, choice of matrix, and fiber volume fraction on hygroexpansion of wood fiber composites have been investigated. Untreated reference wood fibers and BTCA-modified fibers were used as reinforcement in composites with matrices composed of polylactic acid (PLA), polypropylene (PP), or a mixture thereof. The crosslinking BTCA modification reduced the out-of- plane hygroexpansion of PLA and PLA/PP composites, under water-immersed and humid conditions, whereas the swelling increased when PP was used as matrix material. This is explained by difficulties for the BTCA- modified fibers to adhere to the PP matrix. Fiber volume fraction was the most important parameter as regards out-of-plane hygroexpansion, with a high-fiber fraction leading to large hygroexpansion. Fiber-matrix wettability during processing and consolidation also showed to have a large impact on the dimensional stability and moisture uptake.

  • 403.
    Almgren, Karin M.
    et al.
    RISE, STFI-Packforsk.
    Gamstedt, E. Kristofer
    RISE, STFI-Packforsk.
    Nygård, P.
    Malmberg, F.
    Lindblad, J.
    Lindström, Mikael
    RISE, STFI-Packforsk.
    Role of fibre-fibre and fibre-matrix adhesion in stress transfer in composites made from resin-impregnated paper sheets2009In: International Journal of Adhesion and Adhesives, ISSN 0143-7496, E-ISSN 1879-0127, Vol. 29, no 5, p. 551-557Article in journal (Refereed)
    Abstract [en]

    Paper-reinforced plastics are gaining increased interest as packaging materials, where mechanical properties are of great importance. Strength and stress transfer in paper sheets are controlled by fibre-fibre bonds. In paper-reinforced plastics, where the sheet is impregnated with a polymer resin, other stress-transfer mechanisms may be more important. The influence of fibre-fibre bonds on the strength of paper-reinforced plastics was therefore investigated. Paper sheets with different degrees of fibre-fibre bonding were manufactured and used as reinforcement in a polymeric matrix. Image analysis tools were used to verify that the difference in the degree of fibre-fibre bonding had been preserved in the composite materials. Strength and stiffness of the composites were experimentally determined and showed no correlation to the degree of fibre-fibre bonding, in contrast to the behaviour of unimpregnated paper sheets. The degree of fibre-fibre bonding is therefore believed to have little importance in this type of material, where stress is mainly transferred through the fibre-matrix interface.

  • 404.
    Almgren, K.M.
    et al.
    RISE, Innventia.
    Gamstedt, E.K.
    RISE, Innventia.
    Characterization of interfacial stress transfer ability by dynamic mechanical analysis of cellulose fiber based composite materials2010In: Composite interfaces (Print), ISSN 0927-6440, E-ISSN 1568-5543, Vol. 17, no 9, p. 845-861Article in journal (Refereed)
    Abstract [en]

    The stress transfer ability at the fiber-matrix interface of wood fiber composites is known to affect the mechanical properties of the composite. The evaluation of interface properties at the level of individual fibers is however difficult due to the small dimensions and variability of the fibers. The dynamical mechanical properties of composite and constituents, in this case wood fibers and polylactide matrix, was here used together with micromechanical modeling to quantify the stress transfer efficiency at the fiber-matrix interface. To illustrate the methodology, a parameter quantifying the degree of imperfection at the interface was identified by inverse modeling using a micromechanical viscoelastic general self-consistent model with an imperfect interface together with laminate analogy on the composite level. The effect of moisture was assessed by comparison with experimental data from dynamic mechanical analysis in dry and moist state. For the wood fiber reinforced polylactide, the model shows that moisture absorption led to softening and mechanical dissipation in the hydrophilic wood fibers and biothermoplastic matrix, rather than loss of interfacial stress transfer ability.

  • 405.
    Almgren, Knut
    SIK – Svenska institutet för konserveringsforskning.
    Försök att stabilisera äggets kvalitet genom kombination av olika konserverande åtgärder1953In: Kungliga Lantbruksakademiens Tidskrift, Vol. 92, no 6, p. 474-491Article in journal (Other academic)
  • 406.
    Almgren, Knut
    SIK – Svenska institutet för konserveringsforskning.
    Gurkinläggningar - pickles eller quickles?1952In: Svensk Jordbruksforskning, Årsbok, p. 249-259Article in journal (Other academic)
  • 407.
    Almgren, Knut
    SIK – Svenska institutet för konserveringsforskning.
    Minska förslusterna vid ägglagring1953In: Lantmannen, Vol. 37, no 26, p. 625-626Article in journal (Other academic)
  • 408.
    Almgren, Knut
    SIK – Svenska institutet för konserveringsforskning.
    Moderna ägglagringsmetoder1949In: Svensk Jordbruksforskning, Årsbok, p. 217-226Article in journal (Other academic)
  • 409.
    Almgren, Knut
    SIK – Svenska institutet för konserveringsforskning.
    Pasteurization of dirty eggs in oil after washing1956In: Bulletin de l' Institute International du Froid, Annexe, Vol. 1, p. 37-41Article in journal (Other academic)
  • 410.
    Almgren, Knut
    SIK – Svenska institutet för konserveringsforskning.
    Stabilitetsfrågor vid lagring av ägg1954In: Kylteknisk Tidskrift, Vol. 13, no 4, p. 50-54Article in journal (Other academic)
  • 411.
    Almgren, Knut
    SIK – Svenska institutet för konserveringsforskning.
    Vaxning av frukt och grönsaker1956In: Skogs- och Lantbruksakademiens tidskrift, Vol. 95, no 42130, p. 275-318Article in journal (Other academic)
  • 412.
    Almgren, Knut
    SIK – Svenska institutet för konserveringsforskning.
    Äggets kvalitet och hantering1951In: Svensk Jordbruksforskning, Årsbok, p. 245-252Article in journal (Other academic)
  • 413.
    Almgren, Knut
    SIK – Svenska institutet för konserveringsforskning.
    Ägglagringens problem och metoder1949In: Kungliga Lantbruksakademiens Tidskrift, Vol. 88, p. 52-106Article in journal (Other academic)
  • 414.
    Almgren, P
    RISE, SP – Sveriges Tekniska Forskningsinstitut, SP Sveriges tekniska forskningsinstitut, TräteknikCentrum , Trätek.
    Tvärkraftsbelastade spikar i ändträ provningsrapport1987Report (Other academic)
    Abstract [sv]

    Provningar för dimensionering av olika konstruktioner kräver tid och omtanke. I dagens byggnorm, SBN 1980, finns inga angivna tillåtna värden för spikar i ändträ, varken när det gäller utdragskraft eller tvärkraft. I praktiken utnyttjas ofta spikar i ändträ för att ta upp tvärkraften. Man vet av erfarenhet att det ger en avsevärd hållfasthet åt förbanden. Ingen riktig dokumentation av hur stor hållkraften är har dock funnits. En inledande studie har nu gjorts av spikars hållkraft i ändträ. Det karakteristiska värdet (ett av hållfasthetsspridningen påverkat fraktilvärde, lägre än medelvärdet) för spik i ändträ visade sig kunna sättas till ca 60 % av motsvarande värde för spik slagen vinkelrätt fibrerna. Värdet kan dock inte anges utan förbehåll innan ytterligare studier gjorts och regler för hur provningen skall utföras utarbetats.

  • 415.
    Almhöjd, Ulrika S.
    et al.
    Sahlgrenska Academy, Sweden.
    Lingström, Peter
    Sahlgrenska Academy, Sweden.
    Nilsson, Åke
    Sahlgrenska Academy, Sweden.
    Noren, Jörgen G.
    Sahlgrenska Academy, Sweden.
    Siljeström, Silje
    RISE - Research Institutes of Sweden, Bioscience and Materials, Chemistry and Materials.
    ֖stlund, Å.
    RISE - Research Institutes of Sweden, Bioeconomy, Biorefinery and Energy.
    Bernin, D.
    University of Gothenburg, Sweden.
    Molecular Insights into Covalently Stained Carious Dentine Using Solid-State NMR and ToF-SIMS2017In: Caries Research, ISSN 0008-6568, E-ISSN 1421-976X, Vol. 51, no 3, p. 255-263Article in journal (Refereed)
    Abstract [en]

    Dyes currently used to stain carious dentine have a limited capacity to discriminate normal dentine from carious dentine, which may result in overexcavation. Consequently, finding a selective dye is still a challenge. However, there is evidence that hydrazine-based dyes, via covalent bonds to functional groups, bind specifically to carious dentine. The aim of this study was to investigate the possible formation of covalent bonds between carious dentine and 15N2-hydrazine and the hydrazine-based dye, 15N2-labelled Lucifer Yellow, respectively. Powdered dentine from extracted carious and normal teeth was exposed to the dyes, and the staining reactions were analysed using time-of-flight secondary ion mass spectrometry (ToF-SIMS), solid-state 13C-labelled nuclear magnetic resonance (NMR) and 15N-NMR spectroscopy. The results showed that 15N2-hydrazine and 15N2-labelled Lucifer Yellow both bind to carious dentine but not to normal dentine. It can thus be concluded that hydrazine-based dyes can be used to stain carious dentine and leave normal dentine unstained.

  • 416. Alminger Larsson, Marie
    et al.
    Eklund-Jonsson, Charlotte
    SIK – Institutet för livsmedel och bioteknik.
    Kidman, Siw
    SIK – Institutet för livsmedel och bioteknik.
    Langton, Maud
    SIK – Institutet för livsmedel och bioteknik.
    Starch Microstructure and Starch Hydrolysis in Barley and Oat Tempe during in Vitro Digestion2012In: Food Digestion, ISSN 1869-1978, E-ISSN 1869-1986, Vol. 3, no 42007, p. 53-62Article in journal (Refereed)
    Abstract [en]

    Various botanical and structural characteristics of starchy foods are considered to modify the rate of starch digestion and the glycaemic responses in humans. The main objective of the study was to examine the impact of fermented barley and oat microstructure on the rate of in vitro starch hydrolysis. A dynamic gastrointestinal model was used to estimate the degree of starch hydrolysis during in vitro digestion of fermented whole grain cereal meals. Light microscopy and confocal laser scanning microscopy were used to study the microstructural changes. In parallel to the in vitro studies, the impact of fermented barley and oats on postprandial plasma glucose responses was evaluated in a human study. Micrographs were taken during in vitro digestion experiments with fermented whole grains and compared with micrographs of boiled barley (undigested). Images showed that most of the oat starch granules were degraded after 120 min of digestion, whereas barley starch granules were less degraded, even after 180 min of digestion. The findings were confirmed by faster starch hydrolysis from the fermented oat meal, measured as maltose generated during in vitro digestion. The area under the curve (AUC) was calculated from the plotted maltose curves of the meals. AUC for barley tempe (266 ± 33) was 40 % of the AUC for oat tempe (663 ± 8) and significantly different (p < 0.007) from AUC oat tempe. The in vitro data closely resembled the AUCs for plasma glucose from the parallel human study. In terms of glucose response, the mean AUC for barley tempe was 46 % of the AUC for oat tempe in the human study. The agreement between the in vitro and in vivo data indicates the potential of the in vitro method as a tool to predict the rate of starch degradation of cereal products. © 2012 Springer Science+Business Media New York.

  • 417.
    Almquist, Per
    et al.
    RISE, Swedish ICT, SICS. IAM.
    Karlgren, Jussi
    RISE, Swedish ICT, SICS. IAM.
    Experiments to investigate the utility of nearest neighbour metrics based on linguistically informed features for detecting textual plagiarism2011Conference paper (Refereed)
    Abstract [en]

    Plagiarism detection is a challenge for linguistic models — most current implemented models use simple occurrence statistics for linguistic items. In this paper we report two experiments related to plagiarism detection where we use a model for distributional semantics and of sentence stylistics to compare sentence by sentence the likelihood of a text being partly plagiarised. The result of the comparison are displayed for visual inspection by a plagiarism assessor.

  • 418. Almstrand, A-C
    et al.
    Ljungström, E
    Lausmaa, J
    YKI – Ytkemiska institutet.
    Bake, B
    Sjövall, P
    YKI – Ytkemiska institutet.
    Olin, A-C
    Airway Monitoring by Collection and Mass Specrometric Analysis of Exhaled Particles2009In: Analytical Chemistry, ISSN 0003-2700, E-ISSN 1520-6882, Vol. 81, no 2, p. 662-668Article in journal (Refereed)
    Abstract [en]

    We describe a new method for simultaneously collecting particles in exhaled air for subsequent chemical analysis and measuring their size distribution. After forced exhalation, particles were counted and collected in spots on silicon wafers with a cascade impactor. Several phospholipids were identified by time-of-flight secondary ion mass spectrometric analysis of the collected spots, suggesting that the particles originated from the lower airways. The amount of particles collected in ten exhalations was sufficient for characterizing the phospholipid composition. The feasibility of the technique in respiratory research is demonstrated by analysis of the phospholipid composition of exhaled particles from healthy controls, patients with asthma, and patients with cystic fibrosis. We believe this technology will be useful for monitoring patients with respiratory disease and has a high potential to detect new biomarkers in exhaled air.

  • 419. Almström, Peter
    et al.
    Andersson, Carin
    Lund University, Sweden.
    Ericsson Öberg, Anna
    Hammersberg, Peter
    Kurdve, Martin
    RISE - Research Institutes of Sweden, Swerea, Swerea IVF.
    Landström, Anna
    Shahbazi, Sasha
    Mälardalen University, Sweden.
    Wiktorsson, Magnus
    Mälardalen University, Sweden.
    Windmark, Christina
    Lund University, Sweden.
    Winroth, Mats
    Zackrisson, Mats
    RISE - Research Institutes of Sweden, Swerea, Swerea IVF, Energi och miljö.
    Sustainable and Resource Efficient Business Performance Measurement Systems: - The Handbook2017Report (Other academic)
  • 420.
    Alonso, Juan
    et al.
    RISE - Research Institutes of Sweden, ICT, SICS.
    Abrahamsson, Henrik
    RISE, Swedish ICT, SICS, Decisions, Networks and Analytics lab.
    Ahlgren, Bengt
    RISE, Swedish ICT, SICS, Decisions, Networks and Analytics lab.
    Andersson, Anders
    RISE - Research Institutes of Sweden, ICT, SICS.
    Kreuger, Per
    RISE, Swedish ICT, SICS, Decisions, Networks and Analytics lab.
    Objective Functions for Balance in Traffic Engineering2002Report (Other academic)
    Abstract [en]

    We prove a result concerning objective functions that can be used to obtain efficient and balanced solutions to the multi-commodity network flow problem. This type of solution is of interest when routing traffic in the Internet. A particular case of the result proved here (see Corollary 2 below) was stated without proof in a previous paper.

  • 421.
    Alonso, Juan
    et al.
    RISE, Swedish ICT, SICS.
    Dunkels, Adam
    RISE, Swedish ICT, SICS.
    Voigt, Thiemo
    RISE, Swedish ICT, SICS, Computer Systems Laboratory.
    Bounds on the energy consumption of routings in wireless sensor networks2004Conference paper (Refereed)
  • 422.
    Alonso, Juan
    et al.
    RISE - Research Institutes of Sweden, ICT, SICS.
    Dunkels, Adam
    RISE, Swedish ICT, SICS.
    Voigt, Thiemo
    RISE, Swedish ICT, SICS, Computer Systems Laboratory.
    Bounds on the Energy Consumption of Routings in Wireless Sensor Networks2003Report (Other academic)
    Abstract [en]

    Energy is one of the most important resources in wireless sensor networks. We use an idealized mathematical model to study the impact of routing on energy consumption. Our results are very general and, within the assumptions listed in Section 2, apply to arbitrary topologies, routings and radio energy models. We find bounds on the minimal and maximal energy routings will consume, and use them to bound the lifetime of the network. The bounds are sharp, and can be achieved in many situations of interest. We illustrate the theory with some examples.

  • 423. Alonso, Juan
    et al.
    Dunkels, Adam
    RISE, Swedish ICT, SICS.
    Voigt, Thiemo
    RISE, Swedish ICT, SICS, Computer Systems Laboratory.
    Bounds on the Lifetime of Wireless Sensor Networks2004Report (Other academic)
    Abstract [en]

    Energy is one of the most important resources in wireless sensor networks. We use an idealized mathematical model to study the energy consumption under all possible routings. Our results are very general and, within the assumptions listed in Section 2, apply to arbitrary topologies, routings and radio energy models. We find bounds on the minimal and maximal energy routings will consume, and use them to bound the lifetime of the network. The bounds are sharp, and we show that they are achievable in many situations of interest. We give some examples, and apply the theory to the problem of covering a given square region with the most efficient member of a family of increasingly more dense square-lattice sensor networks. Finally, we use simulations to test these results in a more realistic scenario, where packet loss can occur.

  • 424.
    Alonso, Juan
    et al.
    RISE, Swedish ICT, SICS.
    Hermiller, Susan M.
    Homological finite derivation type2003In: International journal of algebra and computation, ISSN 0218-1967, Vol. 13, no 3, p. 341-359Article in journal (Refereed)
    Abstract [en]

    In 1987, Squier defined the notion of finite derivation type for a finitely presented monoid. To do this, he associated a 2-complex to the presentation. The monoid then has finite derivation type if, modulo the action of the free monoid ring, the 1-dimensional homotopy of this complex is finitely generated. Cremanns and Otto showed that finite derivation type implies the homological finiteness condition left FP3, and when the monoid is a group, these two properties are equivalent. In this paper we define a new version of finite derivation type, based on homological information, together with an extension of this finite derivation type to higher dimensions, and show connections to homological type FPn for both monoids and groups.

  • 425. Alonso, Juan
    et al.
    Voigt, Thiemo
    RISE, Swedish ICT, SICS, Computer Systems Laboratory.
    Varshney, Ambuj
    Bounds on the Lifetime of WSNs2013Conference paper (Refereed)
  • 426. Alonso, Omar
    et al.
    Kamps, Jaap
    Karlgren, Jussi
    RISE, Swedish ICT, SICS.
    Fourth workshop on Exploiting Semantic Annotations in Information Retrieval (ESAIR)2011Conference paper (Refereed)
    Abstract [en]

    There is an increasing amount of structure on the Web as a result of modern Web languages, user tagging and annotation, and emerg- ing robust NLP tools. These meaningful, semantic, annotations hold the promise to significantly enhance information access, by enhancing the depth of analysis of today’s systems. Currently, we have only started exploring the possibilities and only begin to un- derstand how these valuable semantic cues can be put to fruitful use. Unleashing the potential of semantic annotations requires us to think outside the box, by combining the insights of natural lan- guage processing (NLP) to go beyond bags of words, the insights of databases (DB) to use structure efficiently even when aggregating over millions of records, the insights of information retrieval (IR) in effective goal-directed search and evaluation, and the insights of knowledge management (KM) to get grips on the greater whole. This workshop aims to bring together researchers from these dif- ferent disciplines and work together on one of the greatest chal- lenges in the years to come. The desired result of the workshop will be to gain concrete insight into the potential of semantic an- notations, and in concrete steps to take this research forward; to synchronize related research happening in NLP, DB, IR, and KM, in ways that combine the strengths of each discipline; and to have a lively, interactive workshop where every participant contributes actively and which inspires attendees to think freely and creatively, working towards a common goal.

  • 427.
    Alonzo, Ylva
    et al.
    RISE, SP – Sveriges Tekniska Forskningsinstitut, SP Energi och Bioekonomi.
    Henriksson, Gunilla
    RISE, SP – Sveriges Tekniska Forskningsinstitut, SP Energi och Bioekonomi.
    Rapport från projektet Hästgödsel i kretslopp - Sjuhärad2016Report (Other academic)
  • 428. Alqatawna, Ja´far
    et al.
    Rissanen, Erik
    RISE, Swedish ICT, SICS.
    Sadighi, Babak
    RISE, Swedish ICT, SICS.
    Overriding of Access Control in XACML2007In: Proceedings of the Eighth IEEE International Workshop on Policies for Distributed Systems and Networks, 2007, 1, , p. 9Conference paper (Refereed)
    Abstract [en]

    Most access control mechanisms focus on how to define the rights of users in a precise way to prevent any violation of the access control policy of an organization. However, in many cases it is hard to predefine all access needs, or even to express them in machine readable form. One example of such a situation is an emergency case which may not be predictable and would be hard to express as a machine readable condition. Discretionary overriding of access control is one way for handling such hard to define and unanticipated situations where availability is critical. The override mechanism gives the subject of the access control policy the possibility to override a denied decision, and if the subject should confirm the override, the access will be logged for special auditing. XACML, the eXtensible Access Control Markup Language, provides a standardized access control policy language for expressing access control policies. This paper introduces a discretionary overriding mechanism in XACML. We do so by means of XACML obligations and also define a general obligation combining mechanism.

  • 429.
    Al-Ramahi, Nawres
    et al.
    Luleå University of Technology, Sweden ; Middle Technical University, Iraq.
    Joffe, Roberts
    RISE - Research Institutes of Sweden, Swerea, Swerea SICOMP. Luleå University of Technology, Sweden .
    Varna, Janis
    Luleå University of Technology, Sweden .
    Investigation of end and edge effects on results of numerical simulation of single lap adhesive joint with non-linear materials2018In: International Journal of Adhesion and Adhesives, ISSN 0143-7496, E-ISSN 1879-0127, Vol. 87, p. 191-204Article in journal (Refereed)
    Abstract [en]

    This paper presents systematic numerical study of stresses in the adhesive of a single-lap joint with the objective to improve understanding of the main material and geometrical parameters determining performance of adhesive joints. For this purpose a 3D model as well as 2D model, optimized with respect to the computational efficiency by use of novel displacement coupling conditions able to correctly represent monoclinic materials (off-axis layers of composite laminates), are employed. The model accounts for non-linearity of materials (adherend and adhesive) as well as geometrical non-linearity. The parameters of geometry of the joint are normalized with respect to the dimensions of adhesive (e.g. thickness) thus making analysis of results more general and applicable to wide range of different joints. Optimal geometry of the single-lap joint allowing to separate edge effect from end effects is selected based on results of the parametric analysis by using peel and shear stress distributions in the adhesive layer as a criterion. Three different types of single lap joint with similar and dissimilar (hybrid) materials are considered in this study: a) metal-metal; b) composite-composite; c) composite-metal. In case of composite laminates, four lay-ups are evaluated: uni-directional ([08]T and [908]T) and quasi-isotropic laminates ([0/45/90/-45]S and [90/45/0/-45]S). The influence of the abovementioned parameters on peel and shear stress distributions in the adhesive layer is examined carefully and mechanical parameters governing the stress concentrations in the joint have been identified, this dependence can be described by simple but accurate fitting function. The effect of the used material model (linear vs non-linear) on results is also demonstrated.

  • 430. Alriksson, B.
    et al.
    Rose, S. H.
    Van Zyl, W. H.
    Sjöde, A.
    Nilvebrant, N. -O
    RISE, STFI-Packforsk.
    Jönsson, L. J.
    Cellulase production from spent lignocellulose hydrolysates by recombinant aspergillus niger2009In: Applied and Environmental Microbiology, ISSN 0099-2240, E-ISSN 1098-5336, Vol. 75, no 8, p. 2366-2374Article in journal (Refereed)
    Abstract [en]

    A recombinant Aspergillus niger strain expressing the Hypocrea jecorina endoglucanase Cel7B was grown on spent hydrolysates (stillage) from sugarcane bagasse and spruce wood. The spent hydrolysates served as excellent growth media for the Cel7B-producing strain, A. niger D15[egI], which displayed higher endoglucanase activities in the spent hydrolysates than in standard medium with a comparable monosaccharide content (e.g., 2,100 nkat/ml in spent bagasse hydrolysate compared to 480 nkat/ml in standard glucose-based medium). In addition, A. niger D15[egI] was also able to consume or convert other lignocellulose-derived compounds, such as acetic acid, furan aldehydes, and phenolic compounds, which are recognized as inhibitors of yeast during ethanolic fermentation. The results indicate that enzymes can be produced from the stillage stream as a high-value coproduct in secondgeneration bioethanol plants in a way that also facilitates recirculation of process water.

  • 431.
    Alriksson, Björn
    RISE, SP – Sveriges Tekniska Forskningsinstitut, SP Processum.
    Production of cellulosic ethanol and enzyme from waste fiber sludge using SSF, recycling of hydrolytic enzymes and yeast, and recombinant cellulase-producing Aspergillus niger2015In: Journal of Industrial Microbiology & Biotechnology, ISSN 1367-5435, E-ISSN 1476-5535, Vol. 41, no 8, p. 1191-1200Article in journal (Refereed)
  • 432.
    Alriksson, Björn
    et al.
    RISE, SP – Sveriges Tekniska Forskningsinstitut, SP Processum.
    Cavka, Adnan
    Jönsson, Leif J.
    Improving the fermentability of enzymatic hydrolysates of lignocellulose through chemical in-situ detoxification with reducing agents2011In: Bioresource Technology, ISSN 0960-8524, E-ISSN 1873-2976, Vol. 102, no 2, p. 1254-1263Article in journal (Refereed)
    Abstract [en]

    Inhibitory lignocellulose hydrolysates were treated with the reducing agents dithionite and sulfite to achieve improved fermentability. Addition of these reducing agents (in the concentration range 5.0-17.5mM) to enzymatic hydrolysates of spruce wood or sugarcane bagasse improved processes based on both SHF (simultaneous hydrolysis and fermentation) and SSF (simultaneous saccharification and fermentation). The approach was exemplified in ethanolic fermentations with Saccharomyces cerevisiae and by using hydrolysates with sugar concentrations &gt;100g/L (for SHF) and with 10% dry-matter content (for SSF). In the SHF experiments, treatments with dithionite raised the ethanol productivities of the spruce hydrolysate from 0.2 to 2.5g×L -1×h -1 and of the bagasse hydrolysate from 0.9 to 3.9g×L -1×h -1, values even higher than those of fermentations with reference sugar solutions without inhibitors. Benefits of the approach include that the addition of the reducing agent can be made in-situ directly in the fermentation vessel, that the treatment can be performed at a temperature and pH suitable for fermentation, and that the treatment results in dramatically improved fermentability without degradation of fermentable sugars. The many benefits and the simplicity of the approach offer a new way to achieve more efficient manufacture of fermentation products from lignocellulose hydrolysates. © 2010 Elsevier Ltd.

  • 433. Alriksson, Björn
    et al.
    Eskilsson, Martin
    Johansson, Emma
    Lapidot, Shaul
    Norström, Markus
    Schultz-Eklund, Ola
    Shkedi, Yoram
    Svedberg, Anna
    Svensson, Stefan
    Swerin, Agne
    RISE, SP – Sveriges Tekniska Forskningsinstitut, SP Kemi Material och Ytor, Material och ytteknik.
    Europe’s first pilot facility for cellulose nanocrystals (CNC)2016In: Annual Surface and Materials Chemistry Symposium and Materials for tomorrow, ASMCS 2016, November 8-10, 2016, Gothenburg, Sweden, 2016Conference paper (Refereed)
  • 434.
    Alriksson, Björn
    et al.
    RISE, SP – Sveriges Tekniska Forskningsinstitut, SP Processum.
    Hörnberg, Andreas
    RISE, SP – Sveriges Tekniska Forskningsinstitut, SP Processum.
    Fish feed from wood2014In: Cellulose Chemistry and Technology, ISSN 0576-9787, Vol. 48, no 9-10, p. 843-848Article in journal (Refereed)
  • 435.
    Alriksson, Björn
    et al.
    RISE, SP – Sveriges Tekniska Forskningsinstitut, SP Processum.
    Hörnberg, Andreas
    Gudnason, Asgeir Eirikur
    Knobloch, Stephen
    Arnason, Jon
    Johannsson, Ragnar
    Fish feed from wood2014In: Cellulose Chemistry and Technology, ISSN 0576-9787, Vol. 48, p. 843-848Article in journal (Refereed)
    Abstract [en]

    Increased demand of fish in combination with overexploitation of the fish stocks of the oceans has led to an increased production of fish through aquaculture. Today, fishmeal is the main protein source in fish feed for most aquaculture species. However, fishmeal is soon expected to fall short of demand as its production is associated with environmental problems. This shortage must therefore be met by sustainable alternative protein sources. Protein-rich microorganisms (i.e. Single cell protein) is an interesting option as a fishmeal substitute in fish feed which, in addition, can be produced as an important co-product in wood-based biorefineries. In the current study, four different microorganisms were cultivated on five different residual streams from Swedish wood-based biorefineries. Screening experiments were carried out in shake flasks, optimization experiments in benchtop bioreactors, and scale-up experiments were performed in a 50-litre pilot bioreactor. In addition, a demo-scale experiment was carried out in the Swedish Biorefinery Demo Plant. Microbial biomass from the scale-up experiments was collected and used for production of different fish feed formulations which, in turn, were used in feeding trials of the freshwater fish Tilapia. Fishes fed with feed, in which part of the fishmeal had been substituted with Single cell protein, showed similar or better growth than fishes fed with a fishmeal-based control feed.

  • 436.
    Alsanius, Beatrix
    et al.
    SLU Swedish University of Agricultural Sciences, Sweden.
    Löfström, Charlotta
    RISE - Research Institutes of Sweden, Bioscience and Materials, Agrifood and Bioscience.
    Vattenrening för ökad hygien vid odling av frilandsgrönsaker och bär2017Other (Other (popular science, discussion, etc.))
    Abstract [sv]

    Under senare år har ett flertal utbrottmed magsjuka kopplats till konsumtionav grönsaker, frukt och bär. Sjukdomsframkallandebakterier och virus, såsomnorovirus, Salmonella, toxinproducerandeE. coli, Campylobacter och Listeria. kanspridas från bevattningsvatten via grö-dan till människor och orsaka sjukdom.Smittat bevattningsvatten kan därförförorena frilandsproducerade grönsakeroch bär. Det är alltås viktigt att hakontroll på bevattningsvattnets kvalitet.Dessutom är det viktigt att känna tillvilken typ av kultur som vattnet skaanvändas till, eftersom risken för vidaresmitta till människor varierar mellanolika typer av kulturer. T.ex. är det störrerisk att använda kontaminerat vatten tillkulturer som äts råa utan uppvärmninghos livsmedelsproducenten eller konsument,eftersom det då inte finns nå-gon möjlighet att avdöda de oönskademikroorganismerna i ett efterföljandesteg. Genom rätt hantering och adekvatbehandling av bevattningsvattnetkan dess hygieniska kvalitet förbättras.Ibland finns det möjlighet för odlarenatt byta vattenkälla, men då detta inte ärpraktiskt möjligt kan det kontamineradevattnet renas innan bevattning. I dettafaktablad beskrivs två grundläggandetekniker för rening av bevattningsvattenvid frilandsproduktion, nämligen fotokemi(fotokatalys, UV) och filtrering(mekanisk filtrering, långsamfiltrering).Dessa används för att minska risken försmittspridning med bevattningsvattnet.

  • 437.
    Alsbjer, Markus
    et al.
    SP - Sveriges Tekniska Forskningsinstitut / Energiteknik (ET).
    Lindahl, Markus
    SP - Sveriges Tekniska Forskningsinstitut / Energiteknik (ET).
    Axell, Monica
    SP - Sveriges Tekniska Forskningsinstitut / Energiteknik (ET).
    The potential for increased primary energy efficiensy and reduces CO2 emissions by DHC2011Report (Refereed)
  • 438. Alshawi, Hiyan
    et al.
    Brown, Carl
    RISE - Research Institutes of Sweden, ICT, SICS.
    Carter, David
    Gambäck, Björn
    RISE, Swedish ICT, SICS.
    Pulman, Steve
    Rayner, Manny
    RISE - Research Institutes of Sweden, ICT, SICS.
    Bilingual conversation interpreter : a prototype interactive message translator. Final report1991Report (Other academic)
    Abstract [en]

    This document is the final report for a research project aimed at producing a prototype system for on-line translation of typed dialogues between speakers of different natural languages. The work was carried out jointly by SICS and SRI Cambridge. The resulting prototype system (called Billingual Conversation Interpreter, or BCI) translates between english and Swedish in both directions.The Major components of the BCI are two copies of the SRI Core Language Engine, equipped with English and Swedish grammars respectively. These are linked by the transfer and disambiguation components. Translation takes place by analyzing the source-language sentence into Quasi Logical Form ( QLF), a linguistically motivated logical representation, transferring this into a target-language QLF, and generating a target-language sentence. When ambiguities occur that cannot be resolved automatically, they are clarified by Querying the appropriate user. The clarification dialogue presupposes no knowledge of either linguistics or the other language. The prototype system has a broad grammatical coverage, a initial vocabulary of about 1000 words together with vocabulary expansion tools, and a set of English-Swedish transfer rules. The formalism developed for coding this linguistic information make it relatively easy to extend the system. We believe that the project was successful in demonstrating the feasibility of using these techniques for interactive translation applications, and provides a sound basis for development of a large scale message translator system with potential for commercial exploitation.The main sections of this report are the following: * A non-technical introduction, summarizing the BCI's design , and containing a sample session. * An overview of the Swedish version of the CLE. * A detailed discussion of the theory and practice of QLF transfer. * A description of the interactive disambiguation method. * Suggestions for possible follow-on projects aimed in the direction of practically usable commercial systems.

  • 439. Alshawi, Hiyan
    et al.
    Carter, David
    Gambäck, Björn
    RISE, Swedish ICT, SICS.
    Pulman, Steve
    Rayner, Manny
    RISE - Research Institutes of Sweden, ICT, SICS.
    Transfer through quasi logical form - A new approach to machine translation1991Report (Other academic)
    Abstract [en]

    This Document is an introduction to a research project aimed at producing a prototype system for on-line translation of typed dialogues between speakers of different natural languages. The work was carried out jointly by SICS and SRI Cambridge. The resulting prototype system (called Billingual Conversation Interpreter, or BCI) translates between English and Swedish in both Directions. The major components of the BCI are two copies of the SRI Core Language Engine, equipped with English and Swedish grammars respectively. These are linked by the transfer and disambiguation components. Translation takes place by analyzing the source-language sentence into Quasi Logical Form (QLF), a linguistically motivated logical representation, transferring this onto a target-language QLF, and generating a target-language sentence. We believe that the project was successful in demonstrating the feasibility of using these techniques for interactive translation applications, and provides a sound basis for development of a large scale message translator system. The final section of the paper points to several possible follow-on projects aimed in the direction of practically usable commercial systems.

  • 440.
    Al-Shishtawy, Ahmad
    RISE, Swedish ICT, SICS, Computer Systems Laboratory.
    Self-management for large-scale distributed systems2012Doctoral thesis, monograph (Other academic)
    Abstract [en]

    Autonomic computing aims at making computing systems self-managing by using autonomic managers in order to reduce obstacles caused by management complexity. This thesis presents results of research on self-management for large-scale distributed systems. This research was motivated by the increasing complexity of computing systems and their management. In the first part, we present our platform, called Niche, for programming self-managing component-based distributed applications. In our work on Niche, we have faced and addressed the following four challenges in achieving self-management in a dynamic environment characterized by volatile resources and high churn: resource discovery, robust and efficient sensing and actuation, management bottleneck, and scale. We present results of our research on addressing the above challenges. Niche implements the autonomic computing architecture, proposed by IBM, in a fully decentralized way. Niche supports a network-transparent view of the system architecture simplifying the design of distributed self-management. Niche provides a concise and expressive API for self-management. The implementation of the platform relies on the scalability and robustness of structured overlay networks. We proceed by presenting a methodology for designing the management part of a distributed self-managing application. We define design steps that include partitioning of management functions and orchestration of multiple autonomic managers. In the second part, we discuss robustness of management and data consistency, which are necessary in a distributed system. Dealing with the effect of churn on management increases the complexity of the management logic and thus makes its development time consuming and error prone. We propose the abstraction of Robust Management Elements, which are able to heal themselves under continuous churn. Our approach is based on replicating a management element using finite state machine replication with a reconfigurable replica set. Our algorithm automates the reconfiguration (migration) of the replica set in order to tolerate continuous churn. For data consistency, we propose a majority-based distributed key-value store supporting multiple consistency levels that is based on a peer-to-peer network. The store enables the tradeoff between high availability and data consistency. Using majority allows avoiding potential drawbacks of a master-based consistency control, namely, a single-point of failure and a potential performance bottleneck. In the third part, we investigate self-management for Cloud-based storage systems with the focus on elasticity control using elements of control theory and machine learning. We have conducted research on a number of different designs of an elasticity controller, including a State-Space feedback controller and a controller that combines feedback and feedforward control. We describe our experience in designing an elasticity controller for a Cloud-based key-value store using state-space model that enables to trade-off performance for cost. We describe the steps in designing an elasticity controller. We continue by presenting the design and evaluation of ElastMan, an elasticity controller for Cloud-based elastic key-value stores that combines feedforward and feedback control.

  • 441.
    Al-Shishtawy, Ahmad
    et al.
    RISE, Swedish ICT, SICS, Computer Systems Laboratory.
    Asif Fayyaz, Muhammad
    Popov, Konstantin
    RISE, Swedish ICT, SICS, Computer Systems Laboratory.
    Vlassov, Vladimir
    Achieving Robust Self-Management for Large-Scale Distributed Applications2010Report (Other academic)
    Abstract [en]

    Autonomic managers are the main architectural building blocks for constructing self-management capabilities of computing systems and applications. One of the major challenges in developing self-managing applications is robustness of management elements which form autonomic managers. We believe that transparent handling of the effects of resource churn (joins/leaves/failures) on management should be an essential feature of a platform for self-managing large-scale dynamic distributed applications, because it facilitates the development of robust autonomic managers and hence improves robustness of self-managing applications. This feature can be achieved by providing a robust management element abstraction that hides churn from the programmer. In this paper, we present a generic approach to achieve robust services that is based on finite state machine replication with dynamic reconfiguration of replica sets. We contribute a decentralized algorithm that maintains the set of nodes hosting service replicas in the presence of churn. We use this approach to implement robust management elements as robust services that can operate despite of churn. Our proposed decentralized algorithm uses peer-to-peer replica placement schemes to automate replicated state machine migration in order to tolerate churn. Our algorithm exploits lookup and failure detection facilities of a structured overlay network for managing the set of active replicas. Using the proposed approach, we can achieve a long running and highly available service, without human intervention, in the presence of resource churn. In order to validate and evaluate our approach, we have implemented a prototype that includes the proposed algorithm.

  • 442.
    Alsholm, Maria
    RISE, SP – Sveriges Tekniska Forskningsinstitut, JTI Institutet för Jordbruks- och Miljöteknik.
    Vegetabiliska oljor som hydrauloljor och deras kompatibilitet med polymera material1996Report (Refereed)
  • 443. Altaf, F.
    et al.
    Johannesson, Lars
    RISE, Swedish ICT, Viktoria.
    Egardt, B.
    On thermal and state-of-charge balancing using cascaded multi-level converters2013In: Journal of Power Electronics (JPE), ISSN 1598-2092, E-ISSN 2093-4718, Vol. 13, no 4, p. 569-583Article in journal (Refereed)
    Abstract [en]

    In this study, the simultaneous use of a multi-level converter (MLC) as a DC-motor drive and as an active battery cell balancer is investigated. MLCs allow each battery cell in a battery pack to be independently switched on and off, thereby enabling the potential non-uniform use of battery cells. By exploiting this property and the brake regeneration phases in the drive cycle, MLCs can balance both the state of charge (SoC) and temperature differences between cells, which are two known causes of battery wear, even without reciprocating the coolant flow inside the pack. The optimal control policy (OP) that considers both battery pack temperature and SoC dynamics is studied in detail based on the assumption that information on the state of each cell, the schedule of reciprocating air flow and the future driving profile are perfectly known. Results show that OP provides significant reductions in temperature and in SoC deviations compared with the uniform use of all cells even with uni-directional coolant flow. Thus, reciprocating coolant flow is a redundant function for a MLC-based cell balancer. A specific contribution of this paper is the derivation of a state-space electro-thermal model of a battery submodule for both uni-directional and reciprocating coolant flows under the switching action of MLC, resulting in OP being derived by the solution of a convex optimization problem.

  • 444. Altaf, F
    et al.
    Johannesson Mårdh, L
    RISE, Swedish ICT, Viktoria.
    Egardt, B
    Feasibility Issues of Using Three-Phase Multilevel Inverter based Cell Balancer in Battery Management System for xEVs2013In: IFAC Proceedings Volumes, Vol. 46, p. 360-, article id 21Article in journal (Refereed)
    Abstract [en]

    The use of a three-phase multilevel converter (MLC) as an integrated cell balancer and motor driver is investigated for three-phase AC applications in EVs/HEVs/PHEVs. The paper analyzed an issue of additional battery losses caused by the flow of reactive and/or harmonic power from each power cell of the three-phase MLC battery system. The paper also investigates the size of shunt capacitor required for compensation of the losses to acceptable level. This study concludes that the size of the required capacitor is too big for the vehicle application unless some other active compensation is used as well. Another practical way to employ the MLC as a cell balancer is to use it in a cascaded connection with the conventional three-phase two-level voltage source inverter however it may not be a cost-effective solution either due to high component count.

  • 445. Altaf, F
    et al.
    Johannesson Mårdh, L
    RISE, Swedish ICT, Viktoria.
    Egardt, B
    On Thermal State-of-Charge Balancing using Cascaded Multilevel Converter2013In: Journal of Power Electronics (JPE), ISSN 1598-2092, E-ISSN 2093-4718, Vol. 13, no 4, p. 569-Article in journal (Refereed)
    Abstract [en]

    Multilevel Converters are studied for simultaneous_x000D_ use as a DC-motor drive active battery cell balancer._x000D_ The Multilevel Converter (MLC) allows to independently switch_x000D_ ON/OFF each battery cell in a battery pack giving the possibility_x000D_ of non-uniform use of the battery cells. By exploiting this_x000D_ property brake regeneration phases in the drive cycle, the_x000D_ MLC has the possibility to balance both State-of-Charge (SoC)_x000D_ temperature differences between the cells, which are two_x000D_ known causes of battery wear, without even reciprocating the_x000D_ coolant flow inside the pack. The optimal control policy (OP )_x000D_ that takes into consideration both the battery pack temperature_x000D_ SoC dynamics is studied in detail based on the assumption_x000D_ of perfect information of the state the future driving. The_x000D_ results show that OP gives significant reduction in temperature_x000D_ SoC deviations compared to uniform use of all the cells even_x000D_ under unidirectional coolant flow. Thus reciprocating coolant flow_x000D_ is a redundant function for MLC based cell balancer. A specific_x000D_ contribution of the paper is the derivation of a state-space electrothermal_x000D_ model of a battery submodule €”for both unidirectional_x000D_ as well as reciprocating coolant flow€” under the switching action_x000D_ of an MLC, formulated in such a way that the OP is given by_x000D_ the solution of a convex optimization problem._x000D_

  • 446. Althammer, Egbert
    et al.
    Schoitsch, Erwin
    Eriksson, Henrik
    RISE, SP – Sveriges Tekniska Forskningsinstitut, SP Elektronik, Pålitliga system.
    Vinter, Jonny
    RISE, SP – Sveriges Tekniska Forskningsinstitut, SP Elektronik, Pålitliga system.
    The DECOS Concept of Generic Safety Cases - a Step Towards Modular Certification Support2009In: 35th Euromicro Conference on Software Engineering and Advanced applications SEAA. Patras, Greece. 2009-08-27--29, 2009Conference paper (Refereed)
  • 447. Althammer, Egbert
    et al.
    Schoitsch, Erwin
    Eriksson, Henrik
    RISE, SP – Sveriges Tekniska Forskningsinstitut, SP Elektronik, Pålitliga system.
    Vinter, Jonny
    RISE, SP – Sveriges Tekniska Forskningsinstitut, SP Elektronik, Pålitliga system.
    Pataticza, Andras
    Csertan, Gy-rgy
    An Open System for Dependable System Validation and Verification Support - The DECOS Generic Test Bench2007Conference paper (Refereed)
  • 448. Althammer, Egbert
    et al.
    Schoitsch, Erwin
    Sonneck, Gerald
    Eriksson, Henrik
    RISE, SP – Sveriges Tekniska Forskningsinstitut, SP Elektronik, Pålitliga system.
    Vinter, Jonny
    RISE, SP – Sveriges Tekniska Forskningsinstitut, SP Elektronik, Pålitliga system.
    Modular Certification Support - the DECOS Concept of Generic Safety Cases2008Conference paper (Other academic)
  • 449.
    Altmann, Brigitte
    et al.
    University of Freiburg, Germany.
    Karygianni, Lamprini
    University of Freiburg, Germany.
    Al-Ahmad, Ali
    University of Freiburg, Germany.
    Butz, Frank
    University of Freiburg, Germany.
    Bächle, Maria
    University of Freiburg, Germany.
    Adolfsson, Erik
    RISE - Research Institutes of Sweden, Swerea, Swerea IVF.
    Fürderer, Tobias
    Courtois, Nicolas
    Palmero, Paola
    Politecnico di Torino, Italy.
    Follo, Marie
    University of Freiburg, Germany.
    Chevalier, Jérôme
    Université de Lyon, France.
    Steinberg, Thorsten
    University of Freiburg, Germany.
    Kohal, Ralf Joachim
    University of Freiburg, Germany.
    Assessment of Novel Long-Lasting Ceria-Stabilized Zirconia-Based Ceramics with Different Surface Topographies as Implant Materials2017In: Advanced Functional Materials, ISSN 1616-301X, E-ISSN 1616-3028, Vol. 27, no 40, article id 1702512Article in journal (Refereed)
    Abstract [en]

    The development of long-lasting zirconia-based ceramics for implants, which are not prone to hydrothermal aging, is not satisfactorily solved. Therefore, this study is conceived as an overall evaluation screening of novel ceria-stabilized zirconia-alumina-aluminate composite ceramics (ZA8Sr8-Ce11) with different surface topographies for use in clinical applications. Ceria-stabilized zirconia is chosen as the matrix for the composite material, due to its lower susceptibility to aging than yttria-stabilized zirconia (3Y-TZP). This assessment is carried out on three preclinical investigation levels, indicating an overall biocompatibility of ceria-stabilized zirconia-based ceramics, both in vitro and in vivo. Long-term attachment and mineralized extracellular matrix (ECM) deposition of primary osteoblasts are the most distinct on porous ZA8Sr8-Ce11p surfaces, while ECM attachment on 3Y-TZP and ZA8Sr8-Ce11 with compact surface texture is poor. In this regard, the animal study confirms the porous ZA8Sr8-Ce11p to be the most favorable material, showing the highest bone-to-implant contact values and implant stability post implantation in comparison with control groups. Moreover, the microbiological evaluation reveals no favoritism of biofilm formation on the porous ZA8Sr8-Ce11p when compared to a smooth control surface. Hence, together with the in vitro in vivo assessment analogy, the promising clinical potential of this novel ZA8Sr8-Ce11 as an implant material is demonstrated. 

  • 450.
    Altmann, Brigitte
    et al.
    University Medical Center Freiburg, Germany.
    Rabel, Kerstin
    University Medical Center Freiburg, Germany.
    Kohal, Ralf J.
    University Medical Center Freiburg, Germany.
    Proksch, Susanne
    University Medical Center Freiburg, Germany.
    Tomakidi, Pascal
    University Medical Center Freiburg, Germany.
    Adolfsson, Erik
    RISE - Research Institutes of Sweden, Swerea, Swerea IVF.
    Bernsmann, Falk
    NTTF Coatings GmbH, Germany.
    Palmero, Paola
    Politecnico di Torino, Italy.
    Fürderer, Tobias
    MOESCHTER GROUP Holding GmbH, Germany.
    Steinberg, Thorsten
    University Medical Center Freiburg, Germany.
    Cellular transcriptional response to zirconia-based implant materials2017In: Dental Materials, ISSN 0109-5641, E-ISSN 1879-0097, Vol. 33, no 2, p. 241-255Article in journal (Refereed)
    Abstract [en]

    Objective To adequately address clinically important issues such as osseointegration and soft tissue integration, we screened for the direct biological cell response by culturing human osteoblasts and gingival fibroblasts on novel zirconia-based dental implant biomaterials and subjecting them to transcriptional analysis. Methods Biomaterials used for osteoblasts involved micro-roughened surfaces made of a new type of ceria-stabilized zirconia composite with two different topographies, zirconium dioxide, and yttria-stabilized zirconia (control). For fibroblasts smooth ceria- and yttria-stabilized zirconia surface were used. The expression of 90 issue-relevant genes was determined on mRNA transcription level by real-time PCR Array technology after growth periods of 1 and 7 days. Results Generally, modulation of gene transcription exhibited a dual dependence, first by time and second by the biomaterial, whereas biomaterial-triggered changes were predominantly caused by the biomaterials’ chemistry rather than surface topography. Per se, modulated genes assigned to regenerative tissue processes such as fracture healing and wound healing and in detail included colony stimulating factors (CSF2 and CSF3), growth factors, which regulate bone matrix properties (e.g. BMP3 and TGFB1), osteogenic BMPs (BMP2/4/6/7) and transcription factors (RUNX2 and SP7), matrix collagens and osteocalcin, laminins as well as integrin ß1 and MMP-2. Significance With respect to the biomaterials under study, the screening showed that a new zirconia-based composite stabilized with ceria may be promising to provide clinically desired periodontal tissue integration. Moreover, by detecting biomarkers modulated in a time- and/or biomaterial-dependent manner, we identified candidate genes for the targeted analysis of cell-implant bioresponse during biomaterial research and development.

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