Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Sustained release of ibuprofen from polyelectrolyte encapsulated mesoporous carriers
YKI – Ytkemiska institutet.
YKI – Ytkemiska institutet.
YKI – Ytkemiska institutet.
2009 (English)In: Journal of Dispersion Science and Technology, ISSN 0193-2691, E-ISSN 1532-2351, Vol. 30, no 6, 892-902 p.Article in journal (Refereed)
Abstract [en]

Polyelectrolyte multilayers are receiving much attention due to their insolubility and due to structural responses induced in them by changes in solution properties such as, for example, temperature, pH or ionic strength. These characteristics make polyelectrolyte multilayers highly interesting in encapsulation technology and controlled delivery applications. However, producing dry, biocompatible formulations for storage of low molecular weight substances poses a challenge. One possibility is to make use of a well-defined mesoporous inorganic carrier material as host for the model substance (in our case ibuprofen). Control over release properties are enabled by polyelectrolyte encapsulation of the inorganic carrier. We built such multilayers through consecutive deposition of PAH and PSS on top of a first layer ofr PEI. These layers were adsorbed either in presence or absent of ibuprofen. The influence of long time storage, 2 years, of the samples was also investigated. The polyelectrolyte multilayer structure was investigated in detail by Dual Polarization Interferometry (DPI), and we use these data to interpret the measured release profiles.

Place, publisher, year, edition, pages
2009. Vol. 30, no 6, 892-902 p.
Keyword [en]
Dual polarization interferometry (DPI), ibuprofen, mesoporous particles, polyelectrolyte encapsulation, release properties
National Category
Natural Sciences
Identifiers
URN: urn:nbn:se:ri:diva-26861DOI: 10.1080/01932690802644095OAI: oai:DiVA.org:ri-26861DiVA: diva2:1053864
Note
A1966Available from: 2016-12-08 Created: 2016-12-08Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full text
By organisation
YKI – Ytkemiska institutet
In the same journal
Journal of Dispersion Science and Technology
Natural Sciences

Search outside of DiVA

GoogleGoogle Scholar

Altmetric score

Total: 6 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
v. 2.27.0