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Ability of monocyte-derived dendritic cells to secrete oxygen radicals in response to formyl peptide receptor family agonists compared to that of myeloid and plasmacytoid dendritic cells
University of Gothenburg, Sweden.ORCID iD: 0000-0001-6783-4622
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2007 (English)In: Clinical and Vaccine Immunology, ISSN 1556-6811, E-ISSN 1556-679X, Vol. 14, no 3, p. 328-330Article in journal (Refereed) Published
Abstract [en]

We show that human monocyte-derived dendritic cells (DC) differ considerably from freshly isolated blood-derived myeloid and plasmacytoid DC in their abilities to produce reactive oxygen species in response to different agonists to the formyl peptide receptor family and are thus poor representatives of blood DC in this field of research. 

Place, publisher, year, edition, pages
2007. Vol. 14, no 3, p. 328-330
Keywords [en]
agents interacting with transmitter, hormone or drug receptors, chemoattractant, formylmethionylleucylphenylalanine, formylpeptide receptor, formylpeptide receptor like 1, formylpeptide receptor like 2, formylpeptide receptor stimulating agent, oxygen radical, reactive oxygen metabolite, reduced nicotinamide adenine dinucleotide phosphate oxidase, tryptophyllysyltyrosylmethionylvalylaspartylmethionineamide, tryptophyllysyltyrosylmethionylvalylleucylmethionineamide, unclassified drug, antigen presentation, article, bone marrow cell, cell activity, cell type, controlled study, cytokine production, dendritic cell, human, human cell, in vitro study, monocyte, peripheral blood mononuclear cell, plasma cell, priority journal, protein analysis, protein expression, Dendritic Cells, Free Radicals, Humans, Monocytes, Myeloid Cells, Oligopeptides, Reactive Oxygen Species, Receptors, Formyl Peptide
National Category
Natural Sciences
Identifiers
URN: urn:nbn:se:ri:diva-56883DOI: 10.1128/CVI.00349-06Scopus ID: 2-s2.0-34147168125OAI: oai:DiVA.org:ri-56883DiVA, id: diva2:1612577
Available from: 2021-11-18 Created: 2021-11-18 Last updated: 2021-11-18Bibliographically approved

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Nygren, Erik

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