Sustainable OrganoCatalyzed Enantioselective Catalytic Michael Additions in Betaine derived Deep Eutectic SolventsVisa övriga samt affilieringar
2023 (Engelska)Ingår i: SynOpen, ISSN 2509-9396, Vol. 7, nr 3, s. 374-Artikel i tidskrift (Refereegranskat) Published
Abstract [en]
The catalyst cinchonidine-squaramide was immobilized within three different deep eutectic solvents (DES): (Betaine: D-Sorbitol: Water), (Betaine: D-Xylitol: Water) and (Betaine: D-Mannitol: Water) and evaluated in a well-known asymmetric Michael addition. These reactions provided excellent yields (up to 99%) and enantioselectivities (up to 98%) using only 1 mol% of catalyst. It was also possible to achieve 9 cycles in reactions with DES (Betaine: D-Sorbitol: Water), proving the high recyclability of this system. In the reactions realized with only 0.5 mol% of catalyst, it was possible to achieve 5 cycles and the products were obtained with high yields (up to 95%) and excellent enantioselectivities (up to 94%), using DES (Betaine: D-Sorbitol: Water)..
Ort, förlag, år, upplaga, sidor
Georg Thieme Verlag , 2023. Vol. 7, nr 3, s. 374-
Nyckelord [en]
Betaine, Cinchonidine-squaramide, Deep Eutectic Solvent (DES), Immobilization, Organocatalysis
Nationell ämneskategori
Organisk kemi
Identifikatorer
URN: urn:nbn:se:ri:diva-65705DOI: 10.1055/a-2117-9971Scopus ID: 2-s2.0-85165607183OAI: oai:DiVA.org:ri-65705DiVA, id: diva2:1786550
Anmärkning
This work received financial support from the Fundação para a Ciência e Tecnologia (FCT Portugal) through the project UIDB/50006/2020 | UIDP/50006/2020.
2023-08-092023-08-092024-06-07Bibliografiskt granskad