Agile approaches have been highly influential to the software engineering practices in many organizations, and are increasingly being applied in larger companies, and for developing systems outside the pure software domain. To understand more about the current state of agile, its applications to safety-critical systems, and the consequences on innovation and large organizations, a seminar was organized in Stockholm in 2014. This paper gives an overview of the topics discussed at that seminar, a summary of the main results and suggestions for future work as input to a research agenda for agile development of safety-critical software.