Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Solvent strategies for loading and release in mesoporous silica
RISE, SP – Sveriges Tekniska Forskningsinstitut, SP Kemi Material och Ytor, Life Science.
RISE, SP – Sveriges Tekniska Forskningsinstitut.
Karlstad University, Sweden.
Karlstad University, Sweden.
2015 (English)In: Colloid and Interface Science Communications, ISSN 2215-0382, Vol. 3, p. 5-8Article in journal (Refereed) Published
Abstract [en]

A model molecule, ibuprofen, was loaded in the pores of mesoporous silica by adsorption from nonpolar solvents (liquid carbon dioxide and cyclohexane) and from a polar solvent (methanol). It was sufficient with a very low concentration of ibuprofen in the nonpolar solvents to achieve maximum loading of ibuprofen in the mesoporous particles. When using liquid carbon dioxide, the pores of the mesoporous silica particles were filled completely with ibuprofen at a lower ibuprofen concentration than similar experiments performed with cyclohexane. When methanol was used, the maximum amount of loaded ibuprofen was never achieved. Furthermore, x-ray scattering showed that all ibuprofen loaded into the mesoporous particles were in an amorphous state. Ibuprofen was released from the mesoporous particles to water within a couple of minutes, regardless of solvent used for loading. It was found that the release of ibuprofen from mesoporous silica was much faster than that of crystalline ibuprofen.

Place, publisher, year, edition, pages
2015. Vol. 3, p. 5-8
Keywords [en]
Mesoporous silica, Green solvents, Liquid carbon dioxide, Adsorption isotherm
National Category
Natural Sciences
Identifiers
URN: urn:nbn:se:ri:diva-6843DOI: 10.1016/j.colcom.2015.01.001Local ID: 23743OAI: oai:DiVA.org:ri-6843DiVA, id: diva2:964684
Available from: 2016-09-08 Created: 2016-09-08 Last updated: 2019-07-09Bibliographically approved

Open Access in DiVA

No full text in DiVA

Other links

Publisher's full text
By organisation
Life ScienceSP – Sveriges Tekniska Forskningsinstitut
In the same journal
Colloid and Interface Science Communications
Natural Sciences

Search outside of DiVA

GoogleGoogle Scholar

doi
urn-nbn

Altmetric score

doi
urn-nbn
Total: 22 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
v. 2.35.8