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Guided bone regeneration using individualized ceramic sheets
Maxillofacial Unit Halmstad, Region Halland, Halmstad, Sweden.
Maxillofacial Unit Halmstad, Region Halland, Halmstad, Sweden.
Maxillofacial Unit Halmstad, Region Halland, Halmstad, Sweden.
Maxillofacial Unit Halmstad, Region Halland, Halmstad, Sweden.
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2016 (English)In: International Journal of Oral and Maxillofacial Surgery, ISSN 0901-5027, E-ISSN 1399-0020, ISSN 0901-5027, Vol. 45, no 10, 1246-1252 p.Article in journal (Refereed) Published
Abstract [en]

Guided bone regeneration (GBR) describes the use of membranes to regenerate bony defects. A membrane for GBR needs to be biocompatible, cell-occlusive, non-toxic, and mouldable, and possess space-maintaining properties including stability. The purpose of this pilot study was to describe a new method of GBR using individualized ceramic sheets to perfect bone regeneration prior to implant placement; bone regeneration was assessed using traditional histology and three-dimensional (3D) volumetric changes in the bone and soft tissue. Three patients were included. After full-thickness flap reflection, the individualized ceramic sheets were fixed. The sites were left to heal for 7 months. All patients were evaluated preoperatively and at 7 months postoperative using cone beam computed tomography and 3D optical equipment. Samples of the regenerated bone and soft tissue were collected and analyzed. The bone regenerated in the entire interior volume of all sheets. Bone biopsies revealed newly formed trabecular bone with a lamellar structure. Soft tissue biopsies showed connective tissue with no signs of an inflammatory response. This was considered to be newly formed periosteum. Thus ceramic individualized sheets can be used to regenerate large volumes of bone in both vertical and horizontal directions independent of the bone defect and with good biological acceptance of the material. © 2016 International Association of Oral and Maxillofacial Surgeons

Place, publisher, year, edition, pages
2016. Vol. 45, no 10, 1246-1252 p.
Keyword [en]
ceramic, guided bone regeneration, human, membrane, vertical
National Category
Ceramics
Identifiers
URN: urn:nbn:se:ri:diva-29146DOI: 10.1016/j.ijom.2016.06.005ScopusID: 2-s2.0-84977637559OAI: oai:DiVA.org:ri-29146DiVA: diva2:1083678
Available from: 2017-03-22 Created: 2017-03-22 Last updated: 2017-03-23Bibliographically approved

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