Endre søk
RefereraExporteraLink to record
Permanent link

Direct link
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annet format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annet språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Monitoring DNA Hybridization with Organic Electrochemical Transistors Functionalized with Polydopamine
Università di Modena e Reggio Emilia, Italy.
Università di Modena e Reggio Emilia, Italy.
RISE Research Institutes of Sweden, Digitala system, Smart hårdvara.ORCID-id: 0000-0001-6889-0351
Max Planck Institute, Germany.
Vise andre og tillknytning
2022 (engelsk)Inngår i: Macromolecular materials and engineering, ISSN 1438-7492, E-ISSN 1439-2054, Vol. 307, nr 5, artikkel-id 2100880Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

Organic electrochemical transistors (OECTs) are finding widespread application in biosensing, thanks to their high sensitivity, broad dynamic range, and low limit of detection. An OECT biosensor requires the immobilization of a biorecognition probe on the gate, or else on the channel, through several, often lengthy, chemical steps. In this work, a fast and straightforward way to functionalize the carbon gate of a fully screen-printed OECT by means of a polydopamine (PDA) film is presented. By chemical immobilization of an amine-terminated single-stranded oligonucleotide, containing the HSP70 promoter CCAAT sequence, on the PDA film, the detection of the complementary DNA strand is demonstrated. Furthermore, the specificity of the developed genosensor is assessed by comparing its response to the fully complementary strand with the one to partially complementary and noncomplementary oligonucleotides. The developed sensor shows a theoretical limit of detection (LOD) of 100 × 10−15 m and a dynamic range over four orders of magnitude. © 2022 The Authors.

sted, utgiver, år, opplag, sider
John Wiley and Sons Inc , 2022. Vol. 307, nr 5, artikkel-id 2100880
Emneord [en]
genosensors, OECTs, organic electronics, polydopamine, Chemical detection, Transistors, Biosensing, DNA hybridization, Dynamic range limits, Functionalized, High sensitivity, Lower limits of detections, Organic electrochemical transistors, Oligonucleotides
HSV kategori
Identifikatorer
URN: urn:nbn:se:ri:diva-58782DOI: 10.1002/mame.202100880Scopus ID: 2-s2.0-85124608615OAI: oai:DiVA.org:ri-58782DiVA, id: diva2:1642212
Merknad

Funding details: Stiftelsen för Strategisk Forskning, SSF, RIT15‐0119; Funding details: Fondazione Umberto Veronesi; Funding details: Associazione Italiana per la Ricerca sul Cancro, AIRC, 21323; Funding details: Horizon 2020, 813863; Funding text 1: This work was funded by the EuroNanoMed III project “AMI”. M.S. was supported by Fondazione Umberto Veronesi. The authors would like to thank Ms. Marie Nillson and Ms. Kathrin Hübscher for the screen‐printing of the OECTs. V.B. was supported by the Swedish Foundation for Strategic Research (Smart Intra‐body network; grant RIT15‐0119). This project received funding from the European Union's Horizon 2020 research and innovation program under the Marie Sklodowska‐Curie grant agreement no. 813863. The laboratory of C.I. was supported by AIRC IG 2018 – ID. 21323 project.

Tilgjengelig fra: 2022-03-04 Laget: 2022-03-04 Sist oppdatert: 2024-01-17bibliografisk kontrollert

Open Access i DiVA

Fulltekst mangler i DiVA

Andre lenker

Forlagets fulltekstScopus

Person

Beni, Valerio

Søk i DiVA

Av forfatter/redaktør
Beni, Valerio
Av organisasjonen
I samme tidsskrift
Macromolecular materials and engineering

Søk utenfor DiVA

GoogleGoogle Scholar

doi
urn-nbn

Altmetric

doi
urn-nbn
Totalt: 5 treff
RefereraExporteraLink to record
Permanent link

Direct link
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annet format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annet språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
v. 2.43.0