Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Ellipsometry and TIRF studies of adsorption processes in parenteral drug delivery
YKI – Ytkemiska institutet.
1997 (English)In: Interface science, ISSN 0927-7056, E-ISSN 1573-2746, Vol. 5, 159-167 p.Article in journal (Refereed)
Abstract [en]

Ellipsometry and total internal reflection fluorescence spectroscopy (TIRF) were used for investigating adsorption processes of relevance for parenteral administration of colloidal drug carriers. Emphasis is put on discussing the effects of both protein and surface properties on the adsorption of serum proteins at phospholipid and other surfaces. Furthermore, the adsorption from multicomponent protein systems, such as blood, is addressed, and both competitive and associative adsorption phenomena discussed. The correlation between effects of the drug carrier surface properties on the serum protein adsorption and the circulation time and tissue distribution of colloidal drug carriers is also addressed. Finally, the potential of ellipsometry in another adsorption process of major importance for phagocytosis, i.e., the adsorption of colloidal particles to macroscopic or mesoscopic surfaces, is indicated by investigations of the adsorption of oil-in-water emulsion droplets at silica.

Place, publisher, year, edition, pages
1997. Vol. 5, 159-167 p.
Keyword [en]
Adsorption, ellipsometry, opsonins, PEG, phospholipids, polymers, proteins, TIRF
National Category
Natural Sciences
Identifiers
URN: urn:nbn:se:ri:diva-26595OAI: oai:DiVA.org:ri-26595DiVA: diva2:1053598
Note
A1126Available from: 2016-12-08 Created: 2016-12-08Bibliographically approved

Open Access in DiVA

No full text

By organisation
YKI – Ytkemiska institutet
In the same journal
Interface science
Natural Sciences

Search outside of DiVA

GoogleGoogle Scholar

Total: 4 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
v. 2.26.0