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Nanocellulose from wood as a biomaterial for biomedical applications
RISE, Innventia, PFI – Paper and Fiber Research Institute.ORCID iD: 0000-0002-6183-2017
Cardiff University School of Dentistry, UK; Swansea University, UK.
NTNU Norwegian University of Science and Technology, Norway.
Cardiff University, UK.
Show others and affiliations
2014 (English)Conference paper, Published paper (Refereed)
Abstract [en]

During the last decades major efforts have been made to produce nanocellulose from wood, where the cellulose fibres are disintegrated into individualized nanofibrils with diameters < 20 nm and lengths in the micrometre scale. Production procedures include various pre-treatments, which yield nanocelluloses with varying chemical and structural properties. One important area of research is nanocellulose as a biomaterial with potential applications within the health sector. As an example, the superior mechanical properties, good moisture retention capability and the ability to form elastic macro-porous structures are advantageous properties for utilizing nanocellulose substrates for wound dressings. However, the utilization of nanocellulose as a substrate for wound dressings requires a thorough assessment of the biocompatibility of the material.  In this respect, it has been demonstrated in-vitro that nanocellulose does not exert acute toxic phenomena on fibroblast cells. However, in addition to in-vitro cytotoxicity testing, in-vivo testing of nanocellulose and the ability of nanocellulose to resist bacterial colonization need a closer attention. This presentation will give an overview of the current research on nanocellulose as a biomaterial for wound dressing applications, considering the morphology of nanocellulose structures, mechanical properties, moisture absorption, cytotoxicity tests and nanocellulose-bacteria interactions.

Place, publisher, year, edition, pages
2014.
National Category
Nano Technology Biomaterials Science
Identifiers
URN: urn:nbn:se:ri:diva-9675OAI: oai:DiVA.org:ri-9675DiVA, id: diva2:968428
Conference
Invited talk, ISN2A 2014 – International symposium on Nanoparticles/Nanomaterials and applications, January 20-22, Lisbon, Portugal.
Available from: 2016-09-12 Created: 2016-09-12 Last updated: 2019-07-31Bibliographically approved

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Chinga-Carrasco, GarySyverud, Kristin

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CiteExportLink to record
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