Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Evaluation of natural resveratrol multimers as marine antifoulants
Griffith University, Australia.
University of Gothenburg, Sweden.
Griffith University, Australia.
University of Papua New Guinea, Papua New Guinea.
Show others and affiliations
2023 (English)In: Biofouling (Print), ISSN 0892-7014, E-ISSN 1029-2454Article in journal (Refereed) Epub ahead of print
Abstract [en]

In the current study we investigate the antifouling potential of three polyphenolic resveratrol multimers (–)-hopeaphenol, vaticanol B and vatalbinoside A, isolated from two species of Anisoptera found in the Papua New Guinean rainforest. The compounds were evaluated against the growth and settlement of eight marine microfoulers and against the settlement and metamorphosis of Amphibalanus improvisus barnacle cyprids. The two isomeric compounds (–)-hopeaphenol and vaticanol B displayed a high inhibitory potential against the cyprid larvae metamorphosis at 2.8 and 1.1 μM. (–)-Hopeaphenol was also shown to be a strong inhibitor of both microalgal and bacterial adhesion at submicromolar concentrations with low toxicity. Resveratrol displayed a lower antifouling activity compared to the multimers and had higher off target toxicity against MCR-5 fibroblasts. This study illustrates the potential of natural products as a valuable source for the discovery of novel antifouling leads with low toxicity. 

Place, publisher, year, edition, pages
Taylor and Francis Ltd. , 2023.
National Category
Ecology
Identifiers
URN: urn:nbn:se:ri:diva-67703DOI: 10.1080/08927014.2023.2263374Scopus ID: 2-s2.0-85173849312OAI: oai:DiVA.org:ri-67703DiVA, id: diva2:1810017
Funder
Australian Research Council, LE0668477, LE140100119, LE0237908, and LP120200339
Note

The authors acknowledge the National Health and Medical Research Council (APP1024314 to RAD), the Australian Research Council for support toward nuclear magnetic resonance (NMR) and mass spectrometry (MS) equipment (LE0668477, LE140100119, and LE0237908), and a linkage research grant (LP120200339 to RAD). HP and GC were supported by the Centre for Marine Chemical Ecology (http://www.cemace.science.gu.se) at the University of Gothenburg.

Available from: 2023-11-06 Created: 2023-11-06 Last updated: 2023-12-22Bibliographically approved

Open Access in DiVA

No full text in DiVA

Other links

Publisher's full textScopus

Authority records

Bodin Åkerlund, Lovisa

Search in DiVA

By author/editor
Bodin Åkerlund, Lovisa
By organisation
Product Realisation Methodology
In the same journal
Biofouling (Print)
Ecology

Search outside of DiVA

GoogleGoogle Scholar

doi
urn-nbn

Altmetric score

doi
urn-nbn
Total: 7 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf