Endre søk
RefereraExporteraLink to record
Permanent link

Direct link
Referera
Referensformat
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annet format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annet språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Stability puzzles in phage lambda
RISE., Swedish ICT, SICS.
2002 (engelsk)Inngår i: Physical Review E. Statistical, Nonlinear, and Soft Matter Physics: Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics, ISSN 1063-651X, E-ISSN 1095-3787, Physical Review E, Vol. 65Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

In the absence of RecA-mediated cleavage of the repressor, the [lambda] prophage is exceptionally stable. We develop a stochastic model that predicts the stability of such epigenetic states from affinities of the molecular components. We find that the stability, in particular, depends on the maximum possible cI protein production, and on the number of cro proteins per transcribed mRNA. We apply the model to the behavior of recently published mutants of OR and find, in particular, that a mutant that overexpress cro behaves in a different way than what was predicted, thus suggesting that the current view of the OR switch is incomplete. The approach described here should be generally applicable to the stability of expressed states.

sted, utgiver, år, opplag, sider
2002, 2. Vol. 65
HSV kategori
Identifikatorer
URN: urn:nbn:se:ri:diva-22479DOI: 10.1103/PhysRevE.65.051914OAI: oai:DiVA.org:ri-22479DiVA, id: diva2:1042044
Tilgjengelig fra: 2016-10-31 Laget: 2016-10-31 Sist oppdatert: 2018-01-14bibliografisk kontrollert

Open Access i DiVA

Fulltekst mangler i DiVA

Andre lenker

Forlagets fullteksthttp
Av organisasjonen
I samme tidsskrift
Physical Review E. Statistical, Nonlinear, and Soft Matter Physics: Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics

Søk utenfor DiVA

GoogleGoogle Scholar

doi
urn-nbn

Altmetric

doi
urn-nbn
Totalt: 20 treff
RefereraExporteraLink to record
Permanent link

Direct link
Referera
Referensformat
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annet format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annet språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
v. 2.35.7