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Can Cobalt(II) and Chromium(III) ions released from joint prostheses influence the friction coefficient?
KTH Royal Institute of Technology, Sweden; Karolinska Institute, Sweden.
Uppsala University, Sweden.
KTH Royal Institute of Technology, Sweden.
KTH Royal Institute of Technology, Sweden.
Vise andre og tillknytning
2015 (engelsk)Inngår i: ACS Biomaterial Science and Engineering, E-ISSN 2373-9878, Vol. 1, nr 8, s. 617-620Artikkel i tidsskrift, Letter (Fagfellevurdert) Published
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Text
Abstract [en]

Cobalt chromium molybdenum alloys (CoCrMo) are commonly used as articulating components in joint prostheses. In this tribocorrosive environment, wear debris and metal ionic species are released and interact with proteins, possibly resulting in protein aggregation. This study aimed to investigate whether this could have an effect on the friction coefficient in a typical material couple, namely CoCrMo-on-polyethylene. It was confirmed that both Co(II) and Cr(III) ions, and their combination, at concentrations relevant for the metal release situation, resulted in protein aggregation and its concomitant precipitation, which increased the friction coefficient. Future studies should identify the clinical importance of these findings.

sted, utgiver, år, opplag, sider
American Chemical Society (ACS), 2015. Vol. 1, nr 8, s. 617-620
Emneord [en]
alloy tribology, CoCrMo, friction, hip joint, protein-metal binding, replacement
HSV kategori
Identifikatorer
URN: urn:nbn:se:ri:diva-129DOI: 10.1021/acsbiomaterials.5b00183Scopus ID: 2-s2.0-84969211105OAI: oai:DiVA.org:ri-129DiVA, id: diva2:932906
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SP Chemistry, Materials and Surfaces Publication nr A3669

Tilgjengelig fra: 2016-06-02 Laget: 2016-05-31 Sist oppdatert: 2023-05-25bibliografisk kontrollert

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Rutland, Mark W.

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