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Can Cobalt(II) and Chromium(III) ions released from joint prostheses influence the friction coefficient?
KTH Royal Institute of Technology, Sweden; Karolinska Institute, Sweden.
Uppsala University, Sweden.
KTH Royal Institute of Technology, Sweden.
KTH Royal Institute of Technology, Sweden.
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2015 (English)In: ACS Biomaterial Science and Engineering, E-ISSN 2373-9878, Vol. 1, no 8, p. 617-620Article in journal, Letter (Refereed) Published
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Abstract [en]

Cobalt chromium molybdenum alloys (CoCrMo) are commonly used as articulating components in joint prostheses. In this tribocorrosive environment, wear debris and metal ionic species are released and interact with proteins, possibly resulting in protein aggregation. This study aimed to investigate whether this could have an effect on the friction coefficient in a typical material couple, namely CoCrMo-on-polyethylene. It was confirmed that both Co(II) and Cr(III) ions, and their combination, at concentrations relevant for the metal release situation, resulted in protein aggregation and its concomitant precipitation, which increased the friction coefficient. Future studies should identify the clinical importance of these findings.

Place, publisher, year, edition, pages
American Chemical Society (ACS), 2015. Vol. 1, no 8, p. 617-620
Keywords [en]
alloy tribology, CoCrMo, friction, hip joint, protein-metal binding, replacement
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Other Chemistry Topics Tribology (Interacting Surfaces including Friction, Lubrication and Wear) Physical Chemistry
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URN: urn:nbn:se:ri:diva-129DOI: 10.1021/acsbiomaterials.5b00183Scopus ID: 2-s2.0-84969211105OAI: oai:DiVA.org:ri-129DiVA, id: diva2:932906
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SP Chemistry, Materials and Surfaces Publication nr A3669

Available from: 2016-06-02 Created: 2016-05-31 Last updated: 2019-07-02Bibliographically approved

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Rutland, Mark W.

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Life Science
Other Chemistry TopicsTribology (Interacting Surfaces including Friction, Lubrication and Wear)Physical Chemistry

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CiteExportLink to record
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  • apa
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