High-frequency shock-type vibrations (HFVs) from, e.g., impact wrenches with a frequency content mainly above 1250 Hz have long been suspected to cause a significant number of vibration injuries, HAVS. These vibrations are unregulated in the current standard for risk estimation, ISO 5349-1; thereby, the risk of injury is suspected to be underestimated. The objective of this study was to investigate the effects on finger tissue subjected to HFVs similar to those from impact wrenches by using a 2D finite element model of a fingertip. The model was validated through experiments. Using the input acceleration from the experiments, the model predicted high pressure variation and particular negative pressures at levels close to 0.1 MPa (1 Bar) or more, which are levels where cavitation in liquid can occur, with a detrimental effect on biological systems.