Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Continuously operating biosensor and its integration into a hermetically sealed medical implant
IHP Innovations for High Performance Microelectronics, Germany.
IHP Innovations for High Performance Microelectronics, Germany.
IHP Innovations for High Performance Microelectronics, Germany.
IHP Innovations for High Performance Microelectronics, Germany.
Show others and affiliations
2016 (English)In: Micromachines, E-ISSN 2072-666X, Vol. 7, no 10, article id 183Article in journal (Refereed) Published
Abstract [en]

An integration concept for an implantable biosensor for the continuous monitoring of blood sugar levels is presented. The system architecture is based on technical modules used in cardiovascular implants in order to minimize legal certification efforts for its perspective usage in medical applications. The sensor chip operates via the principle of affinity viscometry, which is realized by a fully embedded biomedical microelectromechanical systems (BioMEMS) prepared in 0.25-μm complementary metal-oxide-semiconductor (CMOS)/BiCMOS technology. Communication with a base station is established in the 402-405 MHz band used for medical implant communication services (MICS). The implant shall operate within the interstitial tissue, and the hermetical sealing of the electronic system against interaction with the body fluid is established using titanium housing. Only the sensor chip and the antenna are encapsulated in an epoxy header closely connected to the metallic housing. The study demonstrates that biosensor implants for the sensing of low-molecular-weight metabolites in the interstitial may successfully rely on components already established in cardiovascular implantology.

Place, publisher, year, edition, pages
2016. Vol. 7, no 10, article id 183
Keywords [en]
Affinity assay, BioMEMS, Biosensor, Continuous glucose monitoring, Medical implant, Metallic housing, Sterilization, Titanium, Amorphous films, Biosensors, CMOS integrated circuits, Electromechanical devices, Embedded systems, Housing, Medical applications, MEMS, Metals, MOS devices, Oxide semiconductors, Sterilization (cleaning), Affinity assays, Biomedical microelectromechanical systems, Cardiovascular implants, Complementary metal oxide semiconductors, Implantable biosensors, Medical implant communication services, Medical implants, Bioassay
National Category
Computer and Information Sciences
Identifiers
URN: urn:nbn:se:ri:diva-32567DOI: 10.3390/mi7100183Scopus ID: 2-s2.0-84994893462OAI: oai:DiVA.org:ri-32567DiVA, id: diva2:1155611
Note

Funding details: 16SV3934, BMBF, Bundesministerium für Bildung und Forschung

Available from: 2017-11-08 Created: 2017-11-08 Last updated: 2024-01-17Bibliographically approved

Open Access in DiVA

fulltext(4256 kB)148 downloads
File information
File name FULLTEXT01.pdfFile size 4256 kBChecksum SHA-512
c3d79aa92b22e6f0573c144caf4b6b425258a89ef0109faa88c5a53b2c9b144d2436ee047289eb9a8ef35536ee12e4bd4abf0ed5e6f409d9f792098e26005aab
Type fulltextMimetype application/pdf

Other links

Publisher's full textScopus

Authority records

Theuer, Lorenz

Search in DiVA

By author/editor
Theuer, Lorenz
By organisation
Acreo
In the same journal
Micromachines
Computer and Information Sciences

Search outside of DiVA

GoogleGoogle Scholar
Total: 148 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

doi
urn-nbn

Altmetric score

doi
urn-nbn
Total: 210 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf