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  • 1.
    Ai, Jiayi
    et al.
    China University of Petroleum, China; Macquarie University, Australia.
    Siljeström, Sandra
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Zhong, Ningning
    China University of Petroleum, China.
    Chen, Jianfa
    China University of Petroleum, China.
    Wang, Tieguan
    China University of Petroleum, China.
    Qiu, Nansheng
    China University of Petroleum, China.
    George, Simon
    Macquarie University, Australia.
    Co-existing two distinct formation mechanisms of micro-scale ooid-like manganese carbonates hosted in Cryogenian organic-rich black shales in South China2023Ingår i: Precambrian Research, ISSN 0301-9268, E-ISSN 1872-7433, Vol. 393, artikel-id 107091Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Manganese-rich deposits in the lower member of the Datangpo Formation (DTP) (ca. 663–654 Ma) in South China formed in the aftermath of the Cryogenian Sturtian glaciation. The Mn in the DTP occurs dominantly as rhodochrosite and Ca-rhodochrosite. A hydrothermal origin of the Mn2+ is shown by the rare earth element distribution and significantly high Mn/Fe ratios (3–19, average = 10.1). Previous studies suggested a microbially-mediated process for controlling the DTP black-shale hosted Mn carbonate deposits. However, detailed reports on the formation mechanisms of micro-scale (<2–5 μm) ooid-like Mn carbonates in the DTP have rarely been published. Systematic petrography and geochemical analyses in this study demonstrate the coexistence of two types of micro-scale ooidal-like Mn carbonates formed through two distinct mechanisms, either dominated by microbially-mediated or physiochemically-forced pathways. The Type I Mn carbonate has relatively larger grain size of 2–5 μm and exhibits a radial-concentric microfabric that shows signs of growth banding in the form of alternating light and dark laminae, which mainly express variation in Ca and Mn concentrations. The initial precipitation phase of the Type I Mn carbonate is interpreted to be Mn oxide/hydroxide, based on positive Ce anomalies and selective enrichments of particular trace elements. Novel evidence indicates that the capture of Mn as a carbonate phase directly from the water column by primarily precipitated calcite, which is referred to as the Type II Mn carbonate, has also contributed to the DTP Mn-rich deposits. Multiple roles of organic matter in Mn carbonate formation have been established: (1) catalysed Mn-redox cycling; (2) trapping and transportation of initial mineral precipitates to sediments; (3) serving as a carbon source; (4) regulating the morphology of the Mn carbonate. As a key link for understanding Cryogenian carbon and Mn cycling, specific formation pathways for the DTP Mn-carbonates are likely to have been controlled by given atmospheric-oceanic compositions (including oxygen level, pCO2, and redox conditions) in response to major geological and biological events during the interglacial period. In turn, massive storage of inorganic carbon and phosphorous in Mn carbonate phases would have had a substantial influence on biogeochemical carbon cycling during the Cryogenian. 

  • 2.
    Albæk, Julie Kamp
    et al.
    DTU Technical University of Denmark, Denmark.
    Shahbazi, Sasha
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    McAloone, Tim C.
    DTU Technical University of Denmark, Denmark.
    Pigosso, Daniela Cristina Antelmi
    DTU Technical University of Denmark, Denmark.
    Circularity evaluation of alternative concepts during early product design and development2020Ingår i: Sustainability, E-ISSN 2071-1050, Vol. 12, nr 22, artikel-id 9353Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Product design and development are essential for a circular transition. Circularity decisions, such as those concerning the type of material, assembly method, and expected lifespan, made during the early design stages will significantly influence a product’s quality, cost, esthetics, sustainability, and circularity performance over the product lifecycle. However, circularity is not often considered in the early stages of product design and development. This paper presents the development of the concept circularity evaluation tool (CCET), which aims to support the evaluation of alternative product concepts in terms of their circularity potential in the early stages of product design and development. The CCET was iteratively developed based on an extensive literature review of the success criteria for tool development, guidelines, and existing tools for circular product design and development and strong collaboration with manufacturing companies. The tool was tested and verified at four manufacturing companies in Nordic countries. The tool has been proven useful for evaluating the circularity of products and supportive in the decision-making process in the early stages of product design and development. © 2020 by the authors. Licensee MDPI, Basel, Switzerland.

  • 3.
    Almstrand, Ann-Charlotte
    et al.
    University of Gothenburg, Sweden.
    Bredberg, Anna
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Runstrom, Gunilla
    University of Gothenburg, Sweden.
    Karlsson, Helen
    Linköping University, Sweden.
    Assenhoj, Maria
    Linköping University, Sweden.
    Akdeve, Hatice Koca
    University of Gothenburg, Sweden.
    Olin, Anna-Carin
    University of Gothenburg, Sweden.
    Tinnerberg, Hakan
    University of Gothenburg, Sweden.
    Respiratory health among operators working in polymer additive manufacturing2023Ingår i: European Respiratory Journal, ISSN 0903-1936, E-ISSN 1399-3003, Vol. 62, nr 67, artikel-id PA3350Artikel i tidskrift (Refereegranskat)
  • 4.
    Almstrand, Ann-Charlotte
    et al.
    University of Gothenburg, Sweden; Sahlgrenska University Hospital, Sweden.
    Bredberg, Anna
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Runström Eden, Gunilla
    University of Gothenburg, Sweden; Sahlgrenska University Hospital, Sweden.
    Karlsson, Helen
    Linköping University, Sweden.
    Assenhöj, Maria
    Linköping University, Sweden.
    Koca, Hatice
    University of Gothenburg, Sweden; Sahlgrenska University Hospital, Sweden.
    Olin, Anna-Carin
    University of Gothenburg, Sweden; Sahlgrenska University Hospital, Sweden.
    Tinnerberg, Håkan
    University of Gothenburg, Sweden; Sahlgrenska University Hospital, Sweden.
    An explorative study on respiratory health among operators working in polymer additive manufacturing2023Ingår i: Frontiers In Public Health, ISSN 2296-2565, Vol. 11, artikel-id 1148974Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Additive manufacturing (AM), or 3D printing, is a growing industry involving a wide range of different techniques and materials. The potential toxicological effects of emissions produced in the process, involving both ultrafine particles and volatile organic compounds (VOCs), are unclear, and there are concerns regarding possible health implications among AM operators. The objective of this study was to screen the presence of respiratory health effects among people working with liquid, powdered, or filament plastic materials in AM. Methods: In total, 18 subjects working with different additive manufacturing techniques and production of filament with polymer feedstock and 20 controls participated in the study. Study subjects filled out a questionnaire and underwent blood and urine sampling, spirometry, impulse oscillometry (IOS), exhaled NO test (FeNO), and collection of particles in exhaled air (PEx), and the exposure was assessed. Analysis of exhaled particles included lung surfactant components such as surfactant protein A (SP-A) and phosphatidylcholines. SP-A and albumin were determined using ELISA. Using reversed-phase liquid chromatography and targeted mass spectrometry, the relative abundance of 15 species of phosphatidylcholine (PC) was determined in exhaled particles. The results were evaluated by univariate and multivariate statistical analyses (principal component analysis). Results: Exposure and emission measurements in AM settings revealed a large variation in particle and VOC concentrations as well as the composition of VOCs, depending on the AM technique and feedstock. Levels of FeNO, IOS, and spirometry parameters were within clinical reference values for all AM operators. There was a difference in the relative abundance of saturated, notably dipalmitoylphosphatidylcholine (PC16:0_16:0), and unsaturated lung surfactant lipids in exhaled particles between controls and AM operators. Conclusion: There were no statistically significant differences between AM operators and controls for the different health examinations, which may be due to the low number of participants. However, the observed difference in the PC lipid profile in exhaled particles indicates a possible impact of the exposure and could be used as possible early biomarkers of adverse effects in the airways. 

  • 5.
    Andersson, Anton
    et al.
    Luleå University of Technology, Sweden.
    Brander, Linus
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Lennartsson, Andreas
    Luleå University of Technology, Sweden.
    Roos, Åke
    Boliden AB, Sweden.
    Engström, Fredrik
    Luleå University of Technology, Sweden.
    A Method for Synthesizing Iron Silicate Slags to Evaluate Their Performance as Supplementary Cementitious Materials2023Ingår i: Applied Sciences, E-ISSN 2076-3417, Vol. 13, nr 14, artikel-id 8357Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Utilizing iron silicate copper slag as supplementary cementitious material (SCM) is a means to improve resource efficiency and lower the carbon dioxide emissions from cement production. Despite multiple studies on the performance of these slags in SCM applications, the variations in cooling procedure, grinding, and methods for evaluating reactivity limit the ability to assess the influence of chemical composition on reactivity from the literature data. In this study, a methodology was developed to synthesize iron silicate slags, which were then evaluated for their inherent reactivity using the R3 calorimeter-based experiments. The results demonstrated that laboratory-scale granulation produced the same reactivity as industrially granulated slag. Furthermore, a synthesized triplicate sample showed high repeatability. Based on these two aspects, this method can be used to systematically study the influence of chemical composition on the inherent reactivity of iron silicate slags while producing results that are directly translatable to industrial slags. © 2023 by the authors.

  • 6.
    Andersson, Anton
    et al.
    Luleå University of Technology, Sweden.
    Brander, Linus
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Lennartsson, Andreas
    Luleå University of Technology, Sweden.
    Roos, Åke
    Boliden AB, Sweden.
    Engström, Fredrik
    Luleå University of Technology, Sweden.
    Ground granulated iron silicate slag as supplementary cementitious material: Effect of prolonged grinding and granulation temperature2023Ingår i: Cleaner Materials, ISSN 2772-3976, Vol. 10, artikel-id 100209Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    The metallurgical and cement industries contribute significantly to anthropogenic carbon dioxide emissions. Utilizing oxidic by-products from the metallurgical industry as supplementary cementitious materials (SCMs) can improve resource efficiency and reduce emissions from cement production. Iron silicate copper slags have been studied as SCMs, but mainly in systems where Portland cement is used as an activator. There is limited research on the inherent reactivity of the slag under changing processing conditions. The present study offers insight into the effect of granulation temperature and grinding on the inherent reactivity of an industrially produced iron silicate copper slag. The results showed that granulation temperature had an insignificant effect on reactivity, while grinding generated substantial improvements. The latter effect was concluded to stem from the increased specific surface area, increased number of sites for nucleation and growth of hydrates, and changes in the inherent reactivity owing to structural changes induced by the grinding. 

  • 7.
    Andersson, Kristina
    et al.
    RISE Research Institutes of Sweden, Digitala system, Mobilitet och system.
    Hellström, Anna-Karin
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Lundahl, Jenny
    RISE Research Institutes of Sweden, Digitala system, Mobilitet och system.
    Challenges and opportunities with the EU Taxonomy Regulation– with focus on chemical safety and usage in complex products2023Rapport (Övrigt vetenskapligt)
    Abstract [en]

    The use of Policy Lab processes has been growing in Sweden and other countries to accelerate the adaptation of regulations to emerging technologies. Policy Lab facilitates active collaboration between relevant authorities, companies, and stakeholders through interactive and iterative methods based on Design Thinking principles. This approach bridges the gap between the legislative domain responsible for developing regulatory frameworks and the innovative companies that create solutions for emerging markets using new technologies and opportunities. In our study, we applied Policy Lab processes to the EU Taxonomy Regulation to identify challenges and opportunities related to chemical safety and usage for manufacturers of complex products. The EU Taxonomy Regulation, along with its delegated acts, represent a serious effort to establish standardized sustainability reporting within EU. However, it is still in its early stages and lacks maturity. Moreover, certain ambiguities within the regulation currently prevent a comprehensive comparison of companies due to the development of other legislations. Addressing these gaps depends on the future development of, for example, REACH. Our conclusion is that the EU Taxonomy Regulation is part of a larger “movement” that reflects the policymakers’ intentions. This intention also includes increased data sharing at a significantly different level compared to current practices. In the long run, the shift will enable authorities to access the data and develop new legislations. Our specific focus was on the objective of pollution prevention and control regarding the use and presence of hazardous substances listed in Appendix C of the EU Taxonomy Regulation. According to Appendix C, activities must not lead to the manufacture, placing on the market or use of listed substances, whether on their own, in mixture or in articles. Regarding listed substances, reference is made to existing EU legislation that regulates hazardous substances within the EU. The most challenging aspect in Appendix C is point (g), which aims to identify substances, whether alone, in mixtures, or in articles, that meet the criteria set out in Article 57 of REACH but are not yet included in the Candidate list. Our workshops, interviews, and literature review confirmed that the main challenge in meeting the criteria of Appendix C, specifically point (g) is the need to enhance transparency and traceability throughout supply chains. Overcoming these challenges requires addressing barriers, such as the lack of a harmonized regulatory framework across the value chain, the need for faster identification and restriction of hazardous substances, and the reinforcement of stronger enforcement measures. The enabling of full declaration of the hazardous properties and functions of the substances, while considering the balance between information disclosure and protecting trade secrets, would reduce the need for extensive tracking of substance of very high concern along the value chain. To improve communication along the value chain and identify data gaps while protecting trade secrets, workshop participants have proposed the use of a user-friendly interface based on traffic light scenario. This interface would serve as a filter mechanism, allowing product manufacturers to establish specific criteria for material suppliers to respond to. The objective is to enhance communication, establish criteria, and effectively identify data gaps. While the SCIP database ensures accessibility of information on articles containing substances from the Candidate List above 0.1 w/w%, it is limited to hazardous substances on that list. This means that hazardous substances not listed in the Candidate List may not be covered by the database. The EU Commission has proposed the implementation of a digital product passport to enhance information sharing about products and their supply chain, including substances of concern. Our study is conducted under the Mistra SafeChem program, where screening tools for hazard and exposure assessment of substances are currently being developed. These tools aim to provide screening data for direct decision-making based on the Defined Approach (DA). These screening tools have the potential to contribute to filling data gaps during the early design phases of complex products, particularly when screening for multiple material alternatives.

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  • 8.
    Andersson, Peter
    et al.
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning. University of Gothenburg, Sweden.
    Swanpalmer, J.
    University of Gothenburg, Sweden; Sahlgrenska University Hospital, Sweden.
    Palm, I.
    Sahlgrenska University Hospital, Sweden.
    Båth, M.
    University of Gothenburg, Sweden; Sahlgrenska University Hospital, Sweden.
    Chakarova, R.
    University of Gothenburg, Sweden; Sahlgrenska University Hospital, Sweden.
    Cylindrical ionization chamber response in static and dynamic 6 and 15 MV photon beams2023Ingår i: Biomedical Engineering & Physics Express, E-ISSN 2057-1976, Vol. 9, nr 2, artikel-id 025004Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Purpose. To investigate the response of the CC13 ionization chamber under non-reference photon beam conditions, focusing on penumbra and build-up regions of static fields and on dynamic intensity-modulated beams. Methods. Measurements were performed in 6 MV 100 × 100, 20 × 100, and 20 × 20 mm2 static fields. Monte Carlo calculations were performed for the static fields and for 6 and 15 MV dynamic beam sequences using a Varian multi-leaf collimator. The chamber was modelled using EGSnrc egs_chamber software. Conversion factors were calculated by relating the absorbed dose to air in the chamber air cavity to the absorbed dose to water. Correction and point-dose correction factors were calculated to quantify the conversion factor variations. Results. The correction factors for positions on the beam central axis and at the penumbra centre were 0.98-1.02 for all static fields and depths investigated. The largest corrections were obtained for chamber positions beyond penumbra centre in the off-axis direction. Point-dose correction factors were 0.54-0.71 at 100 mm depth and their magnitude increased with decreasing field size and measurement depth. Factors of 0.99-1.03 were obtained inside and near the integrated penumbra of the dynamic field at 100 mm depth, and of 0.92-0.94 beyond the integrated penumbra centre. The variations in the ionization chamber response across the integrated dynamic penumbra qualitatively followed the behaviour across penumbra of static fields. Conclusions. Without corrections, the CC13 chamber was of limited usefulness for profile measurements in 20-mm-wide fields. However, measurements in dynamic small irregular beam openings resembling the conditions of pre-treatment patient quality assurance were feasible. Uncorrected ionization chamber response could be applied for dose verification at 100 mm depth inside and close to large gradients of dynamically accumulating high- and low-dose regions assuming 3% tolerance between measured and calculated doses. © 2023 The Author(s).

  • 9.
    Andren, Oliver C. J.
    et al.
    KTH Royal Institute of Technology, Sweden.
    Ingverud, Tobias
    KTH Royal Institute of Technology, Sweden.
    Hult, Daniel
    KTH Royal Institute of Technology, Sweden.
    Håkansson, Joakim
    RISE - Research Institutes of Sweden (2017-2019), Biovetenskap och material, Kemi och material.
    Bogestål, Yalda
    RISE - Research Institutes of Sweden (2017-2019), Biovetenskap och material, Kemi och material.
    Caous, Josefin S
    RISE - Research Institutes of Sweden (2017-2019), Biovetenskap och material, Kemi och material. RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Blom, Kristina
    Medibiome AB, Sweden.
    Zhang, Yuning
    KTH Royal Institute of Technology, Sweden.
    Andersson, Therese
    RISE - Research Institutes of Sweden (2017-2019), Biovetenskap och material, Kemi och material.
    Pedersen, Emma
    RISE - Research Institutes of Sweden (2017-2019), Biovetenskap och material, Kemi och material.
    Björn, Camilla
    RISE - Research Institutes of Sweden (2017-2019), Biovetenskap och material, Kemi och material.
    Löwenhielm, Peter
    RISE - Research Institutes of Sweden (2017-2019), Biovetenskap och material, Kemi och material.
    Malkoch, Michael
    KTH Royal Institute of Technology, Sweden.
    Antibiotic-Free Cationic Dendritic Hydrogels as Surgical-Site-Infection-Inhibiting Coatings2019Ingår i: Advanced Healthcare Materials, ISSN 2192-2640, E-ISSN 2192-2659, artikel-id e1801619Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    A non-toxic hydrolytically fast-degradable antibacterial hydrogel is herein presented to preemptively treat surgical site infections during the first crucial 24 h period without relying on conventional antibiotics. The approach capitalizes on a two-component system that form antibacterial hydrogels within 1 min and consist of i) an amine functional linear-dendritic hybrid based on linear poly(ethylene glycol) and dendritic 2,2-bis(hydroxymethyl)propionic acid, and ii) a di-N-hydroxysuccinimide functional poly(ethylene glycol) cross-linker. Broad spectrum antibacterial effect is achieved by multivalent representation of catatonically charged β-alanine on the dendritic periphery of the linear dendritic component. The hydrogels can be applied readily in an in vivo setting using a two-component syringe delivery system and the mechanical properties can accurately be tuned in the range equivalent to fat tissue and cartilage (G' = 0.5-8 kPa). The antibacterial effect is demonstrated both in vitro toward a range of relevant bacterial strains and in an in vivo mouse model of surgical site infection.

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  • 10.
    Aramburu-Zabala, Marta
    et al.
    LORTEK-BRTA, Spain.
    Masurtschak, Simona
    LORTEK-BRTA, Spain.
    Moreno, Ramon
    LORTEK-BRTA, Spain.
    Jean-Jean, Jeremy
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Veiga, Angela
    CEIT-BRTA, Spain.
    Time Series Clustering for Knowledge Discovery on Metal Additive Manufacturing2020Ingår i: 21th International Conference on Intelligent Data Engineering and Automated Learning, IDEAL 2020, Springer Science and Business Media Deutschland GmbH , 2020, s. 447-455Konferensbidrag (Refereegranskat)
    Abstract [en]

    This work meets Metal Additive Manufacturing and Time Series Processing. It presents a four-step analytical procedure addressed to support the discovery of defect causes in 3D metal printing. The method has a phase of data space transformation, where the features space is firstly reduced and secondly exploited in a higher dimensional space. Later, a procedure for knowledge discovery is applied. Finally, by analyzing the results, it is concluded the most probable causes of the high rate of defects in the production phase. This procedure is proved with data obtained from a SLM machine, and the results are convincing.

  • 11.
    Aspegren, Anders
    et al.
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Bäckdahl, Henrik
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Storbritanniens satsning på tidig detektion av cancer med hjälp av flytande biopsier – beskrivning och analys2023Rapport (Övrigt vetenskapligt)
    Abstract [sv]

    Det pågår omfattande studier, framför allt i USA och Storbritannien, som undersöker möjligheterna att införa screening med hjälp av blodprover för tidig upptäckt av ett flertal cancerformer, så kallade MCED (Mulitple Cancer Early Detection). Ännu har inget faktiskt screeningsprogram med MCED-screening initierats i världen. I Sverige ställs idag höga krav på evidens från studier för att ett screeningprogram ska kunna införas. Det pågår studier som adresserar frågan om screening, men än så länge saknas mycket information. Med utgångspunkt i denna rapport kan därför inte en initiering av MCEDscreening i Sverige rekommenderas i dagsläget. För att vara i framkant bör Sverige dock följa området nogsamt. Grail är ett väletablerat företag som i augusti 2021 blev uppköpt av Illumina, ett företag som 2020 rapporterade en vinst på 2,34 miljarder USD. Företaget har stora ambitioner för framtida screeningprogram och kan bedömas ha de resurser som krävs att genomföra essentiella studier. De har säkrade medel och genomför projekt för att utveckla sin produkt för att fungera i en screeningsituation. Storbritanniens stora pågående studie ”NHS-Galleri Clinical Trial” beräknas publicera nya resultat under 2023. Om denna studie faller ut väl planeras en utvidgning av studien som ska omfatta en miljon personer. Denna större studie beräknas kunna avslutas 2030. Data att följa i nämnda ovanstående studie är bland annat: - Hur stor population ännu icke diagnostiserade utgör, i empiriska siffror - Utvecklingen av testmetoden gällande sensibilitet och sensitivitet - Patientnyttan, t.ex. ökar överlevnaden mot dagens siffror - Risken för överdiagnostik - Kostnader och logistik som kommer belasta sjukvården En problematik med MCED-screening är att testernas specificitet och sensitivitet behöver vara tillräckligt tillförlitliga för att det inte skall belasta snarare hjälpa samhället. Det är osannolikt att dessa värden kommer att vara 100-procentiga, men hur bra dessa värden bör vara innan man inför en screening är öppet för diskussion, däri ligger problematiken. I rapporten förklaras dessa begrepp i mer detalj. Det bör nämnas att Grail redan har kunnat presentera en ökad prestanda utifrån preliminära resultat ifrån pågående studier som presenterats i en så kallad sub-studie, där sensitivitet, sensibilitet och ”Tissue of Origin” (TOO) har förbättrats ytterligare gällande tolv olika cancerformer. Beräkningar i vår rapport har nyttjat dessa värden för att söka ge en bild över vad som kan förväntas vid ett införande av en Grail-MCED-screening i Sverige. För de tolv cancerformerna kan beräkningarna sammanfattas enligt; - Under förutsättning att det finns adekvat behandling att erbjuda vid tidigare diagnostik, kommer det ske en markant förskjutning av i vilket stadie som diagnostiserade individer detekteras och förhoppningsvis behandlas. Idag behandlas cirka 40 -45% av de cancerdiagnostiserade i stadie III/IV, att jämföras mot de beräknade 6% vid införande av årlig screening. - Ökningen av antalet individer som skulle överleva sin cancer uppskattas till mellan 3 - 5 000 individer, utöver de cirka 9 000 som överlever med hjälp av dagens diagnostik/behandling. - 25 – 35% kostnadsreducering både vad gäller direkta kostnader och samhällskostnader, extrapolerat från IHE rapport (1). Vi har dock inte tagit hänsyn till de kostnadsökningar ett införande av en MCED-screening skulle innebära. Det reella värdet av rapportens beräkningar bör vägas mot de empiriska data som kommer produceras av NHS studie av Grails metod. Starka avvikelser (”positiva/negativa”) från empiriska data kan då ligga till grund för om och i så fall hur pass snabbt man vill driva införande av MCED screening i Sverige. Rapportens sammantagna bedömning är att de av Socialstyrelsen uppsatta kriterier för införande av en screening, inte är uppfyllda i dagsläget. Men vi har även försökt visualisera vad som skulle komma att ske med dagens diagnostiserade cancerpatientgrupper om en MCED-screening införs i ålderspopulationen 40 – 80 år (96% av dagens diagnostiserade), på de tolv cancerformer som metoden visar bäst sensibilitet/sensitivitet mot. Dessa tolv cancerformer utgör 36% av dagens diagnostiserade patienter. Trots att ett införande av screening inte är att rekommendera i dagsläget, finns det alternativ att ta ställning till; - Endast avvakta utredningarna i Storbritannien (till 2023, eller till 2030). - Avvakta utredningarna men initiera samtal med beslutsfattare som styr över de ekonomiska medel som kan bistå med satsningar på större Grailtester i Sverige - Avvakta utredningarna, men initiera samtal med både NHS och Grail i syfte att behålla momentum i detta första initiativ till utredning. Författarnas uppfattning är att Grails teknik är signifikant och kommer med stor sannolikhet bedömas som tillämpbar för MCED-screening i framtiden.

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  • 12.
    Bengtsson, Emanuel
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Livscykelanalys av stenskottsåtgärder2024Rapport (Övrigt vetenskapligt)
    Abstract [sv]

    Syftet med denna studie var att utvärdera miljöpåverkan från åtgärder som stenskottsskador på vindrutor kan ge upphov till i form av byte respektive reparation av en ruta. Studien omfattade hela livscykeln från vagga till grav med fokus på klimatpåverkan, men inkluderade även fler miljöpåverkanskategorier. Den funktionella enheten definierades som att åtgärda en vindruta på 15 kg med stenskottsskada genom antingen reparation eller byte av rutan. För reparation inkluderades transport av fordon till och från verkstad samt energi- och materialåtgång under själva reparationen i verkstaden. Byte omfattade i sin tur transport av fordon till och från verkstad, tillverkning av ny ruta, transport av ny ruta till verkstad, energi- och materialåtgång vid själva bytet, samt avfallshantering av den utbytta rutan. Resultaten från denna livscykelanalys visade på tydliga miljömässiga fördelar med att reparera jämfört med att byta en stenskottsskadad vindruta. Baserat på de grundantaganden som gjordes beräknades ett byte ge upphov till en klimatpåverkan på omkring 88 kg CO2-ekv och en reparation omkring 18 kg CO2-ekv. Det innebär en besparing på cirka 70 kg CO2-ekv och att en ruta kan repareras fyra gånger innan klimatpåverkan överstiger den vid ett byte. Majoriteten av påverkan vid ett byte tillskrevs tillverkningen av rutan (ca 56%), följt av transporten av fordonet till och från verkstaden (ca 20%), samt transporten av rutan till verkstaden (ca 14%). Avfallshanteringen och själva bytet på verkstaden hade båda liten påverkan. För en reparation orsakades nästan hela påverkan av transporten av fordonet till och från verkstaden (ca 97%), medan själva reparationsprocessen gav försumbart bidrag. Om flera reparationer genomförs för att undvika ett byte är det därför främst transporten av fordonet till och från verkstaden som är viktig att beakta och minimera för att undvika att reparation ger högre påverkan än byte. En liknande trend som för klimatpåverkan observerades även för miljöpåverkanskategorierna försurning, marin övergödning, terrester övergödning, fotokemisk ozonbildning, fossil resursanvändning och vattenanvändning, där en reparation motsvarade 19-30% av påverkan från ett byte. Övriga studerade kategorier i form av sötvattenövergödning, ozonförtunning och resursanvändning av metaller och mineral visade en mindre skillnad, där en reparation motsvarade 45-52% av påverkan från ett byte. Den mindre skillnaden orsakades av transporten till och från verkstaden, som antogs vara samma oavsett åtgärd. Sammanfattningsvis pekade dessa resultat på att åtgärder mot att reducera klimatpåverkan också verkar ge positiva effekter på andra miljöaspekter. Känslighetsanalyserna som genomfördes identifierade transporten av fordonet till och från verkstaden som en viktig faktor att beakta. Distansen hade stor betydelse för den totala påverkan, men även fordonstyp och drivlina. Transporten av en ny ruta till verkstaden identifierades också som en viktig parameter att ta hänsyn till. Denna transport påverkades i sin tur av vikten på rutan, ytterligare en parameter med signifikant påverkan på resultatet vid byte av ruta. Vidare visade känslighetsanalyserna att så länge en energimix med relativt låg klimatpåverkan används, som exempelvis en svensk, har både själva bytes- och reparationsprocessen liten påverkan. Beträffande avfallshanteringen identifierades viss potential i att återvinna glaset genom den systemexpansion som genomfördes, något som motiverar fortsatt strävan mot återvinning av vindrutor. I övrigt syntes inga stora skillnader i resultat beroende på hur den utbytta rutan avfallshanteras, givet den cut-off-metodik som studien byggde på.

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  • 13.
    Benison, K. C.
    et al.
    West Virginia University, USA.
    Siljeström, Sandra
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Yanchilina, A.
    California Institute of Technology, USA.
    Depositional and Diagenetic Sulfates of Hogwallow Flats and Yori Pass, Jezero Crater: Evaluating Preservation Potential of Environmental Indicators and Possible Biosignatures From Past Martian Surface Waters and Groundwaters2024Ingår i: Journal of Geophysical Research - Planets, ISSN 2169-9097, E-ISSN 2169-9100, Vol. 129, nr 2, artikel-id e2023JE008155Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    The Mars 2020 Perseverance rover has examined and sampled sulfate-rich clastic rocks from the Hogwallow Flats member at Hawksbill Gap and the Yori Pass member at Cape Nukshak. Both strata are located on the Jezero crater western fan front, are lithologically and stratigraphically similar, and have been assigned to the Shenandoah formation. In situ analyses demonstrate that these are fine-grained sandstones composed of phyllosilicates, hematite, Ca-sulfates, Fe-Mg-sulfates, ferric sulfates, and possibly chloride salts. Sulfate minerals are found both as depositional grains and diagenetic features, including intergranular cement and vein- and vug-cements. Here, we describe the possibility of various sulfate phases to preserve potential biosignatures and the record of paleoenvironmental conditions in fluid and solid inclusions, based on findings from analog sulfate-rich rocks on Earth. The samples collected from these outcrops, Hazeltop and Bearwallow from Hogwallow Flats, and Kukaklek from Yori Pass, should be examined for such potential biosignatures and environmental indicators upon return to Earth. 

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  • 14.
    Berglin, Mattias
    et al.
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning. University of Gothenburg, Sweden.
    Cavanagh, Jorunn Pauline
    Amicoat A/S, Norway; UiT The Arctic University of Norway, Norway.
    Caous, Josefin Seth
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Thakkar, Balmukund Sureshkumar
    Amicoat A/S, Norway.
    Vasquez, Jeddah Marie
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Stensen, Wenche
    UiT The Arctic University of Norway, Norway.
    Lyvén, Benny
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Svendsen, John-Sigurd
    Amicoat A/S, Norway; UiT The Arctic University of Norway, Norway.
    Svenson, Johan
    RISE Research Institutes of Sweden, Material och produktion.
    Flexible and Biocompatible Antifouling Polyurethane Surfaces Incorporating Tethered Antimicrobial Peptides through Click Reactions2024Ingår i: Macromolecular Bioscience, ISSN 1616-5187, E-ISSN 1616-5195, Vol. 4, artikel-id 2300425Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Efficient, simple antibacterial materials to combat implant-associated infections are much in demand. Herein, the development of polyurethanes, both cross-linked thermoset and flexible and versatile thermoplastic, suitable for “click on demand” attachment of antibacterial compounds enabled via incorporation of an alkyne-containing diol monomer in the polymer backbone, is described. By employing different polyolic polytetrahydrofurans, isocyanates, and chain extenders, a robust and flexible material comparable to commercial thermoplastic polyurethane is prepared. A series of short synthetic antimicrobial peptides are designed, synthesized, and covalently attached in a single coupling step to generate a homogenous coating. The lead material is shown to be biocompatible and does not display any toxicity against either mouse fibroblasts or reconstructed human epidermis according to ISO and OECD guidelines. The repelling performance of the peptide-coated materials is illustrated against colonization and biofilm formation by Staphylococcus aureus and Staphylococcus epidermidis on coated plastic films and finally, on coated commercial central venous catheters employing LIVE/DEAD staining, confocal laser scanning microscopy, and bacterial counts. This study presents the successful development of a versatile and scalable polyurethane with the potential for use in the medical field to reduce the impact of bacterial biofilms. 

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  • 15.
    Berglund, Martina
    et al.
    Linköping University, Sweden.
    Harlin, Ulrika
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Elg, Mattias
    Wallo, Andreas
    Linköping University, Sweden.
    Scaling up and scaling down: Improvisational handling of critical work practices during the COVID-19 pandemic2024Ingår i: Management Learning, ISSN 1350-5076, E-ISSN 1461-7307, Vol. 55, s. 305-Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    The aim of this article is to explore improvisational handling of critical work practices during the COVID-19 pandemic and interpret these practices from a learning perspective. Based on an interview study with representatives of private, public and intermediary organisations, the study identified three different types of improvisational handling as responses to the pandemic crisis involving ‘scaling up’ and ‘scaling down’ critical work practices. By ‘scaling up’ and ‘scaling down’, we refer to practices for which, due to the pandemic, it has been imperative to urgently scale up an existing operational process or develop a new process, and alternatively extensively scale down or cease an existing process. The types of improvisational handling differed depending on the discretion of involved actors in terms of the extent to which the tasks, methods and/or results were given beforehand. These types of improvisational handling resulted in temporary solutions that may become permanent after the pandemic. The framework and model proposed in the article can be used as a tool to analyse and learn from the changes in work practices that have been set in motion during the pandemic. Such learning may improve the ability to cope with future extensive crises and other rapid change situations. © The Author(s) 2022.

  • 16.
    Berglund, Martina
    et al.
    Linköping University, Sweden.
    Harlin, Ulrika
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Säfsten, Kristina
    Jönköping University, Sweden.
    Interactive research in production start-up—application and outcomes2020Ingår i: Journal of Manufacturing Technology Management, ISSN 1741-038X, E-ISSN 1758-7786, Vol. 31, nr 8, s. 1561-1581Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Purpose: The purpose of this paper is to reflect on interactive research as a means to create relevant knowledge in the domain of operations management in general and specifically in the context of production start-up. Design/methodology/approach: The reflection on the use of interactive research in production start-ups was based on a study of two completed interactive research projects. The lens for reflection was a framework including context, quality of relationship, quality of the research process itself and outcomes. Findings: The context was industrial manufacturing companies in Sweden, with different kind of challenges related to production start-ups, such as collaboration between involved functions and suppliers, competence development and work routines. Indicators of the quality of relationship between researchers and practitioners were initiated development activities and new collaboration between functions, within the company, between companies and in supply chains. The reflection of the quality of the research process itself was based on an interactive research process including four iterative steps with regular follow-ups allowing joint practitioner and researcher reflection on the progress. Identified outcomes included increased awareness and competence on how to deal with production start-ups, improvements of communication, work procedures and structures, better use of competences, increased cross-functional dialogue and cultural understanding. Practical implications: Implications for practitioners are the possibilities for knowledge creation through interactive collaboration in research projects enabling exchange between researchers from complementary fields and other companies dealing with production start-ups. Originality/value: The interactive research approach enables joint knowledge creation in a fast-changing context such as production start-ups as well as value-adding results both for practitioners in industry and for academia. 

  • 17.
    Birkie, Seyoum Eshetu
    et al.
    KTH Royal Institute of Technology, Sweden.
    Chavez, Zuhara Zemke
    KTH Royal Institute of Technology, Sweden.
    Lindahl, Emma
    KTH Royal Institute of Technology, Sweden.
    Kurdve, Martin
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Bruch, Jessica
    Mälardalen University, Sweden.
    Bellgran, Monica
    KTH Royal Institute of Technology, Sweden.
    Bohlin, Lotta
    KTH Royal Institute of Technology, Sweden.
    Bohman, Mikael
    AstraZeneca, Sweden.
    Elvin, Malin
    Mälardalen University, Sweden.
    Systematic Green Design in Production Equipment Investments: Conceptual Development and Outlook2023Ingår i: IFIP Advances in Information and Communication Technology, ISSN 1868-4238, Vol. 692 AICT, s. 174-188Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    This paper explores the concept of green design in the context of production, focusing on investment projects for production equipment design and acquisition by a manufacturing firm. Research towards making manufacturing and production related activities more sustainable is increasing. In the manufacturing sector, environmental sustainability tends to be more commonly approached from the operations perspective. However, the decisions taken in the design phase of the production equipment significantly impact the operations phase. Therefore, proactive design approaches for sustainability applied in product design settings could be transferred to the design of the production equipment to build in green aspects from the outset. This study explores the research questions of what green production equipment design entails and how the concept of green design has evolved in the context of production. Overall, this conceptual paper highlights the importance of incorporating green design principles from the outset of the production design. Transferable methodological issues are also explored for further detailed investigation in the production equipment design context. Strong collaboration between equipment suppliers and the buying manufacturer that aims to integrate sustainability as part of requirements is proposed as an enabler for the way forward. The paper also provides insights into the evolution of the concept in this context for possible future research.

  • 18.
    Blomsma, Fenna
    et al.
    DTU Technical University of Denmark, Denmark.
    Pieroni, Marina
    DTU Technical University of Denmark, Denmark.
    Kravchenko, Mariia
    DTU Technical University of Denmark, Denmark.
    Pigosso, Daniela
    DTU Technical University of Denmark, Denmark.
    Hildenbrand, Jutta
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Kristinsdottir, Anna Runa
    RISE - Research Institutes of Sweden (2017-2019), Material och produktion, IVF.
    Kristoffersen, Eivind
    NTNU Norwegian University of Science and Technology, Norway.
    Shabazi, Sasha
    RISE - Research Institutes of Sweden (2017-2019), Material och produktion, IVF.
    Nielsen, Kjartan
    Innovation Center Iceland, Iceland.
    Jönbrink, Anna Karin
    RISE - Research Institutes of Sweden (2017-2019), Material och produktion, IVF.
    Li, Jingyue
    NTNU Norwegian University of Science and Technology, Norway.
    Wiik, Carina
    Technology Industries of Finland, Finland.
    McAloone, Yim
    DTU Technical University of Denmark, Denmark.
    Developing a circular strategies framework for manufacturing companies to support circular economy-oriented innovation2019Ingår i: Journal of Cleaner Production, ISSN 0959-6526, E-ISSN 1879-1786, Vol. 241, artikel-id 118271Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    This paper puts forward the Circular Strategies Scanner: a framework that introduces a taxonomy of circular strategies developed for use by manufacturing companies engaging in circular economy (CE) oriented innovation. Currently, a range of frameworks exists that propose a vision for how to operate in a CE, by identifying and organising relevant circular strategies. However, these frameworks have a limited applicability for specific business types, in particular manufacturing, and are unsuitable for use in CE oriented innovation, due to a lacking ability to support innovation processes through: 1) creating a comprehensive understanding of circular strategies, 2) mapping strategies currently applied and 3) finding opportunities for improved circularity across a range of business processes. This paper addresses these shortcomings by proposing a circular strategies framework for the manufacturing context, titled the Circular Strategies Scanner, which provides a comprehensive set of definitions of circular strategies and directly supports the early stages of CE oriented innovation. With this, the paper contributes to the body of work that develops CE transition methodology.

  • 19.
    Boge, Lukas
    et al.
    RISE - Research Institutes of Sweden (2017-2019), Biovetenskap och material, Yta, process och formulering. Chalmers University of Technology, Sweden.
    Browning, Kathryn
    University of Copenhagen, Denmark.
    Nordström, Randi
    Uppsala University, Sweden.
    Campana, Mario
    Rutherford Appleton Laboratory, UK.
    Damgaard, Liv
    University of Copenhagen, Denmark.
    Seth Caous, Josefin
    RISE - Research Institutes of Sweden (2017-2019), Biovetenskap och material, Kemi och material. RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Hellsing, Maja
    RISE - Research Institutes of Sweden (2017-2019), Biovetenskap och material, Yta, process och formulering.
    Ringstad, Lovisa
    RISE - Research Institutes of Sweden (2017-2019), Biovetenskap och material, Kemi och material.
    Andersson, Martin
    Chalmers University of Technology, Sweden.
    Peptide-Loaded Cubosomes Functioning as an Antimicrobial Unit against Escherichia coli2019Ingår i: ACS Applied Materials and Interfaces, ISSN 1944-8244, E-ISSN 1944-8252, Vol. 11, nr 24, s. 21314-21322Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Dispersions of cubic liquid crystalline phases, also known as cubosomes, have shown great promise as delivery vehicles for a wide range of medicines. Due to their ordered structure, comprising alternating hydrophilic and hydrophobic domains, cubosomes possess unique delivery properties and compatibility with both water-soluble and -insoluble drugs. However, the drug delivery mechanism and cubosome interaction with human cells and bacteria are still poorly understood. Herein, we reveal how cubosomes loaded with the human cathelicidin antimicrobial peptide LL-37, a system with high bacteria-killing effect, interact with the bacterial membrane and provide new insights into the eradication mechanism. Combining the advanced experimental techniques neutron reflectivity and quartz crystal microbalance with dissipation monitoring, a mechanistic drug delivery model for LL-37-loaded cubosomes on bacterial mimicking bilayers was constructed. Moreover, the cubosome interaction with Escherichia coli was directly visualized using super-resolution laser scanning microscopy and cryogenic electron tomography. We could conclude that cubosomes loaded with LL-37 adsorbed and distorted bacterial membranes, providing evidence that the peptide-loaded cubosomes function as an antimicrobial unit.

  • 20.
    Boss, Annika
    et al.
    RISE Research Institutes of Sweden, Material och produktion, Polymera material och kompositer.
    Strid, Anna
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Olsson, Elisabeth
    RISE Research Institutes of Sweden.
    Andersson, Emelie
    RISE Research Institutes of Sweden, Material och produktion, Polymera material och kompositer.
    Brodin, Malin
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Andersson, Mattias
    RISE Research Institutes of Sweden, Material och produktion, Polymera material och kompositer.
    Ämnen som hindrar eller försvårar återvinning av plast i prioriterade produktgrupper inom byggsektorn2023Rapport (Övrigt vetenskapligt)
    Abstract [sv]

    I detta uppdrag undersöker vi kemiska tillsatser i plaster som försvårar eller utgör hinder för återvinning av materialet. I denna rapport avser kemiska tillsatser additiv som medvetet introducerats i produkten eller materialet, och det är dessa kemiska ämnens natur som avgör problematiken ur återvinningssynpunkt. Vi fokuserar på byggsektorn eftersom denna sektor använder stora mängder plast av hög kvalité. Trots detta är återvinningsgraden för plast låg och potentialen att öka återvinningsgraden är därmed stor. Ett materials potential för återvinning bestäms av flera faktorer, varav kemikalieinnehåll är en. Det är viktigt att tänka på vilken eller vilka produkter plasten är lämplig att återvinnas till, och hänsyn måste alltid tas till gällande kemikalielagstiftning för just de produkttyperna. Kemiska ämnen som kan vara skadliga för människan och/eller miljön är särskilt viktiga att utreda, men det finns också andra tillsatser i material och produkter som försvårar återvinningsprocessen eller påverkar kvalitén på den återvunna plasten negativt så att marknaden för det återvunna materialet blir begränsad. Ytterligare en faktor att ta i beaktande är hur exponeringen för kemikalierna ser ut, om de är bundna i plasten eller kan emitteras och utsätta människor och miljön för direkta risker. De stora kategorierna i denna kartläggning har varit golv, rör och rördelar, kablar, profiler och lister, isoleringsmaterial, samt tätningsskikt. För dessa produktgrupper dominerar polymertyperna PVC, PE av olika densitetsgrad och comonomer-innehåll, PP (homo- och copolymer), PS och PUR. Då härdplaster, där även PUR ingår, förekommer i form av lacker, adhesiv och ytbeläggningar i byggprodukter behandlas dessa också övergripande. Många materialströmmar finns tillgängliga för återvinning inom kategorin byggplast generellt sett, men möjligheterna och incitamenten att sortera ut dessa i sina ursprungliga fraktioner är låg. Detta beror antingen på att efterfrågan på mekaniskt återvunnet material i dessa produktkategorier inte är stor nog, som för PEX och vissa typer av rör, eller på att volymerna är för låga för lönsamhet. Ett exempel på det sistnämnda är profiler och lister av PVC där etablerad cirkulär återvinning finns ute i Europa, men produktkategorin är för liten i Sverige för att drivkraften ska uppstå. Eftersom flera av de polymermaterial och produkter vi kartlagt i denna rapport har en historisk användning av idag reglerade, eller till och med förbjudna kemiska ämnen, kompliceras återvinningen av byggplast i att de inkommande avfallsströmmarna är av mycket varierande ålder. För att möjliggöra en högre återvinningsgrad och bättre kvalitet krävs därför utökad och mer noggrann sortering så att problematiska, och i vissa fall hälso- och miljöfarliga, innehållsämnen inte följer med i den mekaniska återvinningen, men inte heller så att kvalitativa fraktioner av en viss produkt- och polymertyp avvisas från återvinning av säkerhetsskäl. Ett axplock av problematiska tillsatser är tungmetallstabilisatorer och mjukgörare i produkter av PVC, flamskyddsmedel i isolering av EPS och XPS, samt silanförnätad PEX som innehåller tennkatalysator. Kontaminering i form av härdplastrester, felsorterad PEX i PE-recyklat, samt tejper och fogar på tätskikt utgör de mer oavsiktliga, fysiska hindren för kvalitetsmässig återvinning tillsammans med faktumet att en stor del av kablar och rör helt enkelt inte utvinns ur marken efter sin användningstid. Sammanfattningsvis skulle fler fraktioner av byggplast kunna återvinnas mekaniskt genom att stärka infrastrukturen kring insamling och sortering, men för detta krävs ökad efterfrågan och långsiktig lönsamhet. Kemiska återvinningsmetoder seglar upp som en möjlig lösning för flera av de hinder som identifieras i denna studie, till exempel tvärbundna material, material med hög andel fyllmedel, eller för avskiljning av oönskade tillsatser likt tungmetaller och ftalater. Kartläggningen av detta område får därför ses som en intressant frågeställning för ytterligare arbete.

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  • 21.
    Brunklaus, Birgit
    et al.
    RISE Research Institutes of Sweden, Samhällsbyggnad, Systemomställning och tjänsteinnovation.
    Chiew, Yoon Lin
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Dincer, Hasan
    Telge Återvinning, Sweden.
    Nilsson-Lindén, Hanna
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Saarikko, Ted
    Umeå University, Sweden.
    Sten, Ulrika
    Södertälje kommun, Sweden.
    Sundberg, Andreas
    Södertälje kommun, Sweden.
    Det inkluderande, hållbara och uppkopplade samhället : Utvärdering och framtidsanalys2023Rapport (Övrigt vetenskapligt)
    Abstract [sv]

    Södertälje kommun har höga ambitioner att drastiskt sänka sin klimatpåverkan och har ambitionen att inte ha några nettoutsläpp av växthusgaser år 2030 (Södertälje kommun Miljö- och klimatstrategi 2022–2030, 2022). För att nå dessa mål spelar avfallssektorn i Södertälje kommun en avgörande roll, vilket också innebär ett behov av större involvering och ett större engagemang från medborgare och företag. Som en del i det arbetet skapades projektet Det inkluderande, hållbara och uppkopplade samhället. Projektet är ett samarbete mellan Södertälje kommun, Telge Återvinning, RISE Research Institutes of Sweden och Umeå Universitet och avser att undersöka hur maskingenererad data kan ha dubbel nytta i att både skapa externt medborgarvärde och internt organisatoriskt värde i Södertälje kommuns omställning till en hållbar stad. Denna rapport inkluderar en nulägesanalys över tre tematiserade områden; digitalisering, livscykelanalys (LCA), och medborgardialog. Södertälje kommun har tillsammans med Telge Nät byggt upp ett så kallat LoRaWAN2 (ett trådlöst nätverk med dubbelriktad kommunikation3) i Södertälje för att underlätta kommunikation mellan sensorer i uppkopplade enheter. 169 papperskorgar har också försetts med sensorer som mäter fyllnadsgrad, vilket genererat ett proof-of-concept för hur uppkopplad utrustning kan möjliggöra ruttoptimering och placeringsplanering. Att koppla upp en papperskorg har i det här fallet inneburit att man fäster en sensor i locket på befintliga kärl. Denna sensor känner sedan av fyllnadsgraden i papperskorgens plastpåse med jämna mellanrum. Initiativet kring uppkopplade papperskorgar har medfört inlärning på flera nivåer – såväl utvecklarna som utformar sensorerna, som medarbetarna som förlitar sig på dem, har behövt tänka i nya banor och ompröva invanda arbetssätt. Värt att notera är att personalen behöver besöka samtliga områden där papperskorgar finns trots sensortekniken i och med att deras arbetsuppgifter även inkluderar renhållning av gator och vård av grönytor. Det vill säga, det föreligger i nuläget inte en kvantitativ ekonomisk vinst utan snarare en kvalitativ nytta i form av ökade möjligheter att planera sin arbetstid vilket kan leda till en renare stad. Bland de system som Södertälje kommun använder ses två som särskilt intressanta i relation till Sakernas Internet (Internet of Things (IoT)) enligt denna nulägesanalys. På en operativ nivå har Infracontrol potential att anta rollen som ”spindeln i nätet” där status på uppkopplad utrustning kan hanteras. På en strategisk nivå erbjuder verktyget Maptionnaire möjligheter att aggregera, analysera, och presentera data från uppkopplad utrustning. För att realisera potentialen hos dessa (och andra) verktyg krävs dock att Södertälje kommun ställer nya krav och utarbetar nya rutiner vid upphandling då kostnaderna för att integrera uppkopplad utrustning annars skulle bli ohållbar. En LCA har genomförts för att utvärdera miljöpåverkan från sakernas Internet i Södertälje centrum för smart sophämtning ur ett livscykelperspektiv. Med koppling till kommunens klimatstrategi har miljöpåverkan med fokus på klimatpåverkan prioriterats. Den visar att IoT-systemet enbart utgör en liten del av klimatpåverkan (122 kg CO2-ekv per år4), vilket främst härrör från gateways (50%) och sensorer (27%) och användning av Internet (23%). Sophämtningen bidrar med cirka 12 ton CO2-ekv per år, vilket främst bidrog till användningen av fossilbaserade avfallspåsar i plast (96%) och Hydrerad Vegetabilisk Olja (HVO)-baserade transporter (4%). Vidare visar LCAn att potential för framtida klimatsmart sophämtningssystemet ligger inom minskad användning av fossila plastpåsar och smart planering av sophämtning för att reducera transporter. Södertälje har redan minskat sin klimatpåverkan från transporter (under 2016) genom byte från diesel till HVO. För ett system med 169 papperskorgar (studiens utgångspunkt) innebar detta 83% minskning, från 2,3 ton till 380 kg. Enbart två ton av denna minskning härrör från fossilfria transporter (resp. 8,75 ton för ett möjligt framtida system med 700 papperskorgar). Dock visar resultaten att ännu mer klimatpåverkan kan minskas genom att inte använda fossila plastpåsar, nästan 12 ton (resp. 50 ton för 700 papperskorgar). Detta motsvarar fem resor till Thailand (2,5 ton per resa) eller utsläpp för fyra invånare (2,8 ton per invånare) för året 2030. För ett system med 700 papperskorgar betyder det minst 20 resor till Thailand eller utsläpp för upp till 20 invånare per år. Vidare har projektet ett fokus på inkludering av medborgare i frågor kring hållbarhet, med syftet att informera, engagera och inkludera medborgare i målet med att uppnå hållbar resurshantering. Medborgardialog kan ske på många olika vis och innebära olika saker. Nulägesanalysen visar att flera olika aktiviteter genomförts på området, och att dessa framförallt kan kopplas till kategorierna ”information” och ”konsultation”, men där också det finns kommande inslag av ”dialog” med till exempel det Hackathon som planeras. Från nulägesanalysen noterades dock en möjlighet till utökat fokus på medborgardialog i Södertälje, samt att det finns en medvetenhet om behovet av att inkludera många olika grupper i denna dialog, men det noterades även en utmaning vad gäller inkludering och olika språk.

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  • 22.
    Brunklaus, Birgit
    et al.
    RISE Research Institutes of Sweden, Samhällsbyggnad, Systemomställning och tjänsteinnovation.
    Chiew, Yoon Lin
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Lundström, Anders
    Umeå University, Sweden.
    Mccarrick, Anthony
    Södertälje kommun, Sweden.
    Nilsson-Lindén, Hanna
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Rekonius, Robert
    Telge Återvinning, Sweden.
    Saarikko, Ted
    Umeå University, Sweden.
    Sundberg, Andreas
    Södertälje kommun, Sweden.
    Thernström, Thomas
    Södertälje kommun, Sweden.
    Det inkluderande, hållbara och uppkopplade samhället: Nulägesanalys2021Rapport (Övrigt vetenskapligt)
    Abstract [sv]

    Södertälje kommun har höga ambitioner att drastiskt sänka sin klimatpåverkan och har målet att inte ha några nettoutsläpp av växthusgaser år 2030. För att nå dessa mål spelar avfallssektorn i Södertälje kommun en avgörande roll, vilket också innebär ett behov av större involvering och ett större engagemang från medborgare och företag. Som en del i det arbetet skapades projektet Det inkluderande, hållbara och uppkopplade samhället. Projektet är ett samarbete mellan Södertälje kommun, Telge Återvinning, RISE Research Institutes of Sweden och Umeå Universitet och avser att undersöka hur IoT-genererad data kan ha dubbel nytta i att både skapa externt medborgarvärde och internt organisatoriskt värde i Södertälje kommuns omställning till en hållbar stad. Denna rapport inkluderar en nulägesanalys över tre tematiserade områden; digitalisering, livscykelanalys (LCA), och medborgardialog. Södertälje kommun har tillsammans med Telge Nät byggt upp ett så kallat LoRaWAN (ett trådlöst nätverk med dubbelriktad kommunikation) i Södertälje för att underlätta kommunikation mellan sensorer i uppkopplade enheter. 169 papperskorgar har också försetts med sensorer som mäter fyllnadsgrad, vilket genererat ett proof-of-concept för hur uppkopplad utrustning kan möjliggöra ruttoptimering och placeringsplanering. Att koppla upp en papperskorg innebär i praktiken att man fäster en sensor i locket på befintliga kärl. Denna sensor känner sedan av fyllnadsgraden i papperskorgens plastpåse med jämna mellanrum. Initiativet kring uppkopplade papperskorgar har medfört inlärning på flera nivåer – såväl utvecklarna som utformar sensorerna, som medarbetarna som förlitar sig på dem, har behövt tänka i nya banor och ompröva invanda arbetssätt. Värt att notera är att personalen behöver besöka samtliga områden där papperskorgar finns trots sensortekniken i och med att deras arbetsuppgifter även inkluderar renhållning av gator och vård av grönytor. Det vill säga, det föreligger i nuläget inte en kvantitativ ekonomisk vinst utan snarare en kvalitativ nytta i form av en potentiellt renare stad. Bland de system som Södertälje kommun använder ses två som särskilt intressanta i relation till Sakernas Internet enligt denna nulägesanalys. På en operativ nivå har Infracontrol potential att anta rollen som ”spindeln i nätet” där status på uppkopplad utrustning kan hanteras. På en strategisk nivå erbjuder verktyget Maptionnaire möjligheter att aggregera, analysera, och presentera data från uppkopplad utrustning. För att realisera potentialen hos dessa (och andra) verktyg krävs dock att Södertälje kommun ställer nya krav och utarbetar nya rutiner vid upphandling då kostnaderna för att integrera uppkopplad utrustning annars skulle bli ohållbar. En LCA har genomförts för att utvärdera miljöpåverkan från Internet of Things (IoT) systemet i Södertälje centrum för smart sophämtning ur ett livscykelperspektiv. Med koppling till kommunens klimatstrategi har miljöpåverkan med fokus på klimatpåverkan prioriterats. Den visar att IoT-systemet enbart utgör en liten del av klimatpåverkan (122 kg CO2 eq per år), vilket främst härrör från gateways (50%) och sensorer (27%) och användning av Internet (23%). Sophämtningen bidrar med cirka 12 ton CO2 eq per år, vilket främst bidrog till användningen av fossilbaserade avfallspåsar i plast (96%) och HVO-baserade transporter (4%). Vidare visar LCAn att potential för framtida klimatsmart sophämtningssystemet ligger inom minskad användning av fossila plastpåsar och smart planering av sophämtning för att reducera transporter. Södertälje har redan minskat sin klimatpåverkan från transporter (under 2016) genom byte från diesel till HVO. För ett system med 160 papperskorgar (studiens utgångspunkt) innebar detta 83% minskning, från 2,3 ton till 380 kg. Enbart två ton av denna minskning härrör från fossilfria transporter (resp. 8,75 ton för ett möjligt framtida system med 700 papperskorgar). Dock visar resultaten att ännu mer klimatpåverkan kan minskas genom att inte använda fossila plastpåsar, nästan 12 ton (resp. 50 ton för 700 papperskorgar). Detta motsvara fem resor till Thailand (2,5 ton per resa) eller utsläpp för fyra invånare (2,8 ton per invånare) för året 2030. För ett system med 700 papperskorgar betyder det minst 20 resor till Thailand eller utsläpp för upp till 20 invånare. Vidare har projektet ett fokus på inkludering av medborgare i frågor kring hållbarhet, med syftet att informera, engagera och inkludera medborgare i målet med att uppnå hållbar resurshantering. Medborgardialog kan ske på många olika vis och innebära olika saker. Nulägesanalysen visar att flera olika aktiviteter genomförts på området, och att dessa framförallt kan kopplas till kategorierna ”information” och ”konsultation”, men där också det finns kommande inslag av ”dialog” med till exempel det hackathon som planeras. Från nulägesanalysen noterades dock en möjlighet till utökat fokus på medborgardialog i Södertälje, samt att det finns en medvetenhet om behovet av att inkludera många olika grupper i denna dialog, men det noterades även en utmaning vad gäller inkludering och olika språk. Denna rapport har fokus på nulägesanalys. I och med denna analys går projektet sedan in i en ny fas, med fokus på test och utvärdering av koncept, med ett fortsatt fokus på digitalisering, miljöbedömning och medborgardialog. Ett hackathon, Hack for Södertälje, planeras också på projektets tema: Det inkluderande, hållbara och uppkopplade samhället.

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  • 23.
    Brunklaus, Birgit
    et al.
    RISE Research Institutes of Sweden, Samhällsbyggnad, Systemomställning och tjänsteinnovation.
    Chiew, Yoon Lin
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Lundström, Anders
    Umeå University, Sweden.
    Nilsson-Lindén, Hanna
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Saarikko, Ted
    Umeå University, Sweden.
    The inclusive, sustainable and connected society : IoT implementation in a Swedish municipality2021Konferensbidrag (Övrigt vetenskapligt)
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  • 24.
    Brunklaus, Birgit
    et al.
    RISE Research Institutes of Sweden, Samhällsbyggnad, Systemomställning och tjänsteinnovation.
    Diener, Derek
    RISE Research Institutes of Sweden, Samhällsbyggnad, Systemomställning och tjänsteinnovation.
    Enebog, Emma
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Hautajärvi Stenmark, Heidi
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Lundahl, Jenny
    RISE Research Institutes of Sweden, Digitala system, Mobilitet och system.
    Matteoni, Marina
    RISE Research Institutes of Sweden, Samhällsbyggnad, Systemomställning och tjänsteinnovation.
    Nyström, Thomas
    RISE Research Institutes of Sweden, Samhällsbyggnad, Systemomställning och tjänsteinnovation.
    Nilsson-Lindén, Hanna
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Renström, Sara
    RISE Research Institutes of Sweden, Digitala system, Datavetenskap.
    Den cirkulära bilen (förstudie)2023Rapport (Övrigt vetenskapligt)
    Abstract [sv]

    Syftet med förstudien Den cirkulära bilen var att börja bygga konkreta visioner som möjliggör att Sverige har en cirkulärt anpassad bilflotta med fossilfria och klimatneutrala transporter år 2045 och att bygga en solid bas för ett steg 2-projekt, som i sin tur kommer att ge stöd och kapacitet för aktörer att accelerera den cirkulära bilvärdekedjan. Projektet har samlat 13 parter från hela värdekedjan och gemensamt lagt grunden till vidare arbete i ett fortsättningsprojekt – en ansökan som genererat intresse från ett stort antal parter både befintliga och nytillkommande. Inom studien har startmöten och workshops genomförts där parter samlats digitalt och frågeställningar sonderats. Intervjuer har genomförts med parter där möjligheter och utmaningar med omställningen diskuterats. Studiebesök har genomförts där kunskapsdelning skett och samverkan möjliggjorts. Fysisk workshop har genomförts med samtliga parter. Här tittade man gemensamt på trender och möjliga framtidsscenarios genom hela systemet. Detta gav en bra grund för det vidare arbetet med steg 2. Förstudien har genererat stort intresse från aktörer i hela värdekedjan, skapat nya kontakter och möjligheter till samverkan och blivit uppstarten på en gemensam kunskapsresa för verklig förändring. Studien har initierat arbete brett i värdekedjan kopplat till gemensamma frågeställningar samt framtidsspaningar, vilket möjliggör gemensamt arbete för bred omställning och tydliggjort behovet av åtgärder som förflyttar hela systemet. Detta ses som en god grund för ett steg 2 projekt med förutsättningar för att förverkliga den cirkulära bilvärdekedjan.

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  • 25.
    Burkhardt, Felix
    et al.
    University of Freiburg, Germany.
    Harlass, Markus
    University of Freiburg, Germany.
    Adolfsson, Erik
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Vach, Kirstin
    University of Freiburg, Germany.
    Spies, Benedikt
    University of Freiburg, Germany.
    Kohal, Ralf-Joachim
    University of Freiburg, Germany.
    A novel zirconia-based composite presents an aging resistant material for narrow-diameter ceramic implants2021Ingår i: Materials, ISSN 1996-1944, E-ISSN 1996-1944, Vol. 14, nr 9, artikel-id 2151Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    A novel ceria-stabilized zirconia-alumina-aluminate composite (Ce-TZP-comp) that is not prone to aging presents a potential alternative to yttrium-stabilized zirconia for ceramic oral implants. The objective of this study was to evaluate the long-term stability of a one-piece narrow-diameter implant made of Ce-TZP-comp. Implant prototypes with a narrow (3.4 mm) and regular (4.0 mm) diameter were embedded according to ISO 14801, and subgroups (n = 8) were subsequently exposed to dynamic loading (107 cycles, 98N) and/or hydrothermal treatment (aging, 85◦C). Loading/aging was only applied as a combined protocol for the 4.0 mm diameter implants. One subgroup of each diameter remained untreated. One sample was cross-sectioned from each subgroup and evaluated with a scanning electron microscope for phase-transformation of the lattice. Finally, the remaining samples were loaded to fracture. A multivariate linear regression model was applied for statistical analyses (significance at p < 0.05). All samples withstood the different loading/aging protocols and no transformation propagation was observed. The narrow diameter implants showed the lowest fracture load after combined loading/aging (628 ± 56 N; p < 0.01), whereas all other subgroups exhibited no significantly reduced fracture resistance (between 762 ± 62 and 806 ± 73 N; p < 0.05). Therefore, fracture load values of Ce-TZP-comp implants suggest a reliable intraoral clinical application in the anterior jaw regions. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.

  • 26.
    Burkhardt, Felix
    et al.
    University of Freiburg, Germany; Lennart Riemer Zahnarztpraxis Franzem, Germany.
    Spies, Benedikt
    University of Freiburg, Germany; Lennart Riemer Zahnarztpraxis Franzem, Germany.
    Riemer, Lennart
    University of Freiburg, Germany; Lennart Riemer Zahnarztpraxis Franzem, Germany.
    Adolfsson, Erik
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Doerken, Sam
    University of Freiburg, Germany.
    Kohal, Ralf J.
    University of Freiburg, Germany; Lennart Riemer Zahnarztpraxis Franzem, Germany.
    Fracture resistance and crystal phase transformation of a one- and a two-piece zirconia implant with and without simultaneous loading and aging—An in vitro study2021Ingår i: Clinical Oral Implants Research, ISSN 0905-7161, E-ISSN 1600-0501, Vol. 32, nr 11, s. 1288-1298Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Objective: To evaluate the influence of artificial aging on the transformation propagation and fracture resistance of zirconia implants. Methods: One-piece (with integrated implant abutment, 1P; regular diameter [4.1mm]; n = 16) and two-piece (with separate implant abutment, 2P; wide diameter [5 mm]; n = 16) zirconia implants were embedded according to ISO 14801. A two-piece titanium–zirconium implant (Ti-Zr; 4.1 mm diameter) served as a control (n = 16). One subgroup (n = 8) of each system was simultaneously dynamically loaded (107 cycles; 98N) and hydrothermally aged (85°C, 58 days), while the other subgroup (n = 8) remained untreated. Finally, specimens were statically loaded to fracture. Potential crystal phase transformation was examined at cross sections using scanning electron microscopy (SEM). A multivariate linear regression model was applied for statistical analyses. Results: The fracture resistance of 1P (1,117 [SD = 38] N; loaded/aged: 1,009 [60] N), 2P (850 [36] N; loaded/aged: 799 [84] N), and Ti-Zr implants (1,338 [205] N; loaded/aged: 1,319 [247] N) was not affected significantly by loading/aging (p =.171). However, when comparing the systems, they revealed significant differences independent of loading/aging (p ≤.001). Regarding the crystal structure, a transformation zone was observed in SEM images of 1P only after aging, while 2P showed a transformation zone even before aging. After hydrothermal treatment, an increase of this monoclinic layer was observed in both systems. Conclusions: The Ti-Zr control implant showed higher fracture resistance compared to both zirconia implants. Loading/aging had no significant impact on the fracture resistance of both zirconia implants. The wide-body 2P zirconia implant was weaker than the regular body 1P implant. © 2021 The Authors. 

  • 27.
    Cahill, Patrick
    et al.
    Cawthron Institute, New Zealand.
    Grant, Thomas
    University of Auckland, New Zealand.
    Rennison, David
    University of Auckland, New Zealand.
    Champeau, Olivier
    Cawthron Institute, New Zealand.
    Boundy, Michael
    Cawthron Institute, New Zealand.
    Passfield, Emillie
    Cawthron Institute, New Zealand.
    Berglin, Mattias
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Brimble, Margaret
    University of Auckland, New Zealand.
    Svenson, Johan
    Cawthron Institute, New Zealand.
    Nature-Inspired Peptide Antifouling Biocide: Coating Compatibility, Field Validation, and Environmental Stability2023Ingår i: ACS Applied Bio Materials, E-ISSN 2576-6422, Vol. 6, nr 6, s. 2415-2425Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    This study reports the development of a class of eco-friendly antifouling biocides based on a cyclic dipeptide scaffold, 2,5-diketopiperazine (2,5-DKP). The lead compound cyclo(N-Bip-l-Arg-N-Bip-l-Arg) (1) was synthesized in gram amounts and used to assess the compatibility with an ablation/hydration coating, efficacy against biofouling, and biodegradation. Leaching of 1 from the coating into seawater was assessed via a rotating drum method, revealing relatively stable and predictable leaching rates under dynamic shear stress conditions (36.1 ± 19.7 to 25.2 ± 9.1 ng-1 cm-2 day-1) but low or no leaching under static conditions. The coatings were further analyzed using time-of-flight secondary ion mass spectrometry (ToF-SIMS), with 1 seen to localize at the surface of the coating in a surfactant-like fashion. When coatings were deployed in the ocean, detectable reductions in biofouling development were measured for up to 11 weeks. After this time, biofouling overwhelmed the performance of the coating, consistent with leaching kinetics. Biodegradation of 1 in seawater was assessed using theoretical oxygen demand and analytical quantification. Masking effects were observed at higher concentrations of 1 due to antimicrobial properties, but half-lives were calculated ranging from 13.4 to 16.2 days. The results can rationally inform future development toward commercial antifouling products. 

  • 28.
    Cano, María Emilia
    et al.
    Université de Picardie Jules Verne, France; Universidad de Buenos Aires, Argentina.
    Lindgren, Åsa
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Rosendahl, Jennifer
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Johansson, Jenny
    RISE Research Institutes of Sweden, Samhällsbyggnad, Certifiering.
    Garcia-Martin, Alberto
    Universidad Complutense de Madrid, Spain.
    Galan, Miguel Ladero
    Universidad Complutense de Madrid, Spain.
    Kovensky, José
    Université de Picardie Jules Verne, France.
    Chinga Carrasco, Gary
    RISE Research Institutes of Sweden, Bioekonomi och hälsa, Material- och ytdesign.
    Characterization of carboxylated cellulose nanofibrils and oligosaccharides from Kraft pulp fibers and their potential elicitor effect on the gene expression of Capsicum annuum2024Ingår i: International Journal of Biological Macromolecules, ISSN 0141-8130, E-ISSN 1879-0003, Vol. 267, artikel-id 131229Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Biomass-derived oligo- and polysaccharides may act as elicitors, i.e., bioactive molecules that trigger plant immune responses. This is particularly important to increase the resistance of plants to abiotic and biotic stresses. In this study, cellulose nanofibrils (CNF) gels were obtained by TEMPO-mediated oxidation of unbleached and bleached kraft pulps. The molecular structures were characterized with ESI and MALDI MS. Analysis of the fine sequences was achieved by MS and MS/MS of the water-soluble oligosaccharides obtained by acid hydrolysis of the CNF gels. The analysis revealed the presence of two families: one corresponding to homoglucuronic acid sequences and the other composed by alternating glucose and glucuronic acid units. The CNF gels, alone or with the addition of the water-soluble oligosaccharides, were tested on Chili pepper (Capsicum annuum). Based on the characterization of the gene expression with Next Generation Sequencing (NGS) of the C. annuum’s total messenger RNA, the differences in growth of the C. annuum seeds correlated well with the downregulation of the pathways regulating photosynthesis. A downregulation of the response to abiotic factors was detected, suggesting that these gels would improve the resistance of the C. annuum plants to abiotic stress due to, e.g., water deprivation and cold temperatures. 

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  • 29.
    Centerholt, Victor
    et al.
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Kjiddero, Frida
    AKOA, Sweden.
    Saarikko, Ted
    Umeå University, Sweden.
    Grahn, Sten
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning. Mälardalen University, Sweden.
    Value Chains vs. Ecosystems: Current Perspectives among Swedish SMEs Entering the Interconnected World of IoT2020Ingår i: Advances in Transdisciplinary Engineering at SPS2020, IOS Press BV , 2020, s. 489-500Konferensbidrag (Refereegranskat)
    Abstract [en]

    Smart connected industrial products and the Internet of Things (IoT) are transforming the industrial business landscape in a radical way. To reach the full potential of IoT-Technologies manufacturing firms are forced to rethink almost every aspect of their value creation process. To utilize this promising digital technology and to cope with the new market conditions of IoT environments, research shows that industrial firms have to make a fundamental shift in value creation logic and break free from the value chain perspective of business. Instead they have to embrace a view where value is co-created within ecosystems in both a vertical and a horizontal manner. By exploring the value creation logic of small and medium sized (SME) Swedish industrial machinery manufacturers, this study contributes to a deeper understanding of how manufacturing firms view their value creation processes and how aligned this logic is to the latest research in IoT. The study found that Swedish industrial machine manufacturers do understand the transformative force of IoT-Technologies and see great business opportunities to utilize IoT in their business. The study, however, identified a lack of co-creation and difficulties in embracing an ecosystem perspective. While quick to embrace change on a technical level, respondents still adhere to a firm-centric and linear perspective of value creation, with a strong attachment to the value chain concept. The study suggests that it is not a lack of technical proficiency or engineering know-how, but rather an adherence to goods-dominant logic and attachment to the value chain concept that prevent Swedish SME manufacturers from fully embracing the growing market of industrial IoT. Hence, we see an urgent need for both practitioners and academia to shift their attention from the dazzling potential of cutting-edge technologies to the nitty-gritty business of incorporating co-creation and ecosystem-Thinking into current business practices. © 2020 The authors.

  • 30.
    Chavez, Zuhara
    et al.
    KTH Royal Institute of Technology, Sweden.
    Baalsrud Hauge, Jannicke
    KTH Royal Institute of Technology, Sweden.
    Bellgran, Monica
    KTH Royal Institute of Technology, Sweden.
    Gullander, Per
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Johansson, Mats
    Chalmers University of Technology, Sweden.
    Medbo, Lars
    Chalmers University of Technology, Sweden.
    Medbo, Per
    Chalmers University of Technology, Sweden.
    Ström, Mikael
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Digital Tools and Information Needs Assessment for Efficient Deviation Handling in SMEs2020Ingår i: Advances in Transdisciplinary Engineering at SPS2020, IOS Press BV , 2020, s. 24-35Konferensbidrag (Refereegranskat)
    Abstract [en]

    In a time of change focusing on the application of technology, there is a high risk of underestimating the compliance of internal needs and adaption to context. The research study employs a qualitative approach using the case study methodology. The source of data comes from five different manufacturing companies categorized as Small to Medium Size Enterprises (SMEs). A multidisciplinary team performed semi-structured interviews and fieldwork at each site, along with regular online meetings with the partners. The study employs five dimensions of the information quality perspective to assess information utilized to support deviation handling and connects the information quality deficiencies to the digital tools' impact. The empirical findings indicate the need for the companies to perform a requirement analysis of information needs before the adoption of digital systems or digital tools, to assess their current state in terms of data and information. The paper discusses the impact digital tools may have on deviation management in SMEs and under which circumstances digital tools could improve deviation management. Lastly, this paper intends to shed light on the utilization of digital technologies for disturbance handling on the production shop floor. © 2020 The authors

  • 31.
    Chen, Xiaoxia
    et al.
    Chalmers University of Technology, Sweden.
    Kurdve, Martin
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning. Chalmers University of Technology, Sweden.
    Johansson, Björn
    Chalmers University of Technology, Sweden.
    Despeisse, Melanie
    Chalmers University of Technology, Sweden.
    Enabling the twin transitions: Digital technologies support environmental sustainability through lean principles2023Ingår i: Sustainable Production and Consumption, ISSN 2352-5509, Vol. 38, s. 13-27Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Manufacturing companies seek innovative approaches to achieve successful Green and Digital transitions, where adopting lean production is one alternative. However, further investigation is required to formulate the strategy with practical inputs and identify what digital technologies could be applied with which lean principles for environmental benefits. Therefore, this study first conducted a case study in three companies to collect practice-based data. A complementary literature review was then carried out, investigating the existing frameworks and complementing practices of digitalized lean implementations and the resulting environmental impact. Consequently, the Internet of Things and related connection-level technologies were identified as the key facilitators in lean implementations, specifically in visualization, communication, and poka-yoke, leading to environmental benefits. Furthermore, a framework of DIgitalization Supports Environmental sustainability through Lean principles (DISEL) was proposed to help manufacturing companies identify the opportunities of digitalizing lean principles for Environmental sustainability, thus enabling the twin transitions and being resilient. © 2023 The Authors

  • 32.
    Chiew, Yoon Lin
    et al.
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Brunklaus, Birgit
    RISE Research Institutes of Sweden, Samhällsbyggnad, Systemomställning och tjänsteinnovation.
    Life cycle assessment of Internet of Things(IoT) solution in Södertälje municipality– A smart waste collection system2021Rapport (Övrigt vetenskapligt)
    Abstract [en]

    Internet of things (IoT) is expected to transform the way we live, work, and learn. Using IoT can be a game-changer for municipalities to move towards sustainability. Within the Vinnova financed project, the municipality wants to explore how IoT can enable route optimization and placement planning for increased operational efficiency. The aim of this study is to enhance the knowledge of the environmental benefits of IoT systems in the waste collection system in the city center of Södertälje. This life cycle assessment, LCA, will support the project by identifying environmental hotspots. The LCA study was performed in Jan-Sep 2021. The functional unit of the study has been set to 1 year of IoT system service for 160 litter bins in city center of Södertälje. The studied system is a cradle-to-grave system, including raw materials, sensors and gateways, use phase, and end of life the sensors and gateways, internet connection, as well as the cloud services. Inventory information have been collected mainly from Södertälje, suppliers, and the service providers. Generic data, such as electricity mix, and transports have been taken from the Ecoinvent database and literature. This study has evaluated the environmental impacts of IoT system in Södertälje for the case of smart waste collection system installed in the city center in a life cycle perspective. The objective of the study has been: 1. To estimate the environmental impact (with focus on climate change impact) of IoT system in Södertälje and find out the hotspots within the system in a life cycle perspective. The climate change impact of the IoT system solution in Södertälje is estimated about 120 kg CO2eq per year, which mainly contributes from the gateways (50%) and sensors (27%) and the use of internet (23%). 2. To estimate the environmental impact (focus on climate change impact) of the waste collection system (without IoT system) and find out the hotspots within the system. The climate change impact of the current waste collection system in the city centre of Södertälje contributes approximately 12t CO2eq per year, which mainly contributed from the use of fossil-based plastic trash bags (96%) and the HVO based transport (4%). 3. To compare the current with the future waste collection system (including IoT system for planning and service). To compare the current with the future waste collection system, we use scenarios (see Figure 20 for results). At the starting point of the study (scenario 1), we present results that are based on assumptions and have the same CO2 emissions for the transport and the trash bags. The results were based on diesel (50%) and recycled plastic trash bags (50%). The recycled plastic is made of 80% recycled LDPE and 20% virgin LDPE (Tingstad, 2021). The next step (scenario 2) of the study, we present results that are based on direct data of the current system. The results were based on HVO and fossil trash bags, which results into 11.5 t CO2 for fossil bags and 380 kg CO2eq per year for transport and 120 kg CO2eq extra for the IoT system. The last step (scenario 3) of the study, we present results that are based on future assumptions. The results were based on using no bags and no CO2 emission from bags, which results into 120 kg CO2eq for the IoT system and 380kg CO2eq for the transport and 0 kg CO2eq for the trash bags. The future waste collection system needs to be better than the current system. That means, the future waste collection system needs to reduce the CO2eq emissions by at least 120 kg CO2eq to break-even the extra IoT system. For the IoT system to have an effect, at least 32% of the transport (km) or the number of trash bags used need to be reduced (50 bins of 160 bins), in order to outweighs the extra CO2eq from the IoT system (Figure 21). - A reduction of trp km or trash bags by 32% reduce CO2eq by 120 kg. (=IoT system). - A reduction of trp km or trash bags by 64% reduce CO2eq by 240 kg. (> IoT system).

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  • 33.
    Chiew, Yoon Lin
    et al.
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Brunklaus, Birgit
    RISE Research Institutes of Sweden, Samhällsbyggnad, Systemomställning och tjänsteinnovation.
    Life cycle assessment of IoT system in Södertälje – The case of textile waste collection and the municipality’s recycling stations2023Rapport (Övrigt vetenskapligt)
    Abstract [en]

    Internet of things (IoT) is expected to transform the way we live, work, and learn. Using IoT can be a game-changer for municipalities to move towards sustainability. Within the Vinnova financed project, The inclusive, sustainable, and connected society, the municipality wants to explore how IoT can enable route optimization and placement planning for increased operational efficiency. The aim of these environmental studies is to enhance the knowledge of the environmental benefits of IoT systems in three parts of the waste collection systems and services provided in the municipality of Södertälje: Waste collection in the city centre (Telge Återvinning), Textile collection (Human Bridge) and Recycling stations (Telge Återvinning). The LCA results for waste collection in the city centre are documented in Chiew & Brunklaus (2021); while the main LCA results and conclusions for textile collection (part 2) and recycling stations (part 3) are summarized in this report. The results for all three types of waste collection system show that the implementation of the IoT system is quite low (<1%). In this study, the climate impacts of both textile waste collection and recycling stations services per year were identified with LCA. By using the actor analysis, we found that in both the textile waste collection and the recycling stations services, the major climate impacts come from citizens, e.g., in the case of the textile waste collection service. The climate impact of transportation of the citizens to the textile station is 36%, followed by the plastic or paper bags from the citizens is 22% of the total impact of the textile waste, while the transportation of citizens to the recycling stations is even higher, such as 70% of the total impact of the recycling station system. The textile collection and recycling stations showed that citizen’s choice has huge impact on the CO2 emission. Re-used and recycled textiles, instead of incinerating can save up to 23-44kg CO2 per kg of new textile produced. The recycling stations collects almost 9kt of waste, which are consumer products (e.g. bicycles, furniture, electronic devices and car decks). Re-used products can save between 100kg CO2 eq per bicycle up to 300kg CO2 eq per electronic devices, such as electric tools or laptop computers, as well as 28kg CO2 eq per car decks. On the other hand, the service provided by Södertälje has a huge influence on the citizens choice. The “rullande återvinning” (rolling service), in which Telge Återvinning arranged trucks to collect bulky waste closer to the citizen can reduce the emission that is caused by the citizen transportation. In addition, the IoT system installed in the recycling station can provide good information to the citizen to avoid congestion time and paying for an empty visit due to long queue in the recycling stations. The service provided by Human Bridge and Telge Återvinning can be improved. However, both have already started to implement green choices. The environmental choices already made by Human Bridge (part 2) include the choice of thinner and recycled plastic bags and the choice of green electricity. The environmental choices already made by Telge Återvinning (part 3) include the choice of transportation (HVO instead of diesel) and the choice of green electricity. The recommendations for the future could include better service for the citizens (rolling service) and setting requirements on the service provider, such as in the textile collection (fossil-free transport).

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  • 34.
    Chinga Carrasco, Gary
    et al.
    RISE Research Institutes of Sweden, Bioekonomi och hälsa, Material- och ytdesign.
    Pasquier, Eva
    RISE Research Institutes of Sweden, Bioekonomi och hälsa, Material- och ytdesign.
    Solberg, Amalie
    RISE Research Institutes of Sweden, Bioekonomi och hälsa, Material- och ytdesign.
    Leirset, Ingebjørg
    RISE Research Institutes of Sweden, Bioekonomi och hälsa, Material- och ytdesign.
    Stevanic Srndovic, Jasna
    RISE Research Institutes of Sweden, Bioekonomi och hälsa, Material- och ytdesign.
    Rosendahl, Jennifer
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Håkansson, Joakim
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning. University of Gothenburg, Sweden.
    Carboxylated nanocellulose for wound healing applications – Increase of washing efficiency after chemical pre-treatment and stability of homogenized gels over 10 months2023Ingår i: Carbohydrate Polymers, ISSN 0144-8617, E-ISSN 1879-1344, Vol. 314, artikel-id 120923Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    To commercialize a biomedical product as a medical device, reproducibility of production and time-stability are important parameters. Studies of reproducibility are lacking in the literature. Additionally, chemical pre-treatments of wood fibres to produce highly fibrillated cellulose nanofibrils (CNF) seem to be demanding in terms of production efficiency, being a bottleneck for industrial upscaling. In this study, we evaluated the effect of pH on the dewatering time and washing steps of 2,2,6,6-Tetramethylpiperidinyloxy (TEMPO)-mediated oxidized wood fibres when applying 3.8 mmol NaClO/g cellulose. The results indicate that the method does not affect the carboxylation of the nanocelluloses, and levels of approximately 1390 μmol/g were obtained with good reproducibility. The washing time of a Low-pH sample was reduced to 1/5 of the time required for washing a Control sample. Additionally, the stability of the CNF samples was assessed over 10 months and changes were quantified, the most pronounced were the increase of potential residual fibre aggregates, reduction of viscosity and increase of carboxylic acid content. The cytotoxicity and skin irritation potential were not affected by the detected differences between the Control and Low-pH samples. Importantly, the antibacterial effect of the carboxylated CNFs against S. aureus and P. aeruginosa was confirmed. © 2023 The Authors

  • 35.
    Chinga-Carrasco, Gary
    et al.
    RISE Research Institutes of Sweden, Bioekonomi och hälsa, Material- och ytdesign.
    Rosendahl, Jennifer
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Catalán, Julia
    Finnish Institute of Occupational Health, Finland; University of Zaragoza, Spain.
    Nanocelluloses – Nanotoxicology, Safety Aspects and 3D Bioprinting2022Ingår i: Advances in Experimental Medicine and Biology, ISSN 0065-2598, E-ISSN 2214-8019, Vol. 1357, s. 155-177Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Nanocelluloses have good rheological properties that facilitate the extrusion of nanocellulose gels in micro-extrusion systems. It is considered a highly relevant characteristic that makes it possible to use nanocellulose as an ink component for 3D bioprinting purposes. The nanocelluloses assessed in this book chapter include wood nanocellulose (WNC), bacterial nanocellulose (BNC), and tunicate nanocellulose (TNC), which are often assumed to be non-toxic. Depending on various chemical and mechanical processes, both cellulose nanofibrils (CNF) and cellulose nanocrystals (CNC) can be obtained from the three mentioned nanocelluloses (WNC, BNC, and TNC). Pre/post-treatment processes (chemical and mechanical) cause modifications regarding surface chemistry and nano-morphology. Hence, it is essential to understand whether physicochemical properties may affect the toxicological profile of nanocelluloses. In this book chapter, we provide an overview of nanotoxicology and safety aspects associated with nanocelluloses. Relevant regulatory requirements are considered. We also discuss hazard assessment strategies based on tiered approaches for safety testing, which can be applied in the early stages of the innovation process. Ensuring the safe development of nanocellulose-based 3D bioprinting products will enable full market use of these sustainable resources throughout their life cycle.

  • 36.
    Dahlbom, Sixten
    et al.
    RISE Research Institutes of Sweden, Säkerhet och transport, Brand och Säkerhet.
    Bjarnemark, Fanny
    RISE Research Institutes of Sweden, Material och produktion, Kemi och Tillämpad mekanik.
    Nguyen, Björn
    RISE Research Institutes of Sweden, Material och produktion, Kemi och Tillämpad mekanik.
    Petronis, Sarunas
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Mallin, Tove
    RISE Research Institutes of Sweden, Säkerhet och transport, Brand och Säkerhet.
    Analysis of per- and polyfluoroalkyl substances (PFAS) extraction from contaminated firefighting materials: Effects of cleaning agent, temperature, and chain-length dependencies2024Ingår i: Emerging Contaminants, ISSN 2405-6650, E-ISSN 2405-6642, Vol. 10, nr 3, s. 100335-100335, artikel-id 100335Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    This investigation delves into the extraction dynamics of 22 per- and polyfluoroalkyl substances from PFAS contaminated firefighting materials. Two distinct test sets were executed: one contrasting a commercial product with water following an elaborate decontamination procedure, and the other assessing seven washing agents on materials from firefighting installations, with one agent examined at 22 °C and 50 °C. A general tendency for improved desorption at the higher temperature was observed. Furthermore, a discernible influence of the cleaning agent's pH on the extraction of specific PFAS species was observed, elucidating the role of chemical environment in the extraction process. PFAS rebound was studied for a period of up to 157 days, this unveiled a gradual escalation in PFAS22 levels, indicative of a protracted desorption mechanism. Intriguingly, PFAS with abbreviated carbon chains (C4–C6) exhibit superior desorption efficiency compared to their elongated congeners, suggesting a chain-length-dependent decontamination potential. A comparative scrutiny between a commercially available cleaning product, featuring multiple washing and flushing steps, and a water-only treatment regimen underscores the potential efficacy of the former. This exhaustive investigation furnishes nuanced insights into PFAS extraction complexities, offering a foundation for informed decontamination strategies

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  • 37.
    Davis, Rohan A.
    et al.
    Griffith University, Australia.
    Cervin, Gunnar
    University of Gothenburg, Sweden.
    Beattie, Karren D.
    Griffith University, Australia.
    Rali, Topul
    University of Papua New Guinea, Papua New Guinea.
    Fauchon, Marilyne
    University of Brest, France.
    Hellio, Claire
    University of Brest, France.
    Bodin Åkerlund, Lovisa
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Pavia, Henrik
    University of Gothenburg, Sweden.
    Svenson, Johan
    Cawthron Institute, New Zealand.
    Evaluation of natural resveratrol multimers as marine antifoulants2023Ingår i: Biofouling (Print), ISSN 0892-7014, E-ISSN 1029-2454, Vol. 39, nr 8, s. 775-784Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    In the current study we investigate the antifouling potential of three polyphenolic resveratrol multimers (–)-hopeaphenol, vaticanol B and vatalbinoside A, isolated from two species of Anisoptera found in the Papua New Guinean rainforest. The compounds were evaluated against the growth and settlement of eight marine microfoulers and against the settlement and metamorphosis of Amphibalanus improvisus barnacle cyprids. The two isomeric compounds (–)-hopeaphenol and vaticanol B displayed a high inhibitory potential against the cyprid larvae metamorphosis at 2.8 and 1.1 μM. (–)-Hopeaphenol was also shown to be a strong inhibitor of both microalgal and bacterial adhesion at submicromolar concentrations with low toxicity. Resveratrol displayed a lower antifouling activity compared to the multimers and had higher off target toxicity against MCR-5 fibroblasts. This study illustrates the potential of natural products as a valuable source for the discovery of novel antifouling leads with low toxicity. 

  • 38.
    De La Garza, R. G.
    et al.
    Lund University, Sweden.
    Madsen, H.
    Mo-clay Museum, Denmark.
    Sjövall, Peter
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Osbӕck, F.
    Fur Museum, Denmark.
    Zheng, W.
    North Carolina State University, USA.
    Jarenmark, M.
    Lund University, Sweden.
    Schweitzer, M. H.
    Lund University, Sweden; North Carolina Museum of Natural Sciences, USA.
    Engdahl, A.
    Lund University, Sweden.
    Uvdal, P.
    Lund University, Sweden.
    Eriksson, M. E.
    Lund University, Sweden.
    Lindgren, J.
    Lund University, Sweden.
    An ancestral hard-shelled sea turtle with a mosaic of soft skin and scutes2022Ingår i: Scientific Reports, E-ISSN 2045-2322, Vol. 12, nr 1, artikel-id 22655Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    The transition from terrestrial to marine environments by secondarily aquatic tetrapods necessitates a suite of adaptive changes associated with life in the sea, e.g., the scaleless skin in adult individuals of the extant leatherback turtle. A partial, yet exceptionally preserved hard-shelled (Pan-Cheloniidae) sea turtle with extensive soft-tissue remains, including epidermal scutes and a virtually complete flipper outline, was recently recovered from the Eocene Fur Formation of Denmark. Examination of the fossilized limb tissue revealed an originally soft, wrinkly skin devoid of scales, together with organic residues that contain remnant eumelanin pigment and inferred epidermal transformation products. Notably, this stem cheloniid—unlike its scaly living descendants—combined scaleless limbs with a bony carapace covered in scutes. Our findings show that the adaptive transition to neritic waters by the ancestral pan-chelonioids was more complex than hitherto appreciated, and included at least one evolutionary lineage with a mosaic of integumental features not seen in any living turtle. © 2022, The Author(s).

  • 39.
    De La Garza, Randolph
    et al.
    Lund University, Sweden.
    Sjövall, Peter
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Hauff, Rolf
    Urweltmuseum Hauff, Germany.
    Lindgren, Johan
    Lund University, Sweden.
    Preservational modes of some ichthyosaur soft tissues (Reptilia, Ichthyopterygia) from the Jurassic Posidonia Shale of Germany2023Ingår i: Palaeontology, ISSN 0031-0239, E-ISSN 1475-4983, Vol. 66, nr 4, artikel-id e12668Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Konservat-Lagerstätten, such as the Toarcian (Early Jurassic) Posidonia Shale of southwestern Germany, are renowned for their spectacular fossils. Ichthyosaur skeletons recovered from this formation are frequently associated with soft tissues; however, the preserved material ranges from three-dimensional, predominantly phosphatized structures to dark films of mainly organic matter. We examined soft-tissue residues obtained from two ichthyosaur specimens using an integrated ultrastructural and geochemical approach. Our analyses revealed that the superficially-looking ‘films’ in fact comprise sections of densely aggregated melanosome (pigment) organelles sandwiched between phosphatized layers containing fibrous microstructures. We interpret this distinct layering as representing condensed and incompletely degraded integument from both sides of the animal. When compared against previously documented ichthyosaur fossils, it becomes readily apparent that a range of preservational modes exists between presumed ‘phosphatic’ and ‘carbonized’ soft-tissue remains. Some specimens show high structural fidelity (e.g. distinct integumentary layering), while others, including the fossils examined in this study, retain few original anatomical details. This diversity of soft-tissue preservational modes among Posidonia Shale ichthyosaurs offers a unique opportunity to examine different biostratinomic, taphonomic and diagenetic variables that potentially could affect the process of fossilization. It is likely that soft-tissue preservation in the Posidonia Shale was regulated by a multitude of factors, including decay efficiency and speed of phosphatic mineral nucleation; these in turn were governed by a seafloor with sustained microbial mat activity fuelled by high organic matter input and seasonally fluctuating oxygen levels. © 2023 The Authors. 

  • 40.
    Dellve, Lotta
    et al.
    University of Gothenburg, Sweden.
    Williamsson, Anna
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning. KTH Royal Institute of Technology, Sweden.
    Development Work in Swedish Eldercare: Resources for Trustworthy, Integrated Managerial Work During the COVID-19 Pandemic2022Ingår i: Frontiers In Public Health, ISSN 2296-2565, Vol. 10, artikel-id 864272Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    The extensive needs for developments of eldercare addressing working conditions, care quality, influence, and safety was highlighted during the pandemic. This mixed-method study contribute with knowledge about capability-strengthening development work and its importance for trustworthy managerial work, before and during the COVID-19 pandemic. Questionnaire data and narratives from first-line managers immediately before (n = 284) and 16 months into the pandemic (n = 189), structured interviews with development leaders (n = 25), and documents were analyzed. The results identify different focuses of development work. Strategic-level development leaders focused the strengthening of old adults' capabilities. While operational-level leaders approached strengthening employees' capability. First-line managers' rating of their trustworthy managerial work decreased during the pandemic and was associated with their workload, development support and capability-strengthening projects focusing employees' resources. The study demonstrates the gap between strategic and the operational levels regarding understanding of capability set and needed resources for strengthening capabilities and trustworthy, integrated managerial work regarding safety, influence, and quality conditions for old adults and employees. Copyright © 2022 Dellve and Williamsson.

  • 41.
    Diener, Derek
    et al.
    RISE Research Institutes of Sweden, Samhällsbyggnad, Systemomställning och tjänsteinnovation.
    Fallahi, Sara
    RISE Research Institutes of Sweden, Digitala system, Prototypande samhälle.
    Ljungstrand, Peter
    RISE Research Institutes of Sweden, Digitala system, Prototypande samhälle.
    Nilsson-Lindén, Hanna
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Stor Swienkels, Niels
    RISE Research Institutes of Sweden, Digitala system, Prototypande samhälle.
    Bekken Björkman, Max
    Chalmers industriteknik, Sweden.
    Kazmierczak, Karolina
    Chalmers industriteknik, Sweden.
    Klint, Maria
    antrop, Sweden.
    Glimskär, Therese
    antrop, Sweden.
    Mair, Amanda
    antrop, Sweden.
    Produktpass som möjliggörare för cirkulära möbelflöden: Slutrapport2024Rapport (Övrigt vetenskapligt)
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  • 42.
    Eng, Mattias P.
    et al.
    RISE Research Institutes of Sweden, Digitala system, Smart hårdvara.
    Lövberg, Andreas
    RISE Research Institutes of Sweden, Digitala system, Smart hårdvara.
    Misiorny, Maciej
    QRTECH AB, Sweden.
    Söderkvist Vermelin, Wilhelm
    RISE Research Institutes of Sweden, Digitala system, Smart hårdvara. RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Brinkfeldt, Klas
    RISE Research Institutes of Sweden, Digitala system, Smart hårdvara.
    Mishra, Madhav
    RISE Research Institutes of Sweden, Digitala system, Smart hårdvara.
    Simple Hybrid Model for Estimating Remaining Useful Life of SiC MOSFETs in Power Cycling Experiments2023Konferensbidrag (Refereegranskat)
    Abstract [en]

    Recording and prediction of the accumulated damage, which will eventually lead to the failure of power electronic modules, is an aspect of high importance for power electronic systems design and, in particular, for development of Prognostic and Health Management (PHM) schemes for in-field applications. To this end, this paper presents a simple and cost-effective prognostic method for predicting the remaining useful life (RUL) of TO-247 packaged silicon carbide (SiC) metal-oxide semiconductor field-effect transistors (MOSFETs) subjected to power cycling experiments. The model assumes that the major failure mode is bond-wire lift-off and uses a damage accumulation scheme based on Paris’ crack law. The only inputs to the model are historical data on the average junction temperature swing and the temperaturecompensated drain-source ON-state resistance at the peak temperature of the current cycle. Using only these two input values, the model is shown to predict RUL with surprising accuracy for the range of constant current loads determining cycling conditions under which the test data series have been acquired. This work is a first step in an ongoing project towards building more elaborate prognostic schemes for RUL-determination of SiC power MOSFETs in actual working conditions, using physics-informed neural networks (PINNs).

  • 43.
    Eng, Mattias P.
    et al.
    RISE Research Institutes of Sweden, Digitala system, Smart hårdvara.
    Mishra, Madhav
    RISE Research Institutes of Sweden, Digitala system, Smart hårdvara.
    Söderkvist Vermelin, Wilhelm
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Andersson, Dag
    RISE Research Institutes of Sweden, Digitala system, Smart hårdvara.
    Brinkfeldt, Klas
    RISE Research Institutes of Sweden, Digitala system, Smart hårdvara.
    A Link between the Lab and the Real World-A Setup for Accelerated Aging of Power Electronics Using Mission Profiles from the Field2024Ingår i: 25th International Conference on Thermal, Mechanical and Multi-Physics Simulation and Experiments in Microelectronics and Microsystems, EuroSimE 2024, Institute of Electrical and Electronics Engineers Inc. , 2024Konferensbidrag (Refereegranskat)
    Abstract [en]

    To generate data used for developing schemes and models for CM, PHM, and for estimating RUL of power electronic devices, accelerated aging experiments in the form of power cycling are often performed. In these experiments, a set current is passed through the power devices and is turned on and off in regular cycles. Due to the mismatch in CTEs of the materials in the devices, the on/off cycles will generate thermally induced stress in the various material interfaces, which is the main cause of failures. Most of the power cycling setups that are currently used can only manage a single set on-state current level and fixed on/off times (which is also the common standard for lifetime testing); a condition that is very far from most real applications. The experimental setup described here is based on a Gamry Reference 3000AEpotentiostat/galvanostat/ZRA working with a Gamry 30k Booster, which can be programmed to generate a variable load current profile and will thus enable the application of more realistic conditions for accelerated aging of power electronic devices in the lab. This will improve prognostics model development and provide excellent use cases for evaluating the capabilities of the prognostics algorithms for generalization to field conditions. The application of variable load profiles from the field, instead of the regular on/off cycles traditionally used, is not compatible with the commonly used method of using the chip itself as a temperature sensor. Instead, we here present a novel method of estimating the junction temperature using a device specific derivation of thermal parameters from the measured cooling block temperature, case temperature, and dissipated power in conjunction with simulations using the PySpice simulation package implemented in Python. The setup coupled with the new junction temperature estimation is an important step in enabling predictive maintenance of power devices that is currently missing from the power electronics community. © 2024 IEEE.

  • 44.
    Eriksson, Andrea
    et al.
    KTH Royal Institute of Technology, Sweden.
    Dellve, Lotta
    University of Gothenburg, Sweden.
    Williamsson, Anna
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Skagert, Katrin
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    How Conditions and Resources Connected to Digital Management Systems and Remote Work Are Associated with Sustainable Work2022Ingår i: International Journal of Environmental Research and Public Health, ISSN 1661-7827, E-ISSN 1660-4601, Vol. 19, nr 23, artikel-id 15731Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    The current state of work–life transformation will see more white-collar work being performed remotely using digital management systems. There is, however, a lack of research on factors and resources contributing to sustainable work when working remotely using digital management systems. The aim of this study was to study the conditions and resources connected to digital management systems and remote work, and their associations with sustainable work, in terms of process quality, trust, and sense of coherence, when working remotely during the COVID-19 pandemic. An analytical cross-sectional study was performed. Questionnaire data from white-collar employees (n = 484) in two private companies were analyzed with regression models, focusing on the importance of the conditions and resources connected to digital management systems and remote work, stratified by working from home or at the office. The results showed digital conditions and resources being associated with indicators of sustainable work. Furthermore, the results showed that social work relations were additional important explanatory factors for sustainable remote work. This study contributes to the development of a new post-pandemic work–life balance by concluding that sustainable remote work needs to be ensured by functional digital management systems and adequate leadership supporting the development of a positive team and learning climate. © 2022 by the authors.

  • 45.
    Fogelberg, Emmie
    et al.
    University of Skövde, Sweden.
    Kolbeinsson, Ari
    University of Skövde, Sweden.
    Kurdve, Martin
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Mattsson, Sandra
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Salunkhe, Omkar
    Chalmers University of Technology, Sweden.
    Thorvald, Peter
    University of Skövde, Sweden.
    Thuresson, Urban
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Current and best practices in information presentation2024Rapport (Övrigt vetenskapligt)
    Abstract [en]

    Digitalization and automation in industry can have both positive and negative effects on social sustainability. On one hand it can be a basis for monotonous, uncreative, and even dangerous workplaces and in some cases might even result in people losing their work. On the other hand, it can be a base for ergonomically sound and inclusive work, engaging everyone in improvements. This project aims for moving the focus on positive effects for social sustainability while still staying cost efficient and effective in economic and ecologic sustainability for digitalization and automation of work instructions and training in manual operations like assembly, machine operation & setup, maintenance, and material handling. The Industry 4.0 paradigm offers radically increased opportunities for doing just that. For example, increased digitization can create efficiency improvements through shorter lead times and reduced disruptions to production. New generations of technology and software as well as information dissemination can be accelerated and the traceability of products and materials in the industrial systems can be greatly increased. Digitization also provides opportunities to increase industrial resilience to challenges coming from elsewhere, such as demographic change and climate threats. Advanced application of digitization is seen by industries and decision-makers as the most important enabler for achieving the strategic sustainability goals and Agenda2030. A crucial factor for competitiveness is the human contribution. Here too, digitalisation is radically changing the conditions. In the last 20 years, work instructions have been transformed from printed text on paper into an increasingly digital representation. As knowledge increases about how work instructions for the manufacturing industry should be designed, they are rarely designed according to user conditions. At best, this results in a missed opportunity for performance improvements and at worst, it could potentially result in quality deficiencies, efficiency deficiencies and a lower degree of inclusion of staff groups. Digitization and automation permeate both society and industry more and more and there are many different technologies on the market. These can contribute to both increased efficiency and flexibility for the industry. However, there are a lot of challenges to both implement, design, and use instructions. Studies conducted in industry 2014–2018 show that operators and assembly workers only use instructions in 20–25% of cases in the operational phase when they are perceived as inefficient (Fast-Berglund & Stahre, 2013; Mattsson et al., 2018). Of course, this also increases the risks of, for example, assembly errors by not using instructions to the extent that they should be used. The corporate culture and standards are also an important part of how instructions are created and used. Depending on the structure and condition of the company and the production unit, for example, an assembly instruction at one company may include information about the product, process, and work environment, while an assembly instruction at another company includes completely different or only parts of this information. Of course, this is a natural consequence of sometimes far-inherited corporate cultures and traditions, but experience has also shown that it is to a very large extent the nature of work that defines the type of support system needed. In line with increased automation and increasing product variation as a result of increased customisation, operators’ tasks will require more creative work than before where the aim is to enable and handle the results of individual workers' creative thoughts about improvements in their own work situation, increasing cognitive load (Taylor et al., 2020). The development of digitalisation has created new opportunities for improved communication among employees in the manufacturing industry (Oesterreich & Teuteberg, 2016). Therefore, this technological development can and should support operators cognitively (Kaasinen et al., 2020; Mattsson et al., 2016). Although many new digital technologies are being developed and are available (Romero et al., 2016), it is still difficult to implement these so that people's cognitive work is supported. This is often due to the fact that the implementation does not take place in a way that people are comfortable with (Parasuraman & Riley, 1997). In many cases, humans are expected to adapt to technology and not the other way around (Thorvald et al., 2021). To implement better support for their operators, companies should focus on identifying the information needs that exist (Haghi et al., 2018) and then visualize it in a way that is useful to operators. The central aim for the project is to demonstrate how knowledge and systematic development of cognitive support and information design can increase quality and flexibility in future production and how this can be considered in the implementation of digital work instructions. In the industrial case studies, current state-of-practice in information presentation will be investigated and analysed together with state-of-the art knowledge and technology to map successful efforts in industry, identify what it is that makes them successful, or how a particularly challenging situation can be further improved through our knowledge of cognitive work in production.

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  • 46.
    Fries, M. D.
    et al.
    NASA Johnson Space Center, USA.
    Siljeström, Sandra
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Aileen Yingst, R.
    Planetary Science Institute, USA.
    The SHERLOC Calibration Target on the Mars 2020 Perseverance Rover: Design, Operations, Outreach, and Future Human Exploration Functions2022Ingår i: Space Science Reviews, ISSN 0038-6308, E-ISSN 1572-9672, Vol. 218, nr 6, artikel-id 46Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    The Scanning Habitable Environments with Raman and Luminescence for Organics and Chemicals (SHERLOC) is a robotic arm-mounted instrument onboard NASA’s Perseverance rover. SHERLOC combines imaging via two cameras with both Raman and fluorescence spectroscopy to investigate geological materials at the rover’s Jezero crater field site. SHERLOC requires in situ calibration to monitor the health and performance of the instrument. These calibration data are critically important to ensure the veracity of data interpretation, especially considering the extreme martian environmental conditions where the instrument operates. The SHERLOC Calibration Target (SCT) is located at the front of the rover and is exposed to the same atmospheric conditions as the instrument. The SCT includes 10 individual targets designed to meet all instrument calibration requirements. An additional calibration target is mounted inside the instrument’s dust cover. The targets include polymers, rock, synthetic material, and optical pattern targets. Their primary function is calibration of parameters within the SHERLOC instrument so that the data can be interpreted correctly. The SCT was also designed to take advantage of opportunities for supplemental science investigations and includes targets intended for public engagement. The exposure of materials to martian atmospheric conditions allows for opportunistic science on extravehicular suit (i.e., “spacesuit”) materials. These samples will be used in an extended study to produce direct measurements of the expected service lifetimes of these materials on the martian surface, thus helping NASA facilitate human exploration of the planet. Other targets include a martian meteorite and the first geocache target to reside on another planet, both of which increase the outreach and potential of the mission to foster interest in, and enthusiasm for, planetary exploration. During the first 200 sols (martian days) of operation on Mars, the SCT has been analyzed three times and has proven to be vital in the calibration of the instrument and in assisting the SHERLOC team with interpretation of in situ data. © 2022, The Author(s).

  • 47.
    Furberg, Anna
    et al.
    Chalmers University of Technology, Sweden.
    Fransson, Kristin
    RISE Research Institutes of Sweden.
    Zackrisson, Mats
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Larsson, Mikael
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Arvidsson, Rickard
    Chalmers University of Technology, Sweden.
    Environmental and resource aspects of substituting cemented carbide with polycrystalline diamond: The case of machining tools2020Ingår i: Journal of Cleaner Production, ISSN 0959-6526, E-ISSN 1879-1786, Vol. 277, artikel-id 123577Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Synthetic diamond competes with the conventional cemented carbide (WC–Co) tool material in some applications due to its extreme hardness. However, so far, these materials have not been compared from a life cycle perspective regarding their environmental and resource impacts. The aims of this study are i) to provide detailed life cycle assessment (LCA) results for industrial polycrystalline diamond (PCD) production from diamond grit produced via high-pressure high-temperature (HPHT) synthesis and ii) to conduct the first comparative LCA of PCD and WC-Co tools for the cases of wood working and titanium alloys machining. The results show that the main hotspot in HPHT synthesis of diamond grit, which is the main precursor to PCD, is the use of WC-Co in the high-pressure apparatus. In PCD tool production, the electricity input and the use of tungsten and molybdenum contribute the most to environmental and resource impacts. The environmental and resource impacts of the PCD tool production can be reduced with 53–83% if solar electricity and full WC-Co recycling is applied. The comparison shows high environmental and resource improvements when substituting WC-Co tools with PCD tools in wood working, but not in titanium alloys machining. © 2020 The Authors

  • 48.
    Garcia Rivera, Francisco
    et al.
    University of Skövde, Sweden.
    Rostami, Asreen
    RISE Research Institutes of Sweden, Digitala system, Prototypande samhälle.
    Mattsson, Sandra
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Söderlund, Henrik
    Chalmers University of Technology, Sweden.
    How Can XR Enhance Collaboration with CAD/CAE Tools in Remote Design Reviews?2024Ingår i: Advances in Transdisciplinary Engineering, ISSN 2352-751X, Vol. 52, s. 383-394Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    This study studies the challenges of effective communication and collaboration in remote design review meetings (DRMs) and explores the potential of Extended Reality (XR) technologies to address these challenges. The research focuses on identifying recurring communication issues and the preferences of companies within the context of remote DRMs. The study involves qualitative content analysis and industry workshops to uncover the current problems with conventional approaches and the aspirations of companies regarding improved collaboration in the DRM process. Drawing upon the insights gathered from both the workshop and design review observations, this paper highlights the features that are critical for collaborative software to handle online design reviews. XR technologies offer immersive and interactive experiences that can transform communication and collaboration in the context of DRMs. By identifying the specific challenges faced in remote DRMs and understanding the desires of companies, this study sets the stage for a more efficient and effective collaborative process. It emphasizes the adaptability of XR technologies to meet industry needs and integrate seamlessly into existing workflows. The study concludes by highlighting the potential for XR technologies to enhance collaboration in DRMs, making them a valuable tool for various industries. 

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  • 49.
    Garre, Elena
    et al.
    University of Gothenburg, Sweden; Sahlgrenska University Hospital, Sweden.
    Gustafsson, Anna
    University of Gothenburg, Sweden.
    Leiva, Maria
    University of Gothenburg, Sweden.
    Håkansson, Joakim
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning. University of Gothenburg, Sweden; .
    Ståhlberg, Anders
    University of Gothenburg, Sweden; Sahlgrenska University Hospital, Sweden.
    Kovács, Aniko
    Sahlgrenska University Hospital, Sweden.
    Landberg, Göran
    University of Gothenburg, Sweden; Sahlgrenska University Hospital, Sweden.
    Breast Cancer Patient-Derived Scaffolds Can Expose Unique Individual Cancer Progressing Properties of the Cancer Microenvironment Associated with Clinical Characteristics2022Ingår i: Cancers, ISSN 2072-6694, Vol. 14, nr 9, artikel-id 2172Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Breast cancer is a heterogeneous disease in terms of cellular and structural composition, and besides acquired aggressive properties in the cancer cell population, the surrounding tumor microenvironment can affect disease progression and clinical behaviours. To specifically decode the clinical relevance of the cancer promoting effects of individual tumor microenvironments, we performed a comprehensive test of 110 breast cancer samples using a recently established in vivo-like 3D cell culture platform based on patient-derived scaffolds (PDSs). Cell-free PDSs were recellularized with three breast cancer cell lines and adaptation to the different patient-based microenvironments was monitored by quantitative PCR. Substantial variability in gene expression between individual PDS cultures from different patients was observed, as well as between different cell lines. Interestingly, specific gene expression changes in the PDS cultures were significantly linked to prognostic features and clinical information from the original cancer. This link was even more pronounced when ERα-status of cell lines and PDSs matched. The results support that PDSs cultures, including a cancer cell line of relevant origin, can monitor the activity of the tumor microenvironment and reveal unique information about the malignancy-inducing properties of the individual cancer niche and serve as a future complementary diagnostic tool for breast cancer. © 2022 by the authors.

  • 50.
    Gilljam, Karin M
    et al.
    Regenics AS, Norway.
    Stenlund, Patrik
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Standoft, Simon
    RISE Research Institutes of Sweden, Material och produktion, Metodik för produktframtagning.
    Andersen, Sisse Bindslev
    Scantox A/S, Denmark.
    Kaaber, Kari
    Scantox A/S, Denmark.
    Lund, Henrik
    Regenics AS, Norway.
    Bryn, Karl R K
    Regenics AS, Norway.
    Alginate and nanocellulose dressings with extract from salmon roe reduce inflammation and accelerate healing of porcine burn wounds.2023Ingår i: Journal of Burn Care & Research, ISSN 1559-047X, E-ISSN 1559-0488, Vol. 44, nr 5, s. 1140-Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Partial thickness thermal burn wounds are characterized by prolonged inflammatory response, oxidative stress, tissue damage, and secondary necrosis. An optimal dressing for burn wounds would reduce inflammation and oxidative stress while providing a moist, absorbent, and protective cover. We have developed an extract from unfertilized salmon roe containing components with potential anti-inflammatory and antioxidative properties, called HTX. HTX has been combined with alginate from brown algae and nanocellulose from tunicates, and 3D printed into a solid hydrogel wound dressing called Collex. Here, Collex was tested on partial thickness burn wounds in Göttingen minipigs compared to Jelonet, and a variant of Collex without HTX. We found that dermal treatment of burn wounds with Collex resulted in accelerated healing at a majority of measured points over 23 days, compared to treatment with Jelonet. In comparison to Collex without HTX, Collex enhanced healing in the first week after trauma where wound progression was pronounced. Notably, Collex reduced the inflammatory response in the early post-injury phase. The anti-inflammatory response of Collex was investigated in more detail on activated M1 macrophages. We found that Collex, as well as HTX alone, significantly reduced secretion of pro-inflammatory interleukin-1β as well as intracellular levels of oxidative stress. The results from this study indicate that Collex is a potent dressing for treatment of burn wounds, with the anti-inflammatory effect of HTX beneficial in the initial phase, and the moist qualities of the hydrogel favorable both in the initial and the proceeding proliferative phase of wound healing.

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