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Biomineralized strontium substituted apatite/titanium dioxide coating on titanium surfaces
YKI – Ytkemiska institutet.
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2010 (English)In: Acta Biomaterialia, ISSN 1742-7061, E-ISSN 1878-7568, Vol. 6, no 4, 1591-1600 p.Article in journal (Refereed)
Abstract [en]

Bone mineral is a multi-substituted calcium phosphate. One of these ion substitutions, strontium, has been proven to increase bone strength and decrease bone resorption. Biomimetics is a potential way to prepare surfaces that provide a favorable bone tissue response, thus enhancing the fixation between bone and implants. Here we prepared double-layered strontium-substituted apatite and titanium dioxide coatings on titanium substrates via mimicking bone mineralization. Morphology, crystallinity, surface chemistry and composition of Sr-substituted coatings formed via biomimetic coating deposition on crystalline titanium oxide substrates were studied as functions of soaking temperature and time in phosphate buffer solutions with different Sr ion concentration. The morphology of the biomimetic apatite changed from plate-like for the pure HA to sphere-like for the Sr ion substituted. Surface analysis results showed that 10-33% of Ca ions in the apatite have been substituted by Sr ions, and that the Sr ions were chemically bonded with apatite and successfully incorporated into the structure of apatite.

Place, publisher, year, edition, pages
2010. Vol. 6, no 4, 1591-1600 p.
Keyword [en]
Biomineralization, Coating, Hydroxyapatite, Strontium, Substitution
National Category
Natural Sciences
Identifiers
URN: urn:nbn:se:ri:diva-26232DOI: 10.1016/j.actbio.2009.10.030OAI: oai:DiVA.org:ri-26232DiVA: diva2:1053234
Note
A3159Available from: 2016-12-08 Created: 2016-12-08Bibliographically approved

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